Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Late-life mood disorders may signal neurodegenerative diseases

Depression and bipolar disorder of late onset may represent more than just mental health conditions. Growing evidence suggests these late-life mood disorders (LLMDs) could be not merely risk factors, but rather early warning signs of neurodegenerative diseases like dementia, even when they appear years before memory loss or other cognitive symptoms become apparent.

9 Jun 2025

Blood test shows high accuracy in detecting Alzheimer's disease

Alzheimer's disease, marked by memory loss, trouble concentrating and thinking, and changes in personality and behavior, devastates patients, their families and loved ones.

6 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Alzheimer's gene therapy could help protect the brain from damage and preserve cognitive function

Researchers at University of California San Diego School of Medicine have developed a gene therapy for Alzheimer's disease that could help protect the brain from damage and preserve cognitive function.

5 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Pitt researchers challenge a decades-old assumption about brain plasticity

A new study from Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites - not a shared site - to achieve different types of plasticity.

3 Jun 2025

MIND diet linked to lower risk of dementia across diverse populations

As the U.S. population ages and dementia cases rise, many people are asking whether it is possible to prevent this devastating disease.

3 Jun 2025

Older adults accurately gauge their financial skills until dementia sets in

Older adults are quite aware of their financial abilities – and these abilities actually improve with age – that is, until dementia sets in, according to new research from Binghamton University, State University of New York.

2 Jun 2025

Molecular stress makes old neurons vulnerable to neurodegenerative diseases

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) continues to rise. But the molecular mechanisms behind the deterioration of brain cells have remained elusive.

2 Jun 2025

New discovery reveals immune molecule’s role in Alzheimer’s disease

A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases.

2 Jun 2025

Epileptic seizures more common in frontotemporal dementia patients than previously known

According to a recent study, in patients with frontotemporal dementia (FTD), epileptic seizures are significantly more common than previously known.

2 Jun 2025

New wearable device monitors brain waste clearance during sleep

A new device that monitors the waste-removal system of the brain may help to prevent Alzheimer's and other neurological diseases, according to a study published today in Nature Biomedical Engineering.

31 May 2025

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

People who are at higher risk for heart disease also seem more likely to develop dementia.

30 May 2025

Sleep disorders predict dementia risk years before diagnosis, study shows

Researchers analyzed health records from over 1 million people in Finland, Wales, and the UK to assess the long-term impact of sleep disorders on neurodegenerative diseases. They found that diagnosed sleep disorders can predict Alzheimer’s, Parkinson’s, and dementia risk up to 15 years before symptoms, regardless of genetic predisposition.

28 May 2025

Decade-long brain study offers new insights into aging

Researchers from The University of Texas at Dallas' Center for Vital Longevity (CVL) have released the full dataset from a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline.

28 May 2025

Study highlights barriers to Alzheimer’s care in rural Georgia

Rural Georgians may find it difficult to access medication that could slow the progression of Alzheimer's disease, according to a new study from the University of Georgia.

28 May 2025

Traditional South Asian medicinal plants show promise in addressing memory disorders

The growing global population of elderly individuals has led to a dramatic rise in chronic diseases, including neurocognitive disorders such as Alzheimer's disease.

27 May 2025

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

A large Swedish cohort study found that elevated blood biomarkers associated with Alzheimer’s disease—including p-tau217, p-tau181, neurofilament light chain, and GFAP—predict accelerated muscle strength decline over 12 years in dementia-free older adults. These findings suggest that early identification of Alzheimer’s-related biomarkers could help clinicians intervene sooner to prevent sarcopenia and related adverse outcomes in aging populations.

27 May 2025

Blood test pinpoints early Alzheimer’s risk with high accuracy

Researchers evaluated a fully automated plasma biomarker panel to detect early amyloid-β accumulation in cognitively unimpaired adults at risk for Alzheimer’s disease. Plasma p-tau217/Aβ42 emerged as the most robust and accurate blood-based marker for identifying preclinical amyloid pathology.

26 May 2025

Alzheimer's Disease News and Research

Further Reading

Late-life mood disorders may signal neurodegenerative diseases

Blood test shows high accuracy in detecting Alzheimer's disease

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's gene therapy could help protect the brain from damage and preserve cognitive function

Integrating discoveries with translational science to transform Alzheimer's care

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Pitt researchers challenge a decades-old assumption about brain plasticity

MIND diet linked to lower risk of dementia across diverse populations

Older adults accurately gauge their financial skills until dementia sets in

Molecular stress makes old neurons vulnerable to neurodegenerative diseases

New discovery reveals immune molecule’s role in Alzheimer’s disease

Epileptic seizures more common in frontotemporal dementia patients than previously known

New wearable device monitors brain waste clearance during sleep

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

Sleep disorders predict dementia risk years before diagnosis, study shows

Decade-long brain study offers new insights into aging

Study highlights barriers to Alzheimer’s care in rural Georgia

Traditional South Asian medicinal plants show promise in addressing memory disorders

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

Blood test pinpoints early Alzheimer’s risk with high accuracy

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