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Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.

30 Oct 2025

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a major contributor to heart disease.

30 Oct 2025

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

29 Oct 2025

MAGIC: A powerful tool to understand the origin of cancer

The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled.

29 Oct 2025

Researchers discover a previously unknown genetic cause for microcephaly

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.

28 Oct 2025

E. coli in retail meat linked to thousands of urinary infections

Research reveals a significant link between E. coli in meat and urinary tract infections, particularly in vulnerable communities in Southern California.

28 Oct 2025

New software enables real-time pathogen surveillance in the air and environment

Metagenomics is the study of all organisms present in a particular environment, such as soil, water, or the human body. A key part of metagenomic analysis is understanding what species are present (classification), how much of each there is (abundance), and the function of the microorganisms present.

28 Oct 2025

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria

27 Oct 2025

Obesity’s health risks shift with age and sex, new genetic study reveals

Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.

27 Oct 2025

Ancient DNA uncovers paratyphoid and relapsing fever among Napoleonic troops

Scientists from the Institut Pasteur have genetically analyzed the remains of former soldiers who retreated from Russia in 1812.

24 Oct 2025

Unveiling the dual role of HIV integrase in viral replication

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

24 Oct 2025

Study reveals impact of viral combinations on infant respiratory illness severity

A new study led by researchers at National Jewish Health has revealed that, while a wide range of viruses can cause lower respiratory tract illnesses (LRIs) in infants, certain viruses and viral combinations dramatically increase the risk of severe disease.

24 Oct 2025

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., Director of the Movement Disorders Program at Boston Children's, and his team will lead this multi-center effort.

24 Oct 2025

Researchers trace the ancient origins of an urban mosquito species

New research has uncovered the ancient origins of an urban mosquito species, Culex pipiens form molestus, also known as the 'London Underground mosquito' – disproving a long-held theory of when it first evolved.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

New gene-editing method can correct many disease-causing mutations in mammalian cells

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

23 Oct 2025

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary human T cells, addressing a key manufacturing and scalability challenge in next-generation cell therapies.

21 Oct 2025

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist therapy.

21 Oct 2025

Molecular evidence connects higher childhood cognitive function to longer lifespan

Researchers led by Dr. W. David Hill at the University of Edinburgh have identified a significant genetic correlation between childhood cognitive function and longevity, providing the first molecular genetic evidence that intelligence measured in youth shares genetic factors with lifespan.

21 Oct 2025

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.

19 Oct 2025

Genome News and Research

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

MAGIC: A powerful tool to understand the origin of cancer

Researchers discover a previously unknown genetic cause for microcephaly

E. coli in retail meat linked to thousands of urinary infections

New software enables real-time pathogen surveillance in the air and environment

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Obesity’s health risks shift with age and sex, new genetic study reveals

Ancient DNA uncovers paratyphoid and relapsing fever among Napoleonic troops

Unveiling the dual role of HIV integrase in viral replication

Study reveals impact of viral combinations on infant respiratory illness severity

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Researchers trace the ancient origins of an urban mosquito species

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

New gene-editing method can correct many disease-causing mutations in mammalian cells

Epigenetic editing enables safer and more effective T cell therapies

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Molecular evidence connects higher childhood cognitive function to longer lifespan

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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