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Nanostructures made of DNA pave way towards functional drug-delivery vehicles

New study shows that nanostructures constructed of DNA molecules can be programmed to function as pH-responsive cargo carriers, paving the way towards functional drug-delivery vehicles.

29 Apr 2019

Work stress and poor sleep associated with heart disease

A new study has reiterated the belief that work related stress and impaired sleep could be directly associated with raised blood pressure and risk of death due to heart disease.

28 Apr 2019

Regular endurance exercise leads to high Nrf2 nuclear translocation, DNA binding activity

Skeletal muscle mass and function becomes progressively compromised with aging, chronic disease, and physical inactivity.

26 Apr 2019

Stretchy wearable patch can do a health check while you work out

Next-generation fitness sensors could give deeper insights into human health through noninvasive testing of bodily fluids. A stretchy patch developed at KAUST could help this approach by making it easier to analyze sweat for critical biomarkers.

25 Apr 2019

Delving into tumor's cellular lineage may offer clues for customized therapies

To explain a person's actions in the present, it sometimes helps to understand their past, including where they come from and how they were raised.

25 Apr 2019

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.

25 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Exploring novel strategies to heal damage after a heart attack

For people who survive a heart attack, the days immediately following the event are critical for their longevity and long-term healing of the heart's tissue.

24 Apr 2019

Hole-forming protein could help control cancer growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become.

22 Apr 2019

Molecular target UNC45A is essential for cancer cell proliferation and tumor growth

Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. It is especially promising when this protein is dispensable for the growth of normal cells.

19 Apr 2019

Scientific breakthrough provides new hope for people living with multiple sclerosis

A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at Oregon Health & Science University have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord.

19 Apr 2019

Research sheds light on how leukemia cells become resistant to drugs

Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children's Hospital still haunt him more than a decade later.

17 Apr 2019

Keto diet - for the military, aging and epilepsy

Ketogenic diet or keto diet has been in the news as a trending diet option for weight watchers and those who wish to lose those extra pounds.

17 Apr 2019

Statins provide no benefit for 50 percent of patients, say researchers

Millions of patients do not benefit from taking statins and fail to achieve a cholesterol level low enough to reduce their risk of heart or stroke, report researchers.

16 Apr 2019

Ensuring 100% Accuracy in Antibody Protein Sequencing

The purpose of antibody protein sequencing is to accurately deduce every single amino acid present in the primary sequence. This is an issue with isoleucine and leucine which have the same molecular weight. Rapid Novor has developed a technique to determine these with 100% accuracy.

From Rapid Novor Inc 16 Apr 2019

Yeast strain provides manufacturing boost to low-calorie sweetener derived from lactose

The quest to satisfy the sweet tooth without adding to the waistline has a new weapon in its arsenal: a strain of yeast that can metabolize lactose, the sugar in dairy products, into tagatose, a natural sweetener with less than half the calories of table sugar.

16 Apr 2019

Initial gene analysis could result in more effective antipsychotic treatment

An initial gene analysis may yield better outcomes when patients are treated with the antipsychotic drugs risperidone and aripiprazole.

16 Apr 2019

Researchers identify cause of inherited metabolic disorder

A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder.

16 Apr 2019

Researchers discover how liver cells protect against viral attacks

Liver cells have an innate resistance to RNA viral infections like hepatitis A, dengue and Zika thanks to a protein called IRF1, according to researchers at the University of North Carolina at Chapel Hill and Tokyo Metropolitan Institute of Medical Science.

16 Apr 2019

CRISPR-scanning could lead to more effective treatments for cancer

11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors.

16 Apr 2019