Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Sunovion Pharmaceuticals Inc. today announced post-hoc analysis results of a positive Phase 3 placebo-controlled clinical study, as well as interim data from a long-term open-label extension study evaluating Latuda (lurasidone HCI) in children and adolescents (10 to 17 years of age) with major depressive episodes associated with bipolar I disorder (bipolar depression).

28 Oct 2017

Case report of a 21 year old woman sweating blood

She had a rare condition called hematohidrosis where she was sweating blood and her tears too contained blood. The dermatologists published the report of her rare case while protecting her identity, this week in the Canadian Medical Association Journal.

24 Oct 2017

Increasing the dosage of antidepressants does not carry benefits, analysis reveals

In the current issue of Psychotherapy and Psychosomatics a new analysis discloses that increasing the dosage of antidepressant drugs does not carry benefits. As many patients with unipolar depression do not respond sufficiently to initial antidepressant monotherapy, a dose increase of the current administered antidepressant (dose escalation, high-dose treatment) is frequently carried out as next treatment measure.

24 Oct 2017

New analysis reveals insights into long-term effects of antidepressant drugs

In the current issue of Psychotherapy and Psychosomatics a new analysis discloses insights into the long term effects of antidepressant drugs. Major depressive disorder (MDD) is more often chronic or recurrent in clinical than in community samples.

24 Oct 2017

Trial compares long-term effects of psychotherapy and antidepressants on depression symptoms

In the current issue of Psychotherapy and Psychosomatics there are data about the long term-effects of a form of psychotherapy in depression compared to medication.

24 Oct 2017

Antidepressant use in children, adolescents linked to increased risk of type 2 diabetes

A team of researchers from the University of Maryland School of Pharmacy and the University of Maryland School of Medicine found that current (prolonged) use of serotonin reuptake inhibitors – a major class of antidepressant medications – in children and adolescents was associated with a nearly two-fold increased risk of developing type 2 diabetes when compared to youths who formerly used (but eventually discontinued) those medications.

24 Oct 2017

Four genes associated with OCD identified

There are found genes that have been identified to be associated with obsessive compulsive disorder (OCD). These genes have been found to alter the circuitry of the brain in a manner that could lead to OCD. These genetic links also point to the fact why OCD sometimes runs in families. The study is published in the latest issue of Nature Communications.

18 Oct 2017

On back roads of Appalachia’s coal country, mental health services are as rare as jobs

Every other month, Tanya Nelson travels 32 miles from the heart of Appalachia's coal country for an appointment with the nearest psychiatrist for therapy and to renew prescriptions. But the commute, which should take less than an hour through the winding mountain roads of southern West Virginia, consumes her entire day.

17 Oct 2017

Magic mushrooms may effectively reset activity of brain circuits involved in depression

Patients taking psilocybin to treat depression show reduced symptoms weeks after treatment following a 'reset' of their brain activity.

13 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

Study unveils neuronal effects of psychedelics using cerebral organoids

A Brazilian study, published in Scientific Reports on October 09, 2017, has identified changes in signaling pathways associated with neural plasticity, inflammation and neurodegeneration triggered by a compound from the family of dimethyltryptamine known as 5-MeO-DMT.

9 Oct 2017

Research confirms smartphone apps as effective treatment option for depression

New Australian-led research has confirmed that smartphone apps are an effective treatment option for depression, paving the way for safe and accessible interventions for the millions of people around the world diagnosed with this condition.

22 Sep 2017

Study may provide insights into treating autism and other neuropsychiatric disorders

Alterations in a naturally occurring chemical in the brain called serotonin have been linked to a number of neuropsychiatric disorders including depression, anxiety, obsessive-compulsive disorder as well as autism spectrum disorder (ASD).

20 Sep 2017

Sleep deprivation rapidly reduces depression symptoms in nearly half of depressed patients

Sleep deprivation -- typically administered in controlled, inpatient settings -- rapidly reduces symptoms of depression in roughly half of depression patients, according the first meta-analysis on the subject in nearly 30 years, from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Sep 2017

Study investigates depression treatment among older people with dementia

A high prevalence of depression among older individuals with dementia is prompting researchers at the University of Arizona College of Pharmacy and Banner Alzheimer's Institute to investigate depression treatment among this population.

19 Sep 2017

Antidepressant users have higher risk of death than non-users, researchers find

Antidepressant medications, most commonly prescribed to reduce depression and anxiety, increase the risk of death, according to new findings by a McMaster-led team of researchers.

14 Sep 2017

Tulane researchers move closer to improving treatment for chronic depression

In a new study published in the journal Cell Reports, researchers associated with the Tulane Brain Institute say they have moved a step closer to improving treatment for chronic depression.

7 Sep 2017

Existing antidepressant drug could slow progression of Parkinson’s

Michigan State University scientists now have early proof that an antidepressant drug that's been around for more than 50 years could slow the progression of Parkinson's.

6 Sep 2017

Antidepressants used for chronic pain relief come with significant side effects

Chronic pain negatively impacts a person's quality of life. Often, over the counter pain medication, such as ibuprofen or aspirin, are ineffective in alleviating chronic pain. In these instances, a surprising choice is often a drug used to treat an entirely different condition - depression.

5 Sep 2017

Study: Low long-term use of psychiatric drugs does not appear to affect cognition in schizophrenia

A long-term study has found that low cumulative exposure to benzodiazepine and antidepressant medications does not seem to affect cognition in schizophrenia.

5 Sep 2017

Antidepressant News and Research

Further Reading

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Case report of a 21 year old woman sweating blood

Increasing the dosage of antidepressants does not carry benefits, analysis reveals

New analysis reveals insights into long-term effects of antidepressant drugs

Trial compares long-term effects of psychotherapy and antidepressants on depression symptoms

Antidepressant use in children, adolescents linked to increased risk of type 2 diabetes

Four genes associated with OCD identified

On back roads of Appalachia’s coal country, mental health services are as rare as jobs

Magic mushrooms may effectively reset activity of brain circuits involved in depression

Human minibrains expose psychedelic drug effects, study reveals

Study unveils neuronal effects of psychedelics using cerebral organoids

Research confirms smartphone apps as effective treatment option for depression

Study may provide insights into treating autism and other neuropsychiatric disorders

Sleep deprivation rapidly reduces depression symptoms in nearly half of depressed patients

Study investigates depression treatment among older people with dementia

Antidepressant users have higher risk of death than non-users, researchers find

Tulane researchers move closer to improving treatment for chronic depression

Existing antidepressant drug could slow progression of Parkinson’s

Antidepressants used for chronic pain relief come with significant side effects

Study: Low long-term use of psychiatric drugs does not appear to affect cognition in schizophrenia

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