Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

New medication may treat chemotherapy, radiotherapy-induced oral mucositis

Researchers from the University of Granada have developed new medication which could help to treat and prevent chemotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients.

30 Jun 2018

KU Cancer Center launches clinical trial to eliminate radiation therapy for HER2-positive breast cancer

Researchers at The University of Kansas Cancer Center have launched a clinical trial that eliminates radiation from the treatment protocol for an invasive type of breast cancer that accounts for one-fifth of all breast cancer patients.

30 Jun 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Atlantic Health System starts enrolling patients in four pancreatic cancer clinical trials

Atlantic Health System is now enrolling patients in four pancreatic cancer clinical trials. Angela Alistar, MD, a nationally known expert on pancreatic cancer, is serving as national Principal Investigator on the first trial and as local PI on three other trials.

30 Jun 2018

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

A DNA-level biomarker (MGMT promoter methylation) can be used to help predict survival outcomes in patients with high-risk, low-grade gliomas, according to a new study conducted through the NRG Oncology/RTOG collaborative clinical trials group and led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jun 2018

DNA methylation predicts survival outcome in patients with glioma

A new study has shown that survival rates among patients with glioma double if the tumor carries a methylated MGMT gene.

28 Jun 2018

Geriatric assessments could fine-tune cancer care for older adults

In a move to improve cancer care for older adults, the American Society of Clinical Oncology is recommending that all patients age 65 and older receive a geriatric assessment when considering or undergoing chemotherapy.

28 Jun 2018

Obese premenopausal women have decreased chance of developing breast cancer

Young women with high body fat have a decreased chance of developing breast cancer before menopause, according to scientists at the National Institutes of Health and their collaborators.

27 Jun 2018

New avenue for cancer treatment opens when one drug fails

A new class of cancer drugs – called CDK4/6 inhibitors -- recently approved to treat breast cancer can stunt the cancer's growth and replication.

27 Jun 2018

Polio virus could help brain cancer patients

According to researchers genetically altered poliovirus strains could help some patients of brain cancer. A team of researchers from Duke University in Durham, North Carolina, used modified polio virus strains in small groups of patients who had glioblastoma – a particularly deadly form of brain cancer. In these patients standard treatments have failed say the researchers and this novel therapy could help.

27 Jun 2018

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with recurrent glioblastoma, with a three-year survival rate of 21 percent in a phase 1 clinical trial.

26 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Men often tolerate stress urinary incontinence for more than two years before seeking medical help - and one-third put up with it for more than five years, making it important for doctors to check for this problem, a new study from UT Southwestern researchers advises.

25 Jun 2018

Higher BMI at younger age linked to reduced premenopausal breast cancer risk

Having a higher body mass index at a younger age is associated with a decreased risk of developing breast cancer before the menopause, major new research funded by Breast Cancer Now and other collaborators has found.

25 Jun 2018

ABPI associated with NHS for 70 years in pharmaceutical research

In this special year, both the NHS and the Association of the British Pharmaceutical Industry are celebrating our respective 70th anniversaries. The histories of these two organizations have been inextricably linked since 1948 and our relationship with the NHS continues to go from strength to strength.

25 Jun 2018

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Advanced Accelerator Applications S.A., a Novartis company and leader in nuclear medicine theragnostics, today announced that the first patients have been dosed in two Phase I/II clinical studies of radiolabeled PSMA-R2, a urea-based ligand of Prostate-Specific Membrane Antigen, which is commonly expressed on prostate cancer cells.

22 Jun 2018

Oncology News and Research

Further Reading

Streamlining and translating basic science discoveries into the clinic

New medication may treat chemotherapy, radiotherapy-induced oral mucositis

KU Cancer Center launches clinical trial to eliminate radiation therapy for HER2-positive breast cancer

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

Atlantic Health System starts enrolling patients in four pancreatic cancer clinical trials

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

DNA methylation predicts survival outcome in patients with glioma

Geriatric assessments could fine-tune cancer care for older adults

Obese premenopausal women have decreased chance of developing breast cancer

New avenue for cancer treatment opens when one drug fails

Polio virus could help brain cancer patients

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Researchers discover immune profile for effective cancer immunotherapy

New discovery suggests potential target for treating cancers and other diseases

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Study: Men tolerate stress urinary incontinence for years before seeking medical help

Higher BMI at younger age linked to reduced premenopausal breast cancer risk

ABPI associated with NHS for 70 years in pharmaceutical research

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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