Efficacy News and Research

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Evaluating comparative effectiveness of Pfizer-BioNtech and Moderna vaccines among US veterans

A new study provided evidence of a lower 24-week risk of COVID-19–related outcomes among recipients of the mRNA-1273 vaccine, compared to their counterparts who received the BNT162b2 vaccine.

3 Dec 2021

Effectiveness of COVID-19 vaccines in New York State

A new study reports that BNT162b2 booster doses are safe and have shown enhancement in short-term protection against the Delta variant.

3 Dec 2021

Quantum mechanical model offers insights into SARS-CoV-2 evolution

Researchers used an ab initio full quantum mechanical model to characterize the spike protein RBD interactions with host cells and gain mechanistic insights into SARS-CoV-2 evolution.

3 Dec 2021

Predicting COVID-19 transmission dynamics in the USA

Researchers used an SEIR type compartmental model to predict the dynamics of COVID-19 transmission in the USA.

3 Dec 2021

Subcutaneously administered monoclonal antibodies associated with reduced hospitalization and death amongst COVID 19 outpatients

A new preprint describes the results of a study that compares intravenous administration of one such therapy to its subcutaneous use, in terms of clinical outcomes.

3 Dec 2021

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Researchers from the USA discuss the development and validation of CRISPR-Cas12-based COVID-19 variant DETECTR® assay for the detection of SARS-CoV-2.

3 Dec 2021

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

A recent study reports neutralizing efficacy for a fused peptide-antibody molecule against SARS-CoV-2, providing hope that therapeutic neutralizing antibodies may soon be available.

3 Dec 2021

New genetic technology for gene expression analysis of cancer cells

In this interview, News-Medical speaks to Dr. Rong Lu about her recent research into the development of a new genetic technology for gene expression analysis of cancer cells.

3 Dec 2021

Study shows difference in outcomes for women treated with checkpoint inhibitors for melanoma

A class of cancer immunotherapy called checkpoint inhibitors has revolutionized cancer treatment. It's a new way to attack the disease by unleashing the immune system.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

A recent study describes the association between time elapsed since the second dose of the Pfizer-BioNTech BNT162b2 vaccine and risk of COVID-19.

1 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Fourth shot of Moderna COVID vaccine improves Delta variant neutralization in kidney transplant patients

New research suggests that a fourth dose of the mRNA-1273 vaccine in kidney transplant recipients improves Delta variant serum neutralization.

1 Dec 2021

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's disease.

1 Dec 2021

Safety and immunogenicity of different COVID-19 booster vaccines

New study findings suggest that booster vaccination with an mRNA-based vaccine has the highest immunogenicity against the COVID-19 Delta variant.

1 Dec 2021

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

A team of researchers from UK and US institutions created a large panel of mAbs derived from memory B cells of convalescent Beta subjects to better understand the antigenic landscape of Beta.

1 Dec 2021

Interventions for preventing COVID-19 outbreaks in military basic training

New research findings suggest that military basic training is a unique environment that necessitates the development of tailored solutions for minimizing COVID-19 outbreaks.

1 Dec 2021

Major life events may affect a person's physical activity levels and heart health

Starting a new school or a new job, having a baby or entering retirement are major life events that significantly affect a person's physical activity level, which may lead to poorer heart health.

1 Dec 2021

Study shows long-term safety and biologic activity of golodirsen in DMD patients

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics.

1 Dec 2021

Efficacy News and Research

Evaluating comparative effectiveness of Pfizer-BioNtech and Moderna vaccines among US veterans

Effectiveness of COVID-19 vaccines in New York State

Quantum mechanical model offers insights into SARS-CoV-2 evolution

Predicting COVID-19 transmission dynamics in the USA

Subcutaneously administered monoclonal antibodies associated with reduced hospitalization and death amongst COVID 19 outpatients

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

New genetic technology for gene expression analysis of cancer cells

Study shows difference in outcomes for women treated with checkpoint inhibitors for melanoma

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Fourth shot of Moderna COVID vaccine improves Delta variant neutralization in kidney transplant patients

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

Safety and immunogenicity of different COVID-19 booster vaccines

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

Interventions for preventing COVID-19 outbreaks in military basic training

Major life events may affect a person's physical activity levels and heart health

Study shows long-term safety and biologic activity of golodirsen in DMD patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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