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Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

22 Jun 2023

Repurposing cancer drugs for malaria treatment

With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.

21 Jun 2023

Researchers take promising step forward in the battle against HIV

A multi-institutional research group led by researchers from Tokyo Medical and Dental University (TMDU) has made a significant and promising step forward in our ability to treat human immunodeficiency virus type 1 (HIV-1), the virus underlying acquired immunodeficiency syndrome (AIDS).

21 Jun 2023

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

Low-level laser therapy and associated photobiomodulation is the most effective treatment for tinnitus

Low-level laser therapy and associated photobiomodulation is the most effective of the known treatments for tinnitus, according to a study comparing the main therapies in current use, conducted by Brazilian scientists affiliated with the Optics and Photonics Research Center.

21 Jun 2023

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

A single mutation stands in the way of a drug's effectiveness. Understanding it helps find new therapeutic approaches.

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Study removes AMR plasmids using a mobile, broad-host-range CRISPR-Cas9 delivery tool.

21 Jun 2023

Antidepressant prescriptions may reduce the risk of testing positive for COVID-19

New research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has found that community mental health patients who were prescribed antidepressants were significantly less likely to test positive for COVID-19 when admitted to inpatient care.

20 Jun 2023

$3.3M HHS grant supports UTHealth Houston study on combination treatment strategy for pancreatic cancer

A combination strategy of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with chemotherapy for pancreatic cancer will be studied at UTHealth Houston through a $3.3 million grant from the National Cancer Institute by the U.S. Department of Health and Human Services.

20 Jun 2023

Study reveals patterns of high blood pressure in pregnant women, linked to maternal health risks

Research examines the trajectory of systolic blood pressure in pregnant women and its associations with various factors. It sheds light on the patterns and risks related to blood pressure during pregnancy.

20 Jun 2023

UTHSC researchers receive major national award to find new treatments for breast cancer metastasis

UTHSC researchers working to find new treatments to combat breast cancer metastasis recently pulled in a major national award.

20 Jun 2023

New treatment could be instrumental in restoring the blood-brain barrier's normal function

There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the brain's precious gray matter.

20 Jun 2023

Researchers develop a prediction tool for blood cancer therapies

Since its introduction in 2015, a prediction tool developed by the European Society of Medical Oncology has been providing support worldwide in the assessment of the clinical benefits of new cancer therapies.

20 Jun 2023

Older people do not know enough about the risks associated with drinking alcohol, research shows

A large proportion of older people state that they drink alcohol twice a week or more and the difference in alcohol use between men and women is getting smaller, according to researchers at the University of Agder.

20 Jun 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

Researchers aimed to understand the association between wine consumption and cardiovascular health.

20 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Researchers create a detailed map of neurotransmitter receptors that control information flow

Receptor patterns define key organizational principles in the brain, scientists have discovered.

19 Jun 2023

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

Announcing a new article publication for Zoonoses journal. Non-typhoidal Salmonella (NTS) is a major cause of human salmonellosis globally. Food animals are major NTS reservoirs.

19 Jun 2023

Drugs News and Research

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Repurposing cancer drugs for malaria treatment

Researchers take promising step forward in the battle against HIV

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Low-level laser therapy and associated photobiomodulation is the most effective treatment for tinnitus

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Antidepressant prescriptions may reduce the risk of testing positive for COVID-19

$3.3M HHS grant supports UTHealth Houston study on combination treatment strategy for pancreatic cancer

Study reveals patterns of high blood pressure in pregnant women, linked to maternal health risks

UTHSC researchers receive major national award to find new treatments for breast cancer metastasis

New treatment could be instrumental in restoring the blood-brain barrier's normal function

Researchers develop a prediction tool for blood cancer therapies

Older people do not know enough about the risks associated with drinking alcohol, research shows

CBD and THC: promising remedies for aluminum-related neurological damage

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

Battle against RSV: Computational design paves way for new polyvalent vaccine

Researchers create a detailed map of neurotransmitter receptors that control information flow

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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