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Birth defects more common if pregnant mothers smoke

New research has revealed that women who smoke during pregnancy are more likely to have a baby with a birth defect - smoking during pregnancy apparently doubles the risk of the baby having a cleft lip or palate.

5 Nov 2008

New weapon in the fight against obesity and diabetes

A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues.

4 Nov 2008

'Natural killer' immune cells reveal factors for reproductive success

Immune cells known as natural killer (NK) cells are linked with pregnancy problems including pre-eclampsia and recurrent miscarriage. Collaborative research between scientists at the Babraham Institute and Centre for Trophoblast Research in Cambridge is illuminating the role that pregnancy-related NK cells play in moderating the biochemical interactions at the boundary between maternal tissues and the developing foetus.

4 Nov 2008

Alzheimer's + diabetes + high blood pressure = a shorter life

A study has found that people with Alzheimer's disease who also suffer from diabetes and high blood pressure may die earlier.

4 Nov 2008

Beer is the beverage of choice for US Hispanics

Despite the considerable and growing numbers of Hispanics living in the United States, little is known about their alcohol-beverage preferences.

4 Nov 2008

Study looks at chronic medication use in children ages 5 to 19

America's tweens and teens more than doubled their use of type 2 diabetes medications between 2002 and 2005, with girls between 10 and 14 years of age showing a 166 percent increase.

4 Nov 2008

$Review of research into how cells and proteins repair fractured bones$

Review of research into how cells and proteins repair fractured bones

A review of research into how cells and proteins repair fractured bones published in the November 2008 issue of The Journal of the American Academy of Orthopaedic Surgeons demonstrates that understanding the biology behind this healing process may lead to improved and less invasive treatments for fractures.

4 Nov 2008

Targeting epigenetic changes helps tackle MLL-AF4 leukemias

A very difficult-to-treat child leukemia may benefit from the discovery of a small but potent epigenetic change that launches the cancer - but could potentially be reversed relatively easily, preventing cancer-promoting genes from being turned on.

4 Nov 2008

Study finds fears of HIV transmission in families with infected parent

Despite ongoing efforts to educate the public about HIV, a new study by researchers from UCLA, the RAND Corp., Harvard University and Children's Hospital Boston has found that two-thirds of families with an HIV-infected parent experience fears about spreading HIV in the home.

4 Nov 2008

Smaller mosquitoes more likely to be infected with viruses that cause diseases in humans

An entomologist at the Illinois Natural History Survey, a division of the new UI Institute for Natural Resource Sustainability, says smaller mosquitoes are more likely to be infected with viruses that cause diseases in humans.

4 Nov 2008

Rare immune cell may help those with Crohn's and colitis

The tonsils and lymphoid tissues in the intestinal tract that help protect the body from external pathogens are the home base of a rare immune cell newly identified by researchers at Washington University School of Medicine in St. Louis.

4 Nov 2008

Novel leukemia therapy shows promise for high-risk patients

Researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) are conducting clinical trials of a novel therapy aimed at revving up the immune system to combat a particularly difficult-to-treat form of leukemia.

4 Nov 2008

Symptoms of fibromyalgia related to dysfunction in parts of brain where pain is processed

Using single photon emission computed tomography (SPECT), researchers in France were able to detect functional abnormalities in certain regions in the brains of patients diagnosed with fibromyalgia, reinforcing the idea that symptoms of the disorder are related to a dysfunction in those parts of the brain where pain is processed.

4 Nov 2008

Diabetes and high blood pressure shorten lifespan in Alzheimer's disease

People with Alzheimer's disease who also have diabetes or high blood pressure may die sooner than people without such disorders, according to a study published in the November 4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2008

Bladder conditions - raising awareness

November is Bladder Health Month, and there's no better time to raise awareness of the bladder conditions that affect millions of patients, who often suffer in silence with common, treatable symptoms.

4 Nov 2008

New clinical study will help doctors assess abnormal bleeding

How do you know if you bleed normally? Scientists at The Rockefeller University Hospital's Center for Clinical and Translational Science (CCTS) aim to answer that question more definitively with the launch of an assessment tool designed to help physicians and researchers more accurately determine what is inside and outside the normal range of bleeding symptoms.

3 Nov 2008

Halozyme Therapeutics starts phase 2 trial of insulin with rHuPH20 in type 1 diabetes

Halozyme Therapeutics, Inc. today announced it has started a Phase 2 study of proprietary recombinant human hyaluronidase enzyme (rHuPH20) co-formulations with Humulin R (regular insulin human injection) and with Humalog (insulin lispro) in Type 1 diabetic patients.

3 Nov 2008

Anti-VEGF drugs for retinal diseases could have serious side effects

Scientists at Schepens Eye Research Institute have found that reducing the levels of vascular endothelial growth factor (VEGF), which is best known as a stimulator of new blood vessel growth, in adult mice causes the death of photoreceptors and Muller glia -- cells of the retina that are essential to visual function.

3 Nov 2008

Genentech submits application to FDA for Avastin in the most aggressive form of brain cancer

Genentech has announced that the company submitted a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for Avastin (bevacizumab) as a therapy for people with previously treated glioblastoma. If accepted by the FDA, the application would be considered for an accelerated approval that allows provisional approval of medicines for cancer or other life-threatening diseases based on preliminary evidence suggesting clinical benefit.

3 Nov 2008

Persistent bacterial infection exploits killing machinery of immune cells

A new study reveals an important and newly discovered pathway used by disease-causing bacteria to evade the host immune system and survive and grow within the very cells meant to destroy them. This discovery may lead to new treatments and vaccines for tuberculosis (TB) and certain other chronic bacterial and parasitic infections.

3 Nov 2008