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Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.

2 Jun 2023

No measurable progress made in the last decade to reduce premature births, UN report reveals

No measurable progress has been made in any region of the world in the last decade to reduce the number of babies born prematurely and thus vulnerable to loss of life, a major UN report reveals.

2 Jun 2023

When Spectrometry bridges the gap between Proteomics and Biology

In this new episode of omg OMx, Kate Sumpo talks to Balyn Zaro about her research, experiences, and insights as a biologist in proteomics and spectrometry.

From Bruker Daltonics 2 Jun 2023

Is there an association being plant-based diets and mental health?

Researchers determined the relationship between plant-origin diet indices and mental health disorders

2 Jun 2023

How does a riboswitch regulate its own synthesis?

To prevent a global health crisis, scientists around the world are searching for ways to fight bacteria that can evade the current arsenal of antibiotics.

2 Jun 2023

Scientists investigate how immune system's T cells could fight many coronaviruses at once

Scientists at La Jolla Institute for Immunology (LJI) are investigating how the immune system's T cells react to a wide variety of coronaviruses, ranging from SARS to common cold coronaviruses.

1 Jun 2023

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

1 Jun 2023

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023

New algorithm could improve the search for genetic cause of hereditary diseases

So far, it has not been possible to explain the causes of around half of all rare hereditary diseases. A Munich research team has developed an algorithm that predicts the effects of genetic mutations on RNA formation six times more precisely than previous models.

1 Jun 2023

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Researchers evaluated the potential of three licorice (Glycyrrhiza) species, i.e., G. glabra (GG), G. uralensis (GU), and G. infata (GI), and hops (Humulus lupulus), and their main bioactive polyphenols, to prevent breast malignancy.

1 Jun 2023

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Researchers evaluated immune responses to COVID-19 BNT162b2 mRNA vaccinations among Indigenous Australian First Nations (FN) individuals by comorbidity and ethnicity.

1 Jun 2023

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Researchers evaluated titers and types of severe acute respiratory syndrome coronavirus 2 antibodies in voluntary blood donors.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Taurine and black pepper, along with key terpene constituents, are investigated for their potential in reducing cardiovascular risk factors and combating related diseases in this comprehensive literature review. Their cardioprotective effects and mechanisms are explored.

31 May 2023

Protein C News and Research

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Researchers characterize a unique molecular mechanism of early stages of programmed cell death

No measurable progress made in the last decade to reduce premature births, UN report reveals

When Spectrometry bridges the gap between Proteomics and Biology

Is there an association being plant-based diets and mental health?

How does a riboswitch regulate its own synthesis?

Scientists investigate how immune system's T cells could fight many coronaviruses at once

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

New algorithm could improve the search for genetic cause of hereditary diseases

Study suggests licorice-derived liquiritigenin has breast cancer prevention potential for high-risk postmenopausal women

Key insights into immune responses after COVID-19 vaccination in Indigenous people

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Multi-ethnic genome study unlocks new genetic links to health conditions

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Unique combination of intestinal bacteria in Japanese centenarians may be the key to long life

Study unlocks insights into how 'good fat' tissue could be harnessed to combat obesity, diabetes

Protein discovery could open up new treatment options for chronic kidney disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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