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NIH funding supports innovative lupus research using DNA mimic molecules

Lupus causes chronic pain, fatigue, and potentially organ damage for 1.5 million Americans and is a challenge for researchers trying to find better treatments.

12 Dec 2024

PATINA trial demonstrates benefit of palbociclib in HR+ HER2+ metastatic breast cancer

Alliance Foundation Trials, LLC (AFT) and Pfizer Inc. today announced results from the phase III PATINA trial demonstrating that the addition of palbociclib (IBRANCE) to current standard-of-care first-line maintenance therapy (following induction chemotherapy) resulted in statistically significant and clinically meaningful improvement in progression-free survival (PFS) by investigator assessment in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (MBC).

12 Dec 2024

Higher cardiorespiratory fitness improves cognitive function in older age

Higher cardiorespiratory fitness in older age is linked to the preservation of several core aspects of cognitive ability that are vulnerable to age-related decline, finds research published online in the British Journal of Sports Medicine.

11 Dec 2024

Post-COVID health risks: Obesity fuels sequelae, smoking hits memory

Obesity significantly increases the risk of post-COVID-19 long-term sequelae, while smoking is primarily linked to memory disorders but does not raise the risk of long COVID symptoms or hospitalization.

9 Dec 2024

California official comes out of retirement to lead troubled mental health commission

Veteran California public servant Will Lightbourne has stepped in as interim executive director of the state's mental health commission after its previous executive director resigned following conflict of interest allegations.

9 Dec 2024

Long-COVID lingers in children

A 24-month study reveals that 7.2% of children consistently experience long-COVID symptoms, with tiredness, sleep issues, and headaches most commonly reported, highlighting the need for targeted interventions.

5 Dec 2024

Does air pollution worsen Long COVID? Researchers weigh in

Exposure to air pollutants, particularly particulate matter, may increase Long COVID risk by worsening initial infection severity, but noise, light, and green spaces show no significant impact, a Catalonian study reveals.

5 Dec 2024

Chikungunya's health and economic impact likely underestimated

This study assesses chikungunya's health and economic impacts, revealing significant burdens on health systems and a global cost of approximately $49.9 billion.

5 Dec 2024

Women with infertility have higher risk of developing systemic autoimmune diseases

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

4 Dec 2024

Advanced modeling unveils hidden costs of global chikungunya infection

The health and financial implications of the emerging threat of mosquito-borne chikungunya viral infection have most likely been significantly underestimated, with total costs probably approaching US$ 50 billion in 2011-20 alone, suggests a comprehensive data analysis, published in the open access journal BMJ Global Health.

4 Dec 2024

Study finds T cell exhaustion in chronic fatigue syndrome patients

Chronic fatigue syndrome creates conditions where pathogen-killing immune T cells become exhausted, according to a new Cornell University study.

3 Dec 2024

CBT and rehabilitation show modest benefits for long COVID recovery, study finds

CBT and combined rehabilitation offer moderate benefits for long COVID, enhancing quality of life and reducing fatigue, but evidence quality is variable.

3 Dec 2024

Understanding the role of sleep in dementia and associated illnesses

A new review was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21, titled, "Sleep deprivation in dementia comorbidities: focus on cardiovascular disease, diabetes, anxiety/depression and thyroid disorders."

2 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024