Electron Microscopy News and Research

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Super-immunity in a camelid extensively immunized with the SARS-CoV-2 receptor-binding domain

A recent study published in Cell Reports reported the development of pan-sarbecovirus nanobodies (psNbs).

10 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Using advanced microscopy techniques, researchers at Karolinska Institutet and Stockholm University in Sweden have visualized in unprecedented detail the machinery that the cells' powerhouses, the mitochondria, use to form their proteins.

8 Jun 2022

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Scientists have, for the first time, revealed at the atomic level the structure of a protein that carries one of the body's most important neurotransmitters into neurons.

8 Jun 2022

New diagnostic procedure could help start optimal stroke treatment in a timely manner

A blood clot in the brain that blocks the supply of oxygen can cause an acute stroke. In this case, every minute counts.

8 Jun 2022

Open multiplexing with Cell DIVE offers cancer researchers more choices

Leica has introduced a new generation of its multiplexed imaging solution, Cell DIVE, including software and hardware improvements. The more scalable and efficient multiplexing platform addresses spatial cell biology and function within the tissue microenvironment

From Leica Microsystems GmbH 8 Jun 2022

Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Researchers identified 10-40, a human monoclonal antibody with potent neutralizing activity against SARS-CoV, SARS-CoV-2, and related sarbecoviruses.

30 May 2022

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the journal Cell Reports.

27 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Cryogenic electron microscopy used to determine the structure of fungal ribosome

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

UAB researchers track the behavior of microplastics inside a living organism

A UAB research team has managed to track the behavior of microplastics during their "journey" through the intestinal tract of a living organism and illustrate what happens along the way.

23 May 2022

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Researchers explored whether surface ACE2 carried by EVs can facilitate the entry of SARS-CoV-2 into host cells.

20 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers predict structure models of the full-length SARS-CoV-2 N protein in both the presence and absence of RNA.

19 May 2022

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Researchers assessed the vaccine-induced humoral responses against SARS-CoV-2 post four different vaccination regimens comprising homologous and heterologous vaccine doses.

18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

Electron Microscopy News and Research

Super-immunity in a camelid extensively immunized with the SARS-CoV-2 receptor-binding domain

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Discovery of small protein’s structure could lead to new therapies for neurological disorders

New diagnostic procedure could help start optimal stroke treatment in a timely manner

Open multiplexing with Cell DIVE offers cancer researchers more choices

Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Cryogenic electron microscopy used to determine the structure of fungal ribosome

New imaging approach helps scientists build a complete picture of brain networks

UAB researchers track the behavior of microplastics inside a living organism

Exploring the possibility of whether surface ACE2 carried by extracellular vesicles can facilitate SARS-CoV-2 infection

Plastins may promote disease when they act like workaholics and disrupt cellular environment

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Combined COVID-19 vaccination regimen found to induce more potent anti-SARS-CoV-2 antibodies

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

Researchers develop treatment that suppresses mutational escape of SARS-CoV-2

Broad-spectrum polymeric antivirals against SARS-CoV-2

Why do diabetic patients have more severe SARS-CoV-2 infections?

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo