Protein C News and Research

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NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

First-in-human clinical trial of liver dialysis device successfully completed

The first successful in-patient trial of liver dialysis* has been completed by researchers from UCL, the Royal Free Hospital, UCL spin-out Yaqrit and their collaborators.

31 May 2023

New variants of human metapneumovirus surge in Spain post-COVID, highlighting evolution and impact

Investigating Human metapneumovirus (HMPV) prevalence, genetic diversity, and evolution in respiratory tract infections (RTIs) for better understanding and management.

31 May 2023

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

An international team, led by UBC Okanagan researchers, suggests a simple tweak to the first meal of the day might help people living with Type 2 diabetes (T2D) better control their blood sugar levels.

31 May 2023

Important discovery could lead to new treatments for obesity and related diseases

Researchers at the University of East Anglia and the University of Cambridge have made an important discovery in the race to find treatments for obesity and related diseases, such as diabetes.

31 May 2023

Autoantibodies against 'synaptic adhesion protein' can cause schizophrenia-related changes

Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies.

31 May 2023

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Newborn babies who experience low levels of oxygen in their body tissues (hypoxia) due to sleep apnea, for example, tend to develop respiratory problems and hypertension (high blood pressure) in adulthood, and these problems may persist for the rest of their lives.

31 May 2023

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers from Japan fed isocaloric diets with varying amounts of protein to young and middle-aged male mice.

31 May 2023

Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that could delay or prevent pathophysiological changes that occur with AD.

31 May 2023

One-third of adults in the U.S. with Type 2 diabetes may have symptomless cardiovascular disease

1 in 3 adults with Type 2 diabetes may have undetected cardiovascular disease. Elevated levels of two protein biomarkers that indicate heart damage were associated with undetected or symptomless cardiovascular disease in adults with Type 2 diabetes compared to those without Type 2 diabetes, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

31 May 2023

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Scientists have identified a lipid-degrading enzyme as a prognostic biomarker for luminal breast cancer.

31 May 2023

UNIGE researchers identify how the influenza A virus manages to penetrate host cells

Influenza epidemics, caused by influenza A or B viruses, result in acute respiratory infection. They kill half a million people worldwide every year.

31 May 2023

CSEM collaborates with innovative Swiss start-up MOMM diagnostics to introduce revolutionary preeclampsia test

CSEM’s Tools for Life Sciences team is partnering with MOMM Diagnostics to develop a cutting-edge point-of-care solution for preeclampsia diagnostics. This ground-breaking multiplexed sensing device simultaneously detects two crucial biomarkers associated with this prevalent disease.

From CSEM 31 May 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Evidence supports a close link between Aβ, astrocyte reactivity, and tau pathology in preclinical AD.

31 May 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

North American arrival of A(H5N1) influenza raises concerns of potential pandemic outbreak

Rapid global expansion of highly pathogenic avian influenza A(H5N1) viruses in 2021, including reassortment with North American strains, highlights the need for proactive measures to combat their spread and mitigate the risk of a potential pandemic originating from these reassortants.

31 May 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Research finds more depressed patients with activated immune systems than previously estimated

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has used an assessment of gene expression involved in the immune response to show that there could be more patients with MDD with activated immune systems than research has previously estimated.

30 May 2023

Protein C News and Research

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

First-in-human clinical trial of liver dialysis device successfully completed

New variants of human metapneumovirus surge in Spain post-COVID, highlighting evolution and impact

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

Important discovery could lead to new treatments for obesity and related diseases

Autoantibodies against 'synaptic adhesion protein' can cause schizophrenia-related changes

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

One-third of adults in the U.S. with Type 2 diabetes may have symptomless cardiovascular disease

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

UNIGE researchers identify how the influenza A virus manages to penetrate host cells

CSEM collaborates with innovative Swiss start-up MOMM diagnostics to introduce revolutionary preeclampsia test

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

North American arrival of A(H5N1) influenza raises concerns of potential pandemic outbreak

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Research finds more depressed patients with activated immune systems than previously estimated

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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