Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Ozone exposure may contribute to reduced oxygen levels and arterial stiffness

Ozone (O3) exposure may reduce the availability of oxygen in the body, resulting in arterial stiffening due to the body's natural response to create more red blood cells and hemoglobin, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

22 Jan 2025

Surgery reduces accident risk in sleep apnea patients

Sleepiness at the wheel is a significant contributing factor to motor vehicle accidents. A new analysis published in Otolaryngology–Head and Neck Surgery reveals that for people with sleep apnea, getting surgery for their condition may lessen their risk of such accidents compared with using a Continuous Positive Airway Pressure (CPAP) device at night or receiving no treatment.

22 Jan 2025

Muscle fat infiltration predicts heart disease risk better than BMI, study finds

Skeletal muscle fat infiltration (IMAT) is linked to coronary microvascular dysfunction and increased cardiovascular risk, independent of BMI and traditional risk factors.

21 Jan 2025

Space research offers new hope for heart cell therapy

A team of researchers led by Emory's Chunhui Xu recently found that heart muscle cells can grow -and survive in the microgravity environment of space.

21 Jan 2025

TyG index linked to obesity measures can predict hypertension risk in US adults

A study found that the triglyceride-glucose (TyG) index, combined with obesity measures, significantly correlates with hypertension risk in American adults, offering potential for improved cardiovascular risk assessment.

20 Jan 2025

Intermuscular fat increases risk of heart disease independent of BMI

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal today (Monday).

20 Jan 2025

Key biomarkers linked to obesity-induced heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Many studies have reported that obesity causes heart failure (HF) pathogenesis.

17 Jan 2025

Researchers investigate myocarditis in preschoolers caused by parvovirus B19 outbreak

Researchers document the harmful consequences of myocarditis in preschool students, caused by a regional outbreak of parvovirus B19 in northern Greece.

17 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

Global Commission proposes new framework for obesity diagnosis and treatment

A global Commission, published in The Lancet Diabetes & Endocrinology and endorsed by 75 medical organizations around the world, presents a novel, nuanced approach to diagnose obesity, based on other measures of excess body fat in addition to body mass index (BMI), and objective signs and symptoms of ill health at the individual level.

15 Jan 2025

The role of inflammation in the pathogenesis of heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular disease remains a leading cause of death and disability worldwide. Heart failure (HF) is the end stage of various cardiovascular diseases. Despite recent advancements in understanding of HF pathogenesis and treatment, the prognosis of patients with HF remains poor.

15 Jan 2025

New model analyzes CT scans to identify high-risk individuals

Researchers at Case Western Reserve University, University Hospitals and Houston Methodist will harness the power of artificial intelligence (AI) to more accurately predict risk of heart failure and other cardiovascular events, including estimating when an adverse event might occur, by developing an AI model that "learns" from patient scans.

15 Jan 2025

Developing and refining muscle atrophy models for drug discovery

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have widely used various animal and cellular models to gain a deeper understanding of the pathophysiological mechanisms of muscle atrophy and develop effective treatment strategies.

9 Jan 2025

Research from second pig heart transplant provides new directions for xenotransplantation

Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.

9 Jan 2025

Parvovirus B19 myocarditis cases reported in preschoolers from Northern Greece

Myocarditis is a rare yet serious condition known for the inflammation of the heart muscle, also known as the myocardium. In severe cases of myocarditis, the heart muscle becomes extremely weak and fails to pump blood effectively.

9 Jan 2025

Mutation in ASXL1 gene triggers chain reaction leading to blood disorders

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of events during blood cell production.

8 Jan 2025

Trametinib shows promise in treating severe hypertrophic cardiomyopathy in children

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published today in JACC: Basic to Translational Science.

8 Jan 2025

Heart attack recovery enhanced by human stem cell spheroids, study shows

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that overexpress cyclin D2 and are knocked out for human leukocyte antigen classes I and II.

7 Jan 2025

Are individuals with advanced breast cancer more likely to have cardiovascular disease?

Research shows that patients with advanced breast cancer have higher odds of cardiovascular disease, emphasizing the importance of personalized screening.

7 Jan 2025

Metastatic breast cancer associated with higher risk of pre-existing cardiovascular disease

Cardiovascular disease (CVD) and cancer are the two leading causes of death in the U.S. According to researchers from The University of Texas MD Anderson Cancer Center, patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis CVD compared to those with early-stage cancer at diagnosis.

2 Jan 2025