Metabolic Disorders News and Research

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Study sheds light on how a group of novel organelle-based disorders affects cells

A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells.

10 Apr 2020

First genome sequences of SARS-CoV-2 viruses in Austria openly available

The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna.

3 Apr 2020

COVID-19 adversely impacts patients with cardiovascular disease and metabolic disorders

COVID-19 has a significant impact on patients with pre-existing conditions, many of which fall under the cardiovascular and metabolic disorder category.

3 Apr 2020

Diet affects sperm and the health of offspring

A new study published in the journal Molecular Cell, in March 2020, reports that parental diet is a crucial factor in the future metabolic health of the offspring.

19 Mar 2020

Dietary sugar has negative impact on health independent of obesity

Sugar-rich diets have a negative impact on health independent of obesity reports a new study led by the MRC London Institute of Medical Sciences, UK.

19 Mar 2020

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

Scientists identify genes involved in the development of diabetic kidney disease

By analyzing samples from hundreds of Finns with diabetes, scientists have identified genes, and the proteins they encode, that could be involved in the development of diabetic kidney disease.

12 Mar 2020

Reduced stress associated with changes in plasma metabolite profile

Reduced stress is linked to changes in the profile of plasma metabolites, a new study from the University of Eastern Finland shows.

25 Feb 2020

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

All life is challenged by oxidants -- reactive molecules or compounds that remove electrons from other molecules -- often with adverse effect, commonly referred to as oxidative stress.

25 Feb 2020

A step towards precision medicine for the management of monogenic diabetes

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycemia as a common feature. Of all its forms, monogenic diabetes - due to a mutation in one of the genes involved in the management of blood sugar levels - affects 1% to 4% of all cases of diabetes.

22 Feb 2020

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

Oncology was the top therapy area for non-industry sponsored clinical trials in 2019, making up 25.7% of all clinical trials.

21 Feb 2020

Cancer-fighting compound reduces fat in obese mice

Eric Prossnitz, PhD, and his team hope to help 93 million obese Americans fight their fat.

6 Feb 2020

Shift workers at increased risk for sleep disorders and metabolic syndrome

Shift workers are at a significantly increased risk for sleep disorders and metabolic syndrome, which increases a person's risk for heart disease, stroke and type 2 diabetes mellitus.

3 Feb 2020

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

A team of researchers in the University of Tennessee Health Science Center's College of Medicine has been awarded a $1.98 million grant from the National Institute of Diabetes and Digestive and Kidney Disease, a division of the National Institutes of Health, for a novel approach to studying diabetes.

3 Feb 2020

Long noncoding RNA can protect our metabolism against metabolic complications

Unlike what we commonly refer to as 'genes', these phantom genes or 'Long noncoding RNA' (LncRNAs) do not lead to the production of proteins that our cells, and thus our entire bodies are made of.

31 Jan 2020

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

24 Jan 2020

Children born to mothers with gestational diabetes and preeclampsia at risk for higher BMI

Childhood obesity is a growing problem in the United States. For children, obesity is defined as having a body mass index at or above the 95th percentile, and according to the Centers for Disease Control and Prevention, 18.5% of children between the ages of 2 and 19 meet this criteria.

22 Jan 2020

Genes determining the browning of white fat finds study

The fat cells of the body play an essential role in the storage of energy and its release when necessary. Research has shown that apart from energy storage, these adipocytes or fat cells also play a role in hormonal balance and metabolism-regulating hunger. A new study titled, “Systems-genetics-based inference of a core regulatory network underlying white fat browning”, was published in the latest issue of the journal Cell Report.

13 Jan 2020

Researchers discover genes that could explain the Browning ability of white fat

Our fat cells, technically referred to as adipocytes, play an essential role in regulating energy balance in our body.

9 Jan 2020

Caffeine may offset some negative health effects of obesogenic diet

A new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides.

19 Dec 2019

Metabolic Disorders News and Research

Study sheds light on how a group of novel organelle-based disorders affects cells

First genome sequences of SARS-CoV-2 viruses in Austria openly available

COVID-19 adversely impacts patients with cardiovascular disease and metabolic disorders

Diet affects sperm and the health of offspring

Dietary sugar has negative impact on health independent of obesity

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

Scientists identify genes involved in the development of diabetic kidney disease

Reduced stress associated with changes in plasma metabolite profile

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

A step towards precision medicine for the management of monogenic diabetes

GlobalData: Oncology is top therapy area for non-industry-sponsored clinical trials

Cancer-fighting compound reduces fat in obese mice

Shift workers at increased risk for sleep disorders and metabolic syndrome

UTHSC researchers receive $1.98 million grant for novel approach to studying diabetes

Long noncoding RNA can protect our metabolism against metabolic complications

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

Children born to mothers with gestational diabetes and preeclampsia at risk for higher BMI

Genes determining the browning of white fat finds study

Researchers discover genes that could explain the Browning ability of white fat

Caffeine may offset some negative health effects of obesogenic diet

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