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Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Researchers compared the immunogenicity of the reduced and standard doses of the BNT162b2 and mRNA-1273 vaccine in adults immunized with two doses of the CoronaVac vaccine.

8 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

An new study reports that a third dose of the Pfizer BNT162b2 vaccine produces high levels of anti-spike IgG antibodies in kidney transplant recipients.

6 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

Longitudinal analysis of CD4+ T cells and antibody responses to common cold coronaviruses

Scientists have recently revealed that memory T cell responses to common cold coronaviruses stably persist for a long time.

4 Mar 2022

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

In a new study, researchers presented the Multiscale potential of heat-diffusion for affinity-based trajectory embedding approach that identified multimodal signatures of SARS-CoV-2shut.

3 Mar 2022

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

In a new study, researchers evaluated the immune responses induced by the mRNA-based SARS-CoV-2 vaccination against SARS-CoV-2 variants in multiple myeloma patients.

1 Mar 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers - and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and disease states.

24 Feb 2022

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Every kind of T cell has a job to do. A healthy immune system makes sure no T cell oversteps.

22 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Emergence of new HIV variant underscores importance of monitoring virus mutations

A new study published in the journal Science reported the presence of a subtype-B variant of HIV-1 with remarkably high virulence, circulating in the Netherlands during the past two decades.

20 Feb 2022

New finding may aid in development of vaccines against future animal-to-human viral diseases

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans - including SARS-CoV-2, the cause of COVID-19 - may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

Study shows link between oral microbiome and naturally occurring alveolar bone loss

It is becoming increasingly clear that the human microbiome – the collection of bacteria, viruses and fungi that live on and within us – significantly contributes to our health.

17 Feb 2022

CD4 News and Research

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Current progress in SARS-CoV-2 vaccine candidates

Combating COVID cytokine storm with targeted nucleic acid therapies

CD4 T-cell immunity active six months into COVID-19 convalescence

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Longitudinal analysis of CD4+ T cells and antibody responses to common cold coronaviruses

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

Study compares heterologous and homologous third vaccination in kidney transplant recipients

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

LJI researchers discover new genes in CD4+ "helper" T cell subsets

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Mouse-adapted virus model to study persistent COVID induced lung disease

Emergence of new HIV variant underscores importance of monitoring virus mutations

New finding may aid in development of vaccines against future animal-to-human viral diseases

Study shows link between oral microbiome and naturally occurring alveolar bone loss

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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