Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Studying coagulopathy in COVID-19

A new study published in the journal Diagnostics provided an overview of ROTEM with a particular focus on interpreting the symmetrical clot formation curve. Researchers also introduced new parameters that could aid in distinguishing between COVID-19 patients and outcomes.

28 Feb 2022

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development.

24 Feb 2022

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

A new drug, administered in combination with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer, according to a trial published in The New England Journal of Medicine.

23 Feb 2022

Study offers a new, effective therapeutic option against glioblastoma

A study recently accepted for publication in The Journal of Clinical Investigation describes a new and effective therapy to treat glioblastoma: the concomitant use of ADI-PEG20 together with focal brain radiotherapy.

22 Feb 2022

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored by bluebird bio.

16 Feb 2022

Pandemic has led to delay in diagnosis of breast cancer

The COVID-19 pandemic upended many aspects of daily life, particularly in the first months and year. Not least among the changes: decreased use of ordinary health care, such as routine medical exams and screenings.

15 Feb 2022

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

MUSC Hollings Cancer Center researcher Sophie Paczesny, M.D., Ph.D., recently received a four-year grant from the National Heart, Lung, and Blood Institute to investigate solutions to help doctors to fight complications after pediatric bone marrow transplantation (BMT).

12 Feb 2022

Molecular treatment works against metastatic cancer that spread to the brain

Mount Sinai researchers conducting clinical trials of a drug targeting a cancer gene found that it increased metastatic cancer patients' survival and was able to work within the brain, according to a study published in Clinical Cancer Research in February.

10 Feb 2022

New personalized test to detect leukemia relapse sooner and avoid false negative results

Researchers have developed a new protocol for monitoring acute lymphoblastic leukemia (ALL), the most common cancer in children, to inform more effective treatment strategies and detect disease recurrence.

7 Feb 2022

Gene therapy may be a curative treatment option for patients with transfusion-dependent beta-thalassemia

A novel gene therapy promoted transfusion independence in more than 90 percent of adult and pediatric patients with transfusion-dependent beta-thalassemia, according to a recent clinical trial published in The New England Journal of Medicine.

3 Feb 2022

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Researchers at University Hospitals Seidman Cancer Center and Case Western Reserve University have developed a novel approach to chimeric antigen receptor (CAR) T-cell therapy for B-cell cancers that triples the targeted antigens on cancer cells – a "back up" approach that promises to greatly reduce the potential for antigen escape currently found in CAR T therapies that solely target CD19.

2 Feb 2022

Study provides a new treatment option for patients with relapsed B-cell lymphoma

A new therapy showed improvement over the standard treatment for relapsed B-cell lymphoma, according to a study published in the New England Journal of Medicine.

26 Jan 2022

Exploring hematological alterations in COVID-19 patients

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality.

26 Jan 2022

Trastuzumab combined with trimodality treatment for HER2-overexpressing esophageal cancer found to be ineffective

The NRG Oncology clinical trial NRG-RTOG 1010, studying the addition of the drug trastuzumab to chemoradiation and surgery, did not reach its primary goal of improving disease-free survival (DFS) rates for patients with HER2 overexpressing esophageal adenocarcinoma.

22 Jan 2022

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

Preliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability and feasibility of chimeric antigen receptor macrophage (CAR-M) has helped to establish the viability of this innovative immunotherapy, which advances the trailblazing scientific discovery of CAR T cell therapy- also pioneered at Penn- for solid cancer tumors and offers a promising new strategy in the fight against cancer.

11 Jan 2022

World renowned medical oncologist joins Henry Ford Cancer Institute

Internationally renowned medical oncologist Philip A. Philip, M.D., Ph.D., has joined Henry Ford Cancer Institute as director of Gastrointestinal Oncology and Neuroendocrine Oncology, medical director of Research and Clinical Care Integration, and co-leader of the Henry Ford Pancreatic Cancer Center.

6 Jan 2022

Siemens Healthineers Announces FDA Emergency Use Authorization for CLINITEST® Rapid COVID-19 Antigen Self-Test

The CLINITEST Rapid COVID-19 Antigen Self-Test has received FDA EUA for unsupervised self-testing for the SARS-CoV-2 virus by individuals age 14 and older (or adult-collected samples from individuals ages 2-13).

From Siemens Healthineers 4 Jan 2022

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

3 Jan 2022

Do reactive oxygen species play a role in fighting COVID-19?

Serum-free thiols are known to reflect the activity of reactive oxygen species in the body, and researchers have been examining the difference in these thiols in COVID-19 patients.

21 Dec 2021

Scientists develop new immunotherapy for cancer based on transplant rejection mechanism

A team of scientists at the University of Oslo, Oslo University Hospital Radiumhospitalet and Karolinska Institutet, led by Professor Johanna Olweus, has developed a new type of immunotherapy for cancer.

18 Dec 2021

Hematology News and Research

Further Reading

Studying coagulopathy in COVID-19

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

Study offers a new, effective therapeutic option against glioblastoma

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Pandemic has led to delay in diagnosis of breast cancer

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

Molecular treatment works against metastatic cancer that spread to the brain

New personalized test to detect leukemia relapse sooner and avoid false negative results

Gene therapy may be a curative treatment option for patients with transfusion-dependent beta-thalassemia

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Study provides a new treatment option for patients with relapsed B-cell lymphoma

Exploring hematological alterations in COVID-19 patients

Trastuzumab combined with trimodality treatment for HER2-overexpressing esophageal cancer found to be ineffective

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

World renowned medical oncologist joins Henry Ford Cancer Institute

Siemens Healthineers Announces FDA Emergency Use Authorization for CLINITEST® Rapid COVID-19 Antigen Self-Test

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Do reactive oxygen species play a role in fighting COVID-19?

Scientists develop new immunotherapy for cancer based on transplant rejection mechanism

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

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