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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

The flightless kakapo of New Zealand is in trouble. The world's heaviest parrot--representing one of the most ancestral branches of the parrot family tree--is nearly extinct, with barely 200 adults plodding the underbrush of four small islands.

29 Apr 2021

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer.

29 Apr 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases. The role of several lncRNAs in anti-viral inflammatory response regulation has recently been reported.

28 Apr 2021

A new concept for quickly detecting the presence of viruses

A Lancaster University professor has introduced a new concept for rapidly analysing for the presence of a virus from colds to coronaviruses.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

A detailed look at two cases of symptomatic COVID in vaccinated individuals

In a recent brief report published in the prestigious New England Journal of Medicine, researchers from the Rockefeller University in New York described a case of two fully vaccinated individuals in whom they found subsequent breakthrough infections with variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), carrying a number of substitutions of interest.

25 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

Study offers clues to clinical diagnosis of nephronophthisis in adults

Nephronophthisis (NPH) is a kidney disease affecting mainly children. Now, for the first time, researchers at Tokyo Medical and Dental University have studied a number of adults with NPH and highlighted clinical, genetic and pathological characteristics that could help in confirming this challenging diagnosis.

23 Apr 2021

Study links muscle gene to type 2 diabetes

People with type 2 diabetes tend to have poorer muscle function than others. Now a research team at Lund University in Sweden has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells.

23 Apr 2021

Researchers identify natural molecule that blocks the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally in abbreviated, low-dose immunization regimen.

23 Apr 2021

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location.

23 Apr 2021

Romantic relationships may play a role in mitigating the effects of trauma on student's drinking behavior

Students who have been exposed to interpersonal trauma - physical assault, sexual assault or unwanted sexual experiences - prior to college are more likely to engage in risky alcohol use.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

RNA secondary structures can contribute strongly to gene regulation, research shows

A team of scientists from Russia studied the role of double-stranded fragments of the maturing RNA and showed that the interaction between distant parts of the RNA can regulate gene expression. The research was published in Nature Communications.

22 Apr 2021

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Legislation currently under consideration in the U.S. Congress would increase regulatory oversight of certain diagnostic tests, and a new study by researchers at Massachusetts General Hospital (MGH) and colleagues from several other institutions demonstrates that its potential impact will depend on key details in the bill's final language.

22 Apr 2021

Experts to present latest research on aging and longevity at the 8th Aging Research & Drug Discovery Meeting

Scheibye-Knudsen Lab, University of Copenhagen and Deep Longevity are excited to reveal the speakers for the 8th Aging Research & Drug Discovery Meeting, the largest scientific academic, and industry conference that will transpire on August 31 - September 3, 2021, on-site at the Ceremonial Hall, University of Copenhagen, and online.

22 Apr 2021

DNA News and Research

Further Reading

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

Novel platform has potential to detect many disease-related biomarkers in just one test

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

A new concept for quickly detecting the presence of viruses

Researchers investigate how oxygen radicals protect against cancer

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

A detailed look at two cases of symptomatic COVID in vaccinated individuals

Researchers create a cell library to study how various sugars bind to and interact with receptors

Study offers clues to clinical diagnosis of nephronophthisis in adults

Study links muscle gene to type 2 diabetes

Researchers identify natural molecule that blocks the binding of human antibodies to SARS-CoV-2

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

Romantic relationships may play a role in mitigating the effects of trauma on student's drinking behavior

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

RNA secondary structures can contribute strongly to gene regulation, research shows

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Experts to present latest research on aging and longevity at the 8th Aging Research & Drug Discovery Meeting

Understanding the DNA Damage Response in Innate Immunity eBook

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Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo