Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Novo Nordisk introduces new disposable prefilled insulin pen

Novo Nordisk has today announced the launch of their new disposable prefilled insulin pen - FlexTouch - in the UK. FlexTouch is available in the UK with Novo Nordisk's rapid-acting modern insulin analogue NovoRapid.

From Novo Nordisk 10 Oct 2011

Merck receives FDA approval for JUVISYNC to treat type 2 diabetes

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved JUVISYNC(sitagliptin and simvastatin), a new treatment for type 2 diabetes that combines the glucose-lowering medication sitagliptin, the active component of JANUVIA (sitagliptin), with the cholesterol-lowering medication ZOCOR.

10 Oct 2011

Scientists discover rare genetic alteration responsible for hypoglycaemia

Cambridge scientists have identified the cause of a rare, life-threatening form of hypoglycaemia. Their findings, which have the potential to lead to pharmaceutical treatments for the disorder, were published today, 07 October, in the journal Science.

7 Oct 2011

People with good vitamin D supply at lower risk of developing Type 2 diabetes

Scientists at the Helmholtz Zentrum München have shown that people with a good vitamin D supply are at lower risk of developing Type 2 diabetes mellitus. The study, which was conducted in cooperation with the German Diabetes Center and the University of Ulm, will be published in the October edition of the renowned scientific journal Diabetes Care.

4 Oct 2011

Working in shifts associated with elevated levels of stress hormone cortisol

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that shift work at a young age is associated with elevated long-term cortisol levels and increased BMI. Previous studies have shown that long-term elevated cortisol levels lead to increased abdominal obesity, hypertension, diabetes and cardiovascular risk.

3 Oct 2011

CCS Medical moves corporate headquarters to Farmers Branch, Texas

CCS Medical today announced the relocation of their corporate headquarters from Clearwater, Florida to Farmers Branch, Texas in the Dallas-Fort Worth Metroplex. CCS Medical has more than 1,500 employees in seven offices across the nation, and is a market leader in distributing home healthcare products and services to patients with chronic conditions in the United States.

1 Oct 2011

Vertex announces abstracts from hepatitis C program to be presented at The Liver Meeting

Vertex Pharmaceuticals Incorporated today announced that abstracts from its hepatitis C program, including two late-breaking posters from studies of INCIVEK (telaprevir) tablets and VX-222, were accepted for presentation at The Liver Meeting, the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in San Francisco, November 4-8, 2011.

1 Oct 2011

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes and obesity from being addressed successfully by novel drugs.

30 Sep 2011

Fat-rich 'western diet' fuels cardiovascular disease, type 2 diabetes and obesity

A major risk factor for cardiovascular disease, type 2 diabetes and other health- and life-threatening conditions, obesity is epidemic in the United States and other developed nations where it's fueled in large part by excessive consumption of a fat-rich "Western diet."

30 Sep 2011

GWAS uncovers new genes associated with type 1 diabetes

The largest-ever analysis of genetic data related to type 1 diabetes has uncovered new genes associated with the common metabolic disease, which affects 200 million people worldwide. The findings add to knowledge of gene networks involved in the origin of this complex disorder, in which patients depend on frequent insulin injections to control their blood sugar levels.

30 Sep 2011

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Stroke risk increases with even small rises in blood pressure

Small rises of blood pressure may greatly increase a person's risk of stroke, according to new research. The study review, published in the journal Neurology, analyzed the results of 12 studies on blood pressure and stroke incidences among a total of 518,520 adults.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Halozyme commences HTI-501 clinical trial for cellulite in women

Halozyme Therapeutics, Inc., a biopharmaceutical company developing and commercializing products targeting the extracellular matrix for the diabetes, cancer, dermatology and drug delivery markets, today announced the commencement of a Phase 1/2 clinical trial with HTI-501 (rHuCAT-L) in women with moderate to severe edematous fibrosclerotic panniculopathy (also known as cellulite).

28 Sep 2011

Aggressive glycemic control does not improve clinical outcomes for diabetic CABG patients

Surgeons from Boston Medical Center (BMC) have found that in diabetic patients undergoing coronary artery bypass graft (CABG) surgery, aggressive glycemic control does not result in any significant improvement of clinical outcomes as compared with moderate control.

28 Sep 2011

Asthmatic kids with type 1 diabetes have tougher time maintaining healthy sugar levels: Study

The reason why asthma might complicate pediatric diabetes care remains unclear, however, and is “something that needs to be explored more,” said Dr. Anita Swamy, a pediatric endocrinologist and medical director of the Chicago Children's Diabetes Center at La Rabida Children's Hospital in Chicago. She was not involved in the new study. The study appears in the October issue of Pediatrics.

27 Sep 2011

UCSF, QuantiaMD develop new DiabetesIQ mobile phone app

A new interactive mobile phone app called DiabetesIQ, released this week, challenges people to test their knowledge of diabetes and to compete with one another as they learn about the complexities of the disease, which affects more than 25 million Americans, including 4 million Californians.

27 Sep 2011

JDRF, iCo Therapeutics collaborate for iCo-007 Phase 2 trial in DME

iCo Therapeutics Inc. today announced that the company has entered into a research collaboration agreement with JDRF, the worldwide leader for research to cure, treat, and prevent type 1 diabetes (T1D), to support the previously announced Phase 2 investigator sponsored clinical trial investigating iCo-007 in Diabetic Macular Edema.

26 Sep 2011

Scientists reveal link between lipid cell dysfunction and metabolic diseases

By measuring the radioactive isotope carbon-14, scientists at Karolinska Institutet have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders.

26 Sep 2011

Parental motivation could improve diabetes management in high-risk youth

A little motivation for parents could go a long way toward improving young diabetes patients' ability to manage their own care, a Wayne State University researcher believes.

26 Sep 2011