DNA Sequencing News and Research

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NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

Researchers reveal totally new biological mechanism that underlies cancer

In a landmark study, researchers from the Broad Institute and Massachusetts General Hospital reveal a completely new biological mechanism that underlies cancer. By studying brain tumors that carry mutations in the isocitrate dehydrogenase (IDH) genes, the team uncovered some unusual changes in the instructions for how the genome folds up on itself.

13 Jan 2016

UCLA discovery could lead to new therapies for autism

UCLA scientists have discovered that an overlooked region in brain cells houses a motherlode of mutated genes previously tied to autism. Recently published in Neuron, the finding could provide fresh drug targets and lead to new therapies for the disorder, which affects one in 68 children in the United States.

13 Jan 2016

IMB scientists identify two proteins vital for demethylation of DNA

Scientists at the Institute of Molecular Biology in Mainz have identified a missing piece of the puzzle in understanding how epigenetic marks are removed from DNA. The research on DNA demethylation sheds new light on a fundamental process that is important in development and diseases such as cancer.

12 Jan 2016

Small differences in specific genetic variant could alter nicotine consumption

Nicotine is an addictive substance and genetic factors are known to play a role in smoking behaviors. Recently, a team of researchers at Penn State and the University of Colorado determined how small differences in a particular region of the mouse genome can alter nicotine consumption.

11 Jan 2016

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

Anthony Nolan has today launched a new tissue typing method that could significantly improve stem cell transplant outcomes.

8 Jan 2016

New Penn study shows that social behavior in carpenter ants can be reprogrammed

In Florida carpenter ant colonies, distinct worker castes called minors and majors exhibit pronounced differences in social behavior throughout their lives. In a new study published today in Science, a multi-institution team anchored at University of Pennsylvania found that these caste-specific behaviors are not set in stone.

4 Jan 2016

Researchers use dynamic time-series data to help improve accuracy of genome mapping

If you already have the sequenced map of an organism's genome but want to look for structural oddities in a sample, you can check the genomic barcode -- a series of distances between known, targeted sites -- by cutting a DNA sequence at those sites and examining the distance between the cuts.

30 Dec 2015

Scientists identify 52 genetic variations associated with age-related macular degeneration

In one of the latest examples of precision medicine, teams of geneticists from nine countries, involving more than 100 scientists, analyzed the genes of more than 33,000 individuals in the hope of finding genetic variations responsible for age-related macular degeneration (AMD), the leading cause of vision loss among people age 50 or older.

22 Dec 2015

New easy-to-use computer program can quickly identify drug-resistant infections

Scientists have developed an easy-to-use computer program that can quickly analyse bacterial DNA from a patient's infection and predict which antibiotics will work, and which will fail due to drug resistance. The software is currently being trialled in three UK hospitals to see whether it could help speed up diagnosis of drug-resistant infections and enable doctors to better target the prescription of antibiotics.

21 Dec 2015

New study sheds light on the molecular basis of memory and learning

The brain still harbours many unknowns. Basically, it is assumed that it stores experiences by altering the connections between brain cells. This ability to adapt - which is also called "plasticity" - provides the basis for memory and learning, which is the ability to draw conclusions from memories. On a molecular scale these changes are mediated by modifications of expression of specific genes that as required strengthen or weaken the connections between the brain cells.

18 Dec 2015

A glass of clean drinking water contains 10 million bacteria

Researchers from Lund University in Sweden have discovered that our drinking water is to a large extent purified by millions of "good bacteria" found in water pipes and purification plants. So far, the knowledge about them has been practically non-existent, but this new research is about to change that.

17 Dec 2015

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

Embryos require adequate amounts of energy so that they can successfully progress through each of their cell divisions.

16 Dec 2015

New study finds a reason for ethnic disparity in CF diagnoses

Cystic fibrosis (CF) occurs less frequently in nonwhites than in whites, and nonwhites tend to be diagnosed at a later age. This late diagnosis often comes only once they have become symptomatic, rather than through newborn screening programs or molecular diagnostic testing.

16 Dec 2015

Stanford researchers develop novel technique for mapping diversity of gut bacteria

A collaboration between computer scientists and geneticists at Stanford University has produced a novel technique for mapping the diversity of bacteria living in the human gut.

15 Dec 2015

ICGC article lays foundation for the coming era of cancer genomic research

An eye-opening article from the International Cancer Genome Consortium was published today in the prestigious journal Nature Communications. It lays a foundation for the coming era of research in cancer genomics.

13 Dec 2015

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Oncologists are increasingly using information obtained from investigations of the tumor genome in order to find individualized therapies for patients. They specifically search the hereditary information of cancer cells for mutations that drive malignant growth. By now, targeted drugs against many of these cancer-typical cellular alterations have become available.

11 Dec 2015

DNA Sequencing News and Research

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers reveal totally new biological mechanism that underlies cancer

UCLA discovery could lead to new therapies for autism

IMB scientists identify two proteins vital for demethylation of DNA

Small differences in specific genetic variant could alter nicotine consumption

Anthony Nolan introduces new tissue typing method that could revolutionise stem cell transplantation

New Penn study shows that social behavior in carpenter ants can be reprogrammed

Researchers use dynamic time-series data to help improve accuracy of genome mapping

Scientists identify 52 genetic variations associated with age-related macular degeneration

New easy-to-use computer program can quickly identify drug-resistant infections

New study sheds light on the molecular basis of memory and learning

A glass of clean drinking water contains 10 million bacteria

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

New study finds a reason for ethnic disparity in CF diagnoses

Stanford researchers develop novel technique for mapping diversity of gut bacteria

ICGC article lays foundation for the coming era of cancer genomic research

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Stanford researchers invent new technique to dramatically accelerate protein evolution

Research reveals genetic variants linked to treatment-related complications in children with blood diseases

TGen, Barrow researchers identify genetic risk factors linked to stress-induced cardiomyopathy

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