Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Brain and muscle cells found within kidney organoids

Researchers have discovered the presence of rogue brain and muscle cells inside kidney organoids and used artificial intelligence to remove them.

15 Nov 2018

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

An interview with Dr. Kevin Costa, discussing the miniaturized heart-in-a-jar model developed by Novoheart, and its applications in personalized medicine.

12 Nov 2018

Multidisciplinaryresearch teams selected to study age-related brain disorders

Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer's disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia?

12 Nov 2018

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment to investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline and uncover new therapies.

12 Nov 2018

Scientists identify 'skeleton key' for congenital kidney disease research

Scientists in Japan have found a 'skeleton key' for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease.

31 Oct 2018

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

A new gold standard for electrical measurement in the emerging in vitro world of three dimensional models. That's what Swiss medtech 3Brain has established by partnering with CSEM.

30 Oct 2018

Lab-created mini retinas allow researchers to understand retinal ganglion cell development

IUPUI biologists are growing 'mini retinas' in the lab from stem cells to mimic the growth of the human retina. The researchers hope to use the research to restore sight when critical connections between the eye and the brain are damaged.

25 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Study to explore bioethics of brain organoids

Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids.

16 Oct 2018

Lab grown retinal cells provide clues to color blindness treatment

Researchers have grown human retinal cells in the laboratories and thus attempted to understand the basis of color vision and its development in humans. The results showed that certain hormones are essential for the development of color vision in humans and were published in the latest issue of the journal Science.

11 Oct 2018

Researchers develop organoid that functions as real salivary gland

Researchers have successfully used induced pluripotent stem cells to grow a 3D salivary gland tissue that produces saliva when implanted in mice.

11 Oct 2018

Scientists succeed in growing functional salivary gland

A research group led by scientists from Showa University and the RIKEN Center for Biosystems Dynamics Research in Japan have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

11 Oct 2018

Researchers aim to create more authentic organoids for drug testing, transplantation

Human embryos start as a tiny mass of cells that are all the same. The first step in growing from a homogenous ball of cells into a complex individual with distinct organs and tissues is for the cells to divide into distinct populations.

10 Oct 2018

Researchers for the first time differentiate human inner ear cells in laboratory

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin.

3 Oct 2018

Engineering organoids from stem cells to model retina diseases

Gray Camp joined the Institute of Molecular and Clinical Ophthalmology Basel as Group Leader in Single Cell Genomics. His group will combine single-cell genomic tools and retina and cerebral "organoids" to explore the development of the human visual system.

28 Sep 2018

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Approximately 1.25 million Americans are living with type 1 diabetes, with an additional 40,000 people newly diagnosed every year.

27 Sep 2018

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective.

20 Sep 2018

UK and European research collaborations receive vote of confidence by three major cancer charities

UK and European research collaborations in cancer research have received a vote of confidence by three major cancer charities, with an announcement today of approximately £30 million into six international projects.

20 Sep 2018

Researchers grow stem cell-derived lung organoids that model human lung development

Researchers have now grown lung organoids from human embryonic stem cells that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs.

11 Sep 2018

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

Olympus Corporation today announced the U.S.-only launch of a new 3D cell analysis technology with ability to accurately analyze 3D cell cultures down to the nuclei, improving the reliability and accuracy of the entire drug discovery process, from compound selection to animal experimentation and clinical trials in humans.

From Evident Corporation - Life Sciences 11 Sep 2018

Organoids News and Research

Further Reading

Brain and muscle cells found within kidney organoids

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

Multidisciplinaryresearch teams selected to study age-related brain disorders

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

Scientists identify 'skeleton key' for congenital kidney disease research

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

Lab-created mini retinas allow researchers to understand retinal ganglion cell development

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Study to explore bioethics of brain organoids

Lab grown retinal cells provide clues to color blindness treatment

Researchers develop organoid that functions as real salivary gland

Scientists succeed in growing functional salivary gland

Researchers aim to create more authentic organoids for drug testing, transplantation

Researchers for the first time differentiate human inner ear cells in laboratory

Engineering organoids from stem cells to model retina diseases

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

UK and European research collaborations receive vote of confidence by three major cancer charities

Researchers grow stem cell-derived lung organoids that model human lung development

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

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