Immune System News and Research

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Insight into role of aging in response to SARS-CoV-2 infection

Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server medRxiv*.

3 Feb 2021

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.

3 Feb 2021

Scientists receive award to explore how diet and metabolism influence the immune system

A pair of scientists from Van Andel Institute and the National Institute of Allergy and Infectious Diseases have been granted a three-year, $1.5 million Allen Distinguished Investigator award from The Paul G. Allen Frontiers Group, a division of the Allen Institute, to better understand how diet and metabolism influence the immune system's ability to fight off threats such as infections.

3 Feb 2021

Moffitt researchers reveal why some ovarian cancer patients evolve better than others

The prognosis of ovarian cancer is poor, with an estimated five-year survival of only 40% for advanced disease, the stage at which most ovarian carcinomas are diagnosed.

3 Feb 2021

Tiny molecular motions are of key significance in modern anti-cancer drugs

Modern immunotherapeutic anti-cancer drugs support a natural mechanism of the immune system to inhibit the growth of cancer cells.

3 Feb 2021

People with severe mental disorders have higher risk of death from COVID-19

People with severe mental disorders have a significantly increased risk of dying from COVID-19. This has been shown in a new study from Umeå University and Karolinska Institutet in Sweden.

3 Feb 2021

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

A new preprint examines Long COVID-19, aiming to identify the underlying immunologic status in such patients.

3 Feb 2021

Childhood diet can alter the gut microbiome for life

Eating too much fat and sugar as a child can alter your microbiome for life, even if you later learn to eat healthier, a new study in mice suggests.

3 Feb 2021

Study examines motivations and barriers to convalescent plasma donation in the UK

Researchers have given new insights into why people would choose to donate Covid-19 plasma after recovering from the virus, which will be used to support the recruitment of convalescent plasma donors to help treat current Covid-19 patients and support ongoing trials.

3 Feb 2021

New genome editing technology could pave way for non-viral delivery systems

Researchers from Peter the Great St.Petersburg Polytechnic University (SPbPU) in collaboration with colleagues from Belgium take a step in the development of genome editing technology.

3 Feb 2021

Advances in tumor models could expand effectiveness of cancer immunotherapy

Scientists are hoping advances in cancer research could lead to a day when a patient's own immune system could be used to fight and destroy a wide range of tumors.

3 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Immune System News and Research

Insight into role of aging in response to SARS-CoV-2 infection

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

Scientists receive award to explore how diet and metabolism influence the immune system

Moffitt researchers reveal why some ovarian cancer patients evolve better than others

Tiny molecular motions are of key significance in modern anti-cancer drugs

People with severe mental disorders have higher risk of death from COVID-19

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

Childhood diet can alter the gut microbiome for life

Study examines motivations and barriers to convalescent plasma donation in the UK

New genome editing technology could pave way for non-viral delivery systems

Advances in tumor models could expand effectiveness of cancer immunotherapy

New process separates beneficial glucocorticoids from unwanted side-effects

Two-dose regimen of adenovirus-based vaccine offers 91.6% efficacy against COVID-19

Lysosomal-immune axis associated with COVID-19 severity

Remyelinating drug shows potential to improve vision in patients with MS

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Breast cancer‐on‐a‐chip to test the effectiveness of checkpoint inhibitor drugs

Yale scientists develop an injection-based therapy for skin cancer

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