Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Blood test detects early signs of Alzheimer’s in middle age

A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age.

14 Jul 2025

Chlamydia pneumoniae and SARS-CoV-2 infections may play a role in Alzheimer's pathogenesis

A recent review by researchers at Philadelphia College of Osteopathic Medicine (PCOM) shows Chlamydia pneumoniae (Cpn) and SARS-CoV-2 infections may play a role in the pathogenesis of Alzheimer's disease.

13 Jul 2025

Brain protein associated with aging not linked to youth contact sports

In recent years, some scientists and advocates have warned that playing contact sports like football and hockey may increase the risk of brain diseases like Alzheimer's disease or chronic traumatic encephalopathy (CTE) due to a buildup of a specific protein in the brain.

11 Jul 2025

Explainable AI helps decode the substrate specificity of γ-secretase enzyme

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research.

11 Jul 2025

Biological age of the brain emerges as a powerful predictor of longevity

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

10 Jul 2025

Experimental treatment reverses paralysis in child with rare mitochondrial disease

The value of a recent biochemical discovery can be seen in the case of an 8-year-old boy. In August 2023 he was able to play typical sports, but by November he needed a wheelchair because of a rare disease that caused worsening paralysis.

9 Jul 2025

Mapping vulnerability or resilience in Alzheimer's through imaging and genetics

It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau - a protein known to misbehave - plays an important role in the disease.

9 Jul 2025

Researchers develop blood test panel for early Alzheimer’s detection

Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, are developing a panel of biomarkers for the early detection of Alzheimer's disease and for distinguishing it from other types of dementia using blood tests.

9 Jul 2025

Mindfulness meditation boosts attention across all age groups

A new study from the USC Leonard Davis School of Gerontology reveals that just 30 days of guided mindfulness meditation can significantly enhance key aspects of attentional control - especially how quickly and accurately people direct their focus - regardless of age.

9 Jul 2025

Unlocking the brain’s language to fight Alzheimer’s

June is Alzheimer's and Brain Awareness Month. With an estimated 55 million people living with Alzheimer's Disease and other forms of dementia worldwide, advancing understanding of these complex diseases is critical to finding new treatments, and potentially, cures.

7 Jul 2025

UCLA Health researchers discover four pathways leading to Alzheimer’s disease

UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.

7 Jul 2025

First large-scale stem cell bank created to investigate Alzheimer’s genetic risk factors

Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10 percent of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong influence on whether or not a person develops AD during their lifetime.

4 Jul 2025

Alzheimer’s protein found to drive lung cancer spread to the brain

Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain – a discovery that offers hope that existing Alzheimer's drugs could be repurposed in preventing cancer's spread.

3 Jul 2025

New AI tool helps clinicians identify brain activity patterns linked to nine types of dementia

Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan - a transformative advance in early, accurate diagnosis.

3 Jul 2025

TET2 mutations in blood stem cells linked to lower Alzheimer's risk

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease.

2 Jul 2025

New brain scan tool predicts aging speed and dementia risk

Any high school reunion is a sharp reminder that some people age more gracefully than others. Some enter their older years still physically spry and mentally sharp. Others start feeling frail or forgetful much earlier in life than expected.

1 Jul 2025

Study uncovers how inflammation in brain blood vessels exacerbates damage in vascular dementia

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.

1 Jul 2025

Glycogen metabolism in neurons emerges as key to fighting Alzheimer's

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

1 Jul 2025

Brain stimulation restores synaptic plasticity in Alzheimer’s mouse model

Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are points of communication between neural cells that are malleable to change based on our experiences.

30 Jun 2025

Shingles and RSV vaccines with AS01 adjuvant reduce dementia risk

Researchers found that older adults who received AS01-adjuvanted shingles or RSV vaccines had a significantly lower risk of developing dementia within 18 months compared to flu vaccine recipients. The protective effect is likely linked to the AS01 adjuvant itself, highlighting new avenues for dementia prevention.

30 Jun 2025