Adenocarcinoma News and Research

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Adenocarcinoma is cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties.

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

A group of the nation's premier cancer researchers led by the Baylor Scott & White Research Institute and the Translational Genomics Research Institute -- has secured a $5.13 million federal grant to develop an early detection system for pancreatic cancer, the nation's third-leading cause of cancer-related death.

11 Dec 2017

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

FDA grants approval to first biosimilar for treatment of patients with breast, stomach cancers

The U.S. Food and Drug Administration today approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+).

4 Dec 2017

Researchers identify oral bacteria linked to esophageal cancer

Researchers at NYU Langone Health's Perlmutter Cancer Center report that at least three kinds of bacteria in the mouths of Americans may heighten or lower their risk of developing esophageal cancer.

1 Dec 2017

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

An analysis of bacteria present in the mouth showed that some types of bacteria that lead to periodontal disease were associated with higher risk of esophageal cancer.

1 Dec 2017

Researchers develop new tool to share clinico-genomic data

Researchers from Universidad Politécnica de Madrid have developed a new tool that provides standard and shared clinico-genomic data among European healthcare institutions.

20 Nov 2017

Study confirms safety and efficacy of new second line treatment for metastatic colorectal cancer

A randomized trial in 650 patients has confirmed the safety and efficacy of a new second line treatment for metastatic colorectal cancer, researchers report at the ESMO Asia 2017 Congress.

20 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Four main genes linked to survival of pancreatic cancer patients

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in JAMA Oncology.

3 Nov 2017

Cancer researchers make breakthrough in identifying genetic changes during immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That's particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which initially was effective against their tumors.

28 Oct 2017

RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S.

11 Oct 2017

New studies provide insight into treatments for Barrett's esophagus

The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).

6 Oct 2017

Cancers linked to obesity account for 40% of all cancers in the US, report states

Being obese or overweight is linked to an increased risk of developing 13 types of cancer, according to the latest Vital Signs report from the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute. These cancers accounted for approximately 40% of all cancers diagnosed in the US, in 2014.

4 Oct 2017

Experts call for greater focus on effective screening methods to help save lives from digestive cancers

Experts from United European Gastroenterology (UEG), presenting at the European Digestive Cancer Days Conference in Prague today, are calling on European governments to focus their efforts on developing early diagnosis techniques, in order to save thousands of lives from digestive cancers including a more targeted approach to ensure at risk patients don’t ‘slip through the early-detection net’.

28 Sep 2017

New trial confirms superiority of triplet regimen over standard care in resectable esophago-gastric cancer

The superiority of docetaxel based triplet therapy over standard care in patients with resectable oesophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Female patients with esophageal cancer have superior response to treatment, study reveals

Female patients with locally advanced esophageal cancer that is treated with chemotherapy and radiation therapy before surgery are more likely to have a favorable response to the treatment than male patients are, and women are less likely to experience cancer recurrence, according to a study published online today in The Annals of Thoracic Surgery.

22 Aug 2017

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research.

17 Aug 2017

Study reveals strong prognostic indicators of survival in resected pancreatic cancer

A new study of patients who underwent curative surgical removal of a pancreatic ductal adenocarcinoma showed that two of the nine preoperative factors analyzed were strongly predictive of poor prognosis regardless of the tumor stage.

10 Aug 2017