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In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

Organ transplant patient dies after receiving Covid-infected lungs

Doctors say a woman in Michigan contracted covid-19 and died last fall two months after receiving a tainted double-lung transplant from a donor who turned out to harbor the virus that causes the disease — despite showing no signs of illness and initially testing negative.

22 Feb 2021

New diagnostic approach to evaluate the skin complications of diabetes mellitus

The multidisciplinary research team published their research "Skin complications of diabetes mellitus revealed by polarized hyperspectral imaging and machine learning" recently in the IEEE transactions on Medical imagining.

22 Feb 2021

'The Virtual Brain': A new tool for epilepsy surgery planning

Epilepsy is one of the most common neurological disorders, affecting over 50 Million people worldwide. Patients suffer from seizures caused by sudden neuronal activity engaging at times large networks of the brain.

20 Feb 2021

Minority women with less education and income have lower access to 3D mammography

Women of minority races and ethnicities and with less education and income have had relatively lower access to 3D mammography, a technology that can improve breast cancer detection and decrease false alarms, according to research published today.

20 Feb 2021

New isolated lymphatic vessel lumen perfusion system to evaluate nanoparticle dynamics

Nanoparticles used in drug delivery systems, bioimaging, and regenerative medicine migrate from tissues to lymphatic vessels after entering the body, so it is necessary to clarify the interaction between nanoparticles and lymphatic vessels.

20 Feb 2021

Low-frequency brain stimulation prevents seizures in mice with temporal lobe epilepsy

Epileptic activity originating from one or more diseased brain regions in the temporal lobe is difficult to contain.

20 Feb 2021

ESO guidelines provide recommendations on intravenous thrombolysis for acute ischemic stroke

Patients with stroke due to blood clots in brain arteries ('ischaemic stroke') can be treated with clot-dissolving drugs called 'thrombolytics'.

20 Feb 2021

Developing Biochemically Sensitive Membranes with Electrochemistry

In this interview, News-Medical Life Sciences talks to Lane Baker, Professor of Chemistry at Indiana University Bloomington about the role of electrochemistry in developing biochemically sensitive membranes as well the work ongoing at the Baker lab.

From Pittcon 19 Feb 2021

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.

19 Feb 2021

An optimized process to isolate and purify magnetic nanoparticles

Magnetic nanoparticles biosynthesized by bacteria might soon play an important role in biomedicine and biotechnology. Researchers of the University of Bayreuth have now developed and optimized a process for the isolation and purification of these particles from bacterial cells.

19 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell.

18 Feb 2021

Major project reduces inpatient falls, saves £13 million for UK’s National Health Service

A 10-year project to reduce the number of inpatient falls has saved the United Kingdom's National Health Service more than £13 million, thanks to a team of researchers including an academic from Kingston University, London and St George's, University of London.

18 Feb 2021

Researchers identify antibody that removes amyloid plaques without the risk of brain bleeds

As people age, a normal brain protein known as amyloid beta often starts to collect into harmful amyloid plaques in the brain. Such plaques can be the first step on the path to Alzheimer's dementia.

18 Feb 2021

Researchers measure baseline activity of single neurons

Our brains are complicated webs of billions of neurons, constantly transmitting information across synapses, and this communication underlies our every thought and movement.

18 Feb 2021

3D microscopy sheds light on the body’s immune response to obesity

Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood.

18 Feb 2021

Radiological images reveal how COVID virus can trigger the body to attack itself

Muscle soreness and achy joints are common symptoms among COVID-19 patients. But for some people, symptoms are more severe, long-lasting, and even bizarre, including rheumatoid arthritis flares, autoimmune myositis, or "COVID toes."

18 Feb 2021

New collaborative project to study the complex roles of lipids in health, disease

A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

17 Feb 2021

Imaging News and Research

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Study reveals mechanism for translation of maternally inherited mitochondrial genome

Organ transplant patient dies after receiving Covid-infected lungs

New diagnostic approach to evaluate the skin complications of diabetes mellitus

'The Virtual Brain': A new tool for epilepsy surgery planning

Minority women with less education and income have lower access to 3D mammography

New isolated lymphatic vessel lumen perfusion system to evaluate nanoparticle dynamics

Low-frequency brain stimulation prevents seizures in mice with temporal lobe epilepsy

ESO guidelines provide recommendations on intravenous thrombolysis for acute ischemic stroke

Developing Biochemically Sensitive Membranes with Electrochemistry

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions

An optimized process to isolate and purify magnetic nanoparticles

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Major project reduces inpatient falls, saves £13 million for UK’s National Health Service

Researchers identify antibody that removes amyloid plaques without the risk of brain bleeds

Researchers measure baseline activity of single neurons

3D microscopy sheds light on the body’s immune response to obesity

Radiological images reveal how COVID virus can trigger the body to attack itself

New collaborative project to study the complex roles of lipids in health, disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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