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Royal College of Pathologists‘ bulletin provides summary of Tissue Handling Workshop

A recent article in the Royal College of Pathologists‘ bulletin provides a summary of our recent Tissue Handling Workshop.

From Genomics England 20 Mar 2018

TSRI scientists discover new pathway to promote mitochondrial function during stress

Scientists at The Scripps Research Institute have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

15 Mar 2018

Researchers create cardiomyocyte molds to mend broken hearts

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

13 Mar 2018

Transformative new approach for viral titer determination using xCELLigence RTCA

Accurate determination of viral titers is critical to vaccine development. Historically, titers have been determined using endpoint assays which are labor-intensive, expensive, and time-consuming. This is increasingly problematic in modern production facilities where bioprocess optimization is performed using high-throughput cell culture reactors that can produce batches of virus faster than they can be analyzed.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

A new study performed in the Netherlands has linked exposure to residential air pollution during fetal life with brain abnormalities that may contribute to impaired cognitive function in school-age children. The study, published in Biological Psychiatry, reports that the air pollution levels related to brain alterations were below those considered to be safe.

8 Mar 2018

Home-based semen analysis kit could provide rapid, cost-effective way to test male fertility

It is estimated that of the 70 million cases of infertility worldwide, almost half are caused by factors relating to the male partner. A number of semen parameters – motility, morphology, velocity, volume, concentration, and count – affect male fertility.

28 Feb 2018

New military vehicle shock absorbing device may protect troops from blast-induced TBI

Researchers from theUniversity of Maryland School of Medicine and the University of Maryland A. James Clark School of Engineering have developed a new military vehicle shock absorbing device that may protect troops from traumatic brain injury (TBI) after a land mine blast.

27 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Bioactive compound limits collateral damage in the kidneys after heart attack

A heart attack triggers an acute inflammatory response at the damaged portion of the heart's left ventricle. If this acute inflammation lingers, it can lead to stretching of the ventricle and heart failure. The inflammation can claim another victim -- the kidneys.

21 Feb 2018

Scientists program nanorobots to shrink tumors

In a major advancement in nanomedicine, Arizona State University scientists, in collaboration with researchers from the National Center for Nanoscience and Technology, of the Chinese Academy of Sciences, have successfully programmed nanorobots to shrink tumors by cutting off their blood supply.

12 Feb 2018

Scientists gain better understanding of how the intestine repairs itself after injury

Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues in the human body, repairs itself after injury caused by intestinal rotavirus infection.

30 Jan 2018

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery-; successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

Scientists introduce air-filled microbubbles as intravenous oxygen carriers

Severe oxygen deficiency eventually leads to cardiac arrest. If the blood’s oxygen content cannot be rapidly re-established, the patient may die within minutes. In the journal Angewandte Chemie, American scientists have introduced air-filled microbubbles that could be used as an intravenous oxygen carrier to increase the survival rate of such patients. Because they rapidly dissolve in blood, the risk of embolism is minimal.

24 Jan 2018

New genomic tools provide better understanding of the human immune system

When the body is under attack from pathogens, the immune system marshals a diverse collection of immune cells to work together in a tightly orchestrated process and defend the host against the intruders.

22 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Zinc present in semen determines male fertility, study shows

Trace levels of zinc present in semen is a vital determinant of male fertility, a recent study in Bangladesh capital Dhaka concludes.

19 Dec 2017

Russian researchers create new approaches to prevention and treatment of diabetes

A team of scientists from the Ural Federal University and the Institute of Immunology and Physiology modeled type 1 diabetes in an experiment to study recovery processes in the pancreas.

11 Dec 2017

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Phasefocus continues to increase its global international profile with the appointment of Nuohai Life Sciences as the company’s exclusive distributor for mainland China, Hong Kong and Macau.

From Phase Focus Limited 11 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Morphology News and Research

Royal College of Pathologists‘ bulletin provides summary of Tissue Handling Workshop

TSRI scientists discover new pathway to promote mitochondrial function during stress

Researchers create cardiomyocyte molds to mend broken hearts

Transformative new approach for viral titer determination using xCELLigence RTCA

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

Home-based semen analysis kit could provide rapid, cost-effective way to test male fertility

New military vehicle shock absorbing device may protect troops from blast-induced TBI

Zika virus could be alternative for treatment of aggressive brain cancer

Bioactive compound limits collateral damage in the kidneys after heart attack

Scientists program nanorobots to shrink tumors

Scientists gain better understanding of how the intestine repairs itself after injury

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists introduce air-filled microbubbles as intravenous oxygen carriers

New genomic tools provide better understanding of the human immune system

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Zinc present in semen determines male fertility, study shows

Russian researchers create new approaches to prevention and treatment of diabetes

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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