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Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

12 Oct 2020

CWRU and UH secure $4 million to establish research center focused on lung cancer in East Africa

Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute to establish an HIV-associated Malignancy Research Center (HAMRC) focused on lung cancer in East Africa.

9 Oct 2020

miR-29 is an age-dependent regulator of developmental plasticity in the visual cortex

Postnatal development of the brain after birth is characterized by temporary, function-specific windows of high plasticity (critical or sensitive periods).

9 Oct 2020

Study shows LED-based UV irradiation prevents bone and muscle loss in aging mice

A research team at Nagoya University in Japan has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass.

9 Oct 2020

Mathematical model helps investigate spaceflight mechanisms that induce cardiovascular deconditioning

Human spaceflight has been fascinating man for centuries, representing the intangible need to explore the unknown, challenge new frontiers, advance technology and push scientific boundaries further.

9 Oct 2020

WHO’s report may lead to greater awareness and deliver better eye health for all

Of the world's 7.8 billion people, 2.2 billion have impaired vision. Of this number, about half are treatable. In effect, they are one-eyed kings who are better off than the 39 million who are completely blind. Nevertheless, they are handicapped for normal living, as we gleaned from the first world report on vision by WHO.

9 Oct 2020

Higher HMBGB1 levels associated with obesity, inflammation, and cardiovascular disease in younger black adults

A "danger molecule" is higher in the blood of younger black adults than whites, females than males and increases with weight and age, researchers report in the first large, longitudinal study associating circulating HMGB1 levels with obesity, inflammation promoters and early indicators of cardiovascular risk in humans.

9 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

Researcher receives NIA grant to study traumatic stress-related accelerated cellular aging in the brain

Erika Wolf, PhD, clinical research psychologist for the National Center for PTSD at the VA Boston Healthcare System and associate professor of psychiatry at Boston University School of Medicine, is the recipient of a four-year, $1.7 million R01 award from the National Institute on Aging to study traumatic stress related accelerated cellular aging in the brain.

7 Oct 2020

Researchers receive NIH grant to investigate link between loneliness and Alzheimer's risk

Two researchers from The Neuro, with collaborators from the StoP-AD Centre at the Douglas Mental Health University Institute and the Quebec Artificial Intelligence Institute, will lead a research program centered on an emerging field of neuroscience thanks to a grant from the National Institutes of Health/National Institute of Aging in the USA.

7 Oct 2020

Lifetime experiences help older adults build resilience to pandemic trauma

Older adults are especially vulnerable physically during the coronavirus pandemic. But they're also notably resilient psychologically, calling upon a lifetime of experience and perspective to help them through difficult times.

7 Oct 2020

Study shows COVID-19 vulnerability increases exponentially with age

Aging-US recently published "From Causes of Aging to Death from COVID-19" by Blagosklonny et al. which reported that COVID-19 is not deadly early in life, but mortality increases exponentially with age - which is the strongest predictor of mortality.

7 Oct 2020

Nursing home residents face considerable risk when disasters strike

Government officials vastly undercounted the death toll among Florida nursing home residents after the destruction of Hurricane Irma in 2017, according to new research led by a Brown University scholar who studies disaster management in the long-term care industry.

6 Oct 2020

Deeper grief correlates with an overarching decline in quality of life, shows study

How will you cope with the death of your mother or spouse? Their death may disturb your concentration, causing accidents or lowering your productivity. Some bereaved cannot sleep, and others cannot get out of bed.

6 Oct 2020

Macrophage subgroups may play pivotal role in COVID-19 lethality

Many researchers are attempting to identify risk factors for severe or critical COVID-19. A recent paper in the journal Medical Hypotheses in September 2020 suggests that macrophage class activation is one of the factors that determine the clinical phenotype of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

5 Oct 2020

NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

Joe Verghese, M.B.B.S., M.S., , an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer's disease.

5 Oct 2020

Scientists discover small molecules that may reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer.

5 Oct 2020

New program results in shorter hospital stays, reduces post-surgery delirium in older adults

People age 65 years and older account for 40 percent of inpatient operations and one-third of outpatient procedures, and these older patients are more vulnerable to longer hospital stays and other complications after surgery than younger patients.

5 Oct 2020

Social isolation worsens the effects of Alzheimer's disease, study shows

A study in mice conducted by the UAB shows that social isolation worsens the effects of Alzheimer's disease, with hyperactivity levels reaching up to twice as much as in the pathology itself.

1 Oct 2020

Interactive tool can help people determine risk tolerance and risk factors of COVID-19

The Gerontological Society of America (GSA) -- the nation's largest interdisciplinary organization devoted to the field of aging -- has developed a COVID-19 decision aid to help people make an informed decision when they consider interacting with other people or taking part in activities outside their home.

1 Oct 2020

Aging News and Research

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

CWRU and UH secure $4 million to establish research center focused on lung cancer in East Africa

miR-29 is an age-dependent regulator of developmental plasticity in the visual cortex

Study shows LED-based UV irradiation prevents bone and muscle loss in aging mice

Mathematical model helps investigate spaceflight mechanisms that induce cardiovascular deconditioning

WHO’s report may lead to greater awareness and deliver better eye health for all

Higher HMBGB1 levels associated with obesity, inflammation, and cardiovascular disease in younger black adults

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Researcher receives NIA grant to study traumatic stress-related accelerated cellular aging in the brain

Researchers receive NIH grant to investigate link between loneliness and Alzheimer's risk

Lifetime experiences help older adults build resilience to pandemic trauma

Study shows COVID-19 vulnerability increases exponentially with age

Nursing home residents face considerable risk when disasters strike

Deeper grief correlates with an overarching decline in quality of life, shows study

Macrophage subgroups may play pivotal role in COVID-19 lethality

NIH awards $13.8 million to conduct studies on pre-dementia and Alzheimer's disease

Scientists discover small molecules that may reduce cellular stress

New program results in shorter hospital stays, reduces post-surgery delirium in older adults

Social isolation worsens the effects of Alzheimer's disease, study shows

Interactive tool can help people determine risk tolerance and risk factors of COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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