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New green, economical way achieves key organic synthesis via catalyst synergy

In organic chemistry, discovering new reactions is one thing, but to carry them off efficiently is quite another. Carbon-carbon bond-forming is at the heart of organic synthesis, allowing us to stitch together diverse functional groups into an endless array of useful compounds.

26 Feb 2019

Testosterone is not the only hormone needed for penis development

A new study has revealed that in addition to testosterone, the masculinization process involves a hormone called androsterone, which originates in other tissues.

15 Feb 2019

Researchers design new protocol to improve reproduction of ovine cattle

Researchers of the Veterinary Faculty of the CEU Cardenal Herrera University and the National Institute of Farming and Food Research and Technology have designed a new protocol to synchronize heats and ovulation periods to improve the reproduction of ovine cattle, which is based on the use of natural hormones.

13 Feb 2019

Phthalates may decrease fertility in female mice, study finds

A phthalate found in many plastic and personal care products may decrease fertility in female mice, a new study found.

8 Feb 2019

Study: Maternal age, body mass index, race affect hormone concentrations in pregnancy

Hormone concentrations during early fetal development -- that may affect the child's development and increase the mother's risk for breast and ovarian cancer years later -- are significantly affected by maternal age, body mass index and race rather than lifestyle, according to a Rutgers study.

5 Feb 2019

Low-calorie diet prevents asthma symptoms in mice, study finds

Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet’s fat and sugar content.

31 Jan 2019

Study: Low-calorie diet prevented asthma symptoms in mice

Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet's fat and sugar content.

31 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

Unique form of chronic sinusitis found in older patients

Older patients with a diagnosis of chronic sinusitis -- a disease of the nasal cavity and paranasal sinuses that often persists over many years -- have a unique inflammatory signature that may render them less responsive to steroid treatment, according to a new study published by Vanderbilt researchers.

23 Jan 2019

Low-salt diet may be more beneficial for females than males

A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.

11 Dec 2018

How body image concerns in young men contribute to increase in hospital cases

"Recent media reports highlighting NHS statistics which show a rapid increase in the number of boys and young men being admitted to hospital suffering from eating disorders are welcome, if only for helping to draw attention to this issue.

4 Dec 2018

Anabolic steroids may increase risk of early death in men

Men who use androgenic anabolic steroids—such as testosterone—may face a higher risk of early death and of experiencing more hospital admissions, according to a new Journal of Internal Medicine study.

21 Nov 2018

Pooled analysis of Intersect ENT's steroid releasing implants in patients after frontal sinus surgery to be published

Intersect ENT, Inc., a company dedicated to transforming care for patients with ear, nose and throat conditions, today announced publication of a pooled analysis in the International Forum of Allergy & Rhinology, the official journal of the American Rhinologic Society, of the company's PROPEL Contour and PROPEL Mini steroid-releasing sinus implants showing improved outcomes of frontal sinus surgery.

16 Nov 2018

Researchers find a class of drug that could be promising treatment for uveitis

Ocular inflammation uveitis is a serious disease that can destroy eye tissue and cause irreversible blindness.

2 Nov 2018

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Bristol-Myers Squibb Company today announced four-year data from the Phase 3 CheckMate -067 clinical trial - the longest follow-up to date - which continues to demonstrate durable, long-term survival benefits with the first-line combination of Opdivo (nivolumab) and Yervoy (ipilimumab), versus Yervoy alone, in patients with advanced melanoma.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

Fight for Sight chooses World Sight Day 2018 to announce funding for glaucoma research

Fight for Sight has chosen World Sight Day 2018 to announce funding for a research project that will develop personalized medicine for patients at risk of glaucoma from steroid use.

12 Oct 2018

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

Lyra Therapeutics, Inc., a clinical-stage biotechnology company developing medicines precisely designed to target ear, nose and throat diseases, today announced the presentation of Phase 1 clinical data for the company's lead therapeutic, LYR-210, for chronic rhinosinusitis, a debilitating disease caused by inflammation of the paranasal sinus tissues that affects approximately 27 million people, or 11% of the adult population in the U.S.

8 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Steroid News and Research

New green, economical way achieves key organic synthesis via catalyst synergy

Testosterone is not the only hormone needed for penis development

Researchers design new protocol to improve reproduction of ovine cattle

Phthalates may decrease fertility in female mice, study finds

Study: Maternal age, body mass index, race affect hormone concentrations in pregnancy

Low-calorie diet prevents asthma symptoms in mice, study finds

Study: Low-calorie diet prevented asthma symptoms in mice

Scientists pinpoint mechanism that leads to steroid diabetes

Unique form of chronic sinusitis found in older patients

Low-salt diet may be more beneficial for females than males

How body image concerns in young men contribute to increase in hospital cases

Anabolic steroids may increase risk of early death in men

Pooled analysis of Intersect ENT's steroid releasing implants in patients after frontal sinus surgery to be published

Researchers find a class of drug that could be promising treatment for uveitis

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Fight for Sight chooses World Sight Day 2018 to announce funding for glaucoma research

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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