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SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

A new study describes the varying ways in which the virus co-opts the machinery of the host cell following infection to evade or modulate the host immune response, alter the pattern of translation of viral proteins, and the release of new viral particles.

24 Jun 2021

Researchers identify the origins of seven types of kidney cancer

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology and Oncode Institute.

24 Jun 2021

Researchers uncover new function of regulator protein in multiple myeloma development

A specific regulatory protein significantly influences the development of tumor-inducing blood vessels in the bone marrow of blood cancer patients.

24 Jun 2021

Machine-learning approach could accurately predict the evolution of breast cancer

From amoebas to zebras, all living things evolve. They change over time as pressures from the environment cause individuals with certain traits to become more common in a population while those with other traits become less common.

24 Jun 2021

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it.

23 Jun 2021

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Increased severity of COVID-19 in pregnancy

A new preprint on the medRxiv* server provides more evidence that COVID-19 likely causes a more serious phenotype to arise in pregnant women.

23 Jun 2021

Blood test shows promise for predicting treatment response in patients with advanced HPV-positive throat cancer

A sensitive blood test being developed by a team of researchers at the University of Michigan Rogel Cancer Center shows promise for predicting whether patients with metastatic HPV-positive throat cancer will respond to treatment months earlier than standard imaging scans.

23 Jun 2021

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

22 Jun 2021

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor of physiology & biophysics and member of the Institute for Immunology at the University of California, Irvine.

22 Jun 2021

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

How do you kill tumor cells that can't be targeted? Get their more susceptible neighbors to help.

22 Jun 2021

Eating prunes daily can improve risk factors for cardiovascular disease in postmenopausal women

New research published in the Journal of Medicinal Food suggests eating prunes each day can improve risk factors for cardiovascular disease (CVD) including raising antioxidant capacity and reducing inflammation among healthy, postmenopausal women.

22 Jun 2021

LegoChem Biosciences and Iksuda Therapeutics expand License Agreement for development of antibody-drug conjugates

Iksuda Therapeutics today announced that it has expanded its research collaboration and License Agreement with LegoChem Biosciences, Inc.

From Iksuda Therapeutics 22 Jun 2021

FLASH radiotherapy could revolutionize future tumor treatments

It could become a breakthrough for future tumor treatments with heavy ions and pave new ways: In the current experiment period FAIR-Phase 0, the GSI Helmholtzzentrum für Schwerionenforschung and the future accelerator center FAIR succeeded in performing a carbon ion FLASH experiment for the first time.

21 Jun 2021

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

Hypoxia, or the inadequate oxygenation of a tissue, is a condition occurring frequently in all solid tumors such as melanoma skin cancer.

21 Jun 2021

New breakthrough could lead to a cure for common childhood cancer

Scientists studying a common childhood cancer have made a major breakthrough which could lead to a cure for some youngsters who would not have survived the condition.

21 Jun 2021

Blood test may help identify risk of bladder cancer recurrence after surgery

A blood test that can detect tiny amounts of circulating cancer DNA may be able to identify risk of cancer recurrence and guide precision treatment in bladder cancer following surgery, according to a clinical study led byProfessor Tom Powles from Queen Mary University of London andBarts Health NHS Trust.

21 Jun 2021

Tumor News and Research

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Researchers identify the origins of seven types of kidney cancer

Researchers uncover new function of regulator protein in multiple myeloma development

Machine-learning approach could accurately predict the evolution of breast cancer

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

Increased severity of COVID-19 in pregnancy

Blood test shows promise for predicting treatment response in patients with advanced HPV-positive throat cancer

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

Eating prunes daily can improve risk factors for cardiovascular disease in postmenopausal women

LegoChem Biosciences and Iksuda Therapeutics expand License Agreement for development of antibody-drug conjugates

FLASH radiotherapy could revolutionize future tumor treatments

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

New breakthrough could lead to a cure for common childhood cancer

Blood test may help identify risk of bladder cancer recurrence after surgery

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

New research uncovers substantial differences in rates of childhood cancers

New hydrogel-based electrodes snugly conform to the body’s myriad shapes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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