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New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Editorial emphasizes the critical role of heart-lung interactions in pulmonary vascular disease

A new editorial published in Comprehensive Physiology underscores the critical importance of understanding heart-lung interactions in pulmonary vascular disease (PVD).

4 Aug 2025

Creatine in your diet may benefit your digestive system

Findings suggest dietary creatine from meat may alleviate chronic constipation, with stronger effects observed in men and those without certain health issues.

4 Aug 2025

New research unveils vast influence of B vitamins on health and disease

Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from Tufts University and elsewhere have revealed that these B vitamins influence a vast spectrum of human health and disease, including cognitive function, cardiovascular health, gastric bypass recovery, neural tube defects, and even cancer.

4 Aug 2025

FAU experts recommend high-potency statins to reduce LDL cholesterol

There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease.

31 Jul 2025

The Mount Sinai Hospital named among nation’s top 20 for care excellence

The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication's "Honor Roll."

29 Jul 2025

Warfarin use not linked to higher brain bleed risk after falls in older adults

There are about 70 million baby boomers in the United States, many now over age 65. As people age, rates of cardiovascular and cerebrovascular diseases rise, leading to more use of blood thinners such as warfarin.

29 Jul 2025

Exonate plans 'CLEAR-DE' Phase IIb clinical trial of lead candidate EXN407 for diabetic eye disease

Exonate Ltd., a biotechnology company developing novel, non-invasive, small-molecule therapeutics for patients with retinal vascular diseases, today announced plans to initiate a Phase IIb clinical trial for its lead candidate EXN407.

29 Jul 2025

Brain’s blood vessels and immune cells play key role in Alzheimer’s and stroke

The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians-controlling what enters, cleaning up waste, and protecting it from threats by forming the blood-brain barrier.

28 Jul 2025

Cardiologists urged to prioritize potent statins in managing LDL cholesterol

28 Jul 2025

Study: Formal education does not slow brain aging or cognitive decline

An international study published in the journal Nature Medicine casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging.

28 Jul 2025

Promising new male birth control pill could be taken every three days

YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.

28 Jul 2025

Addressing avoidable hospitalizations in terminally ill nursing home residents

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

25 Jul 2025

Blocking nutrient scavenging weakens pancreatic tumor defenses

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions.

24 Jul 2025

High-resolution whole-cortex imaging reveals neurovascular dynamics in awake mice

Neurovascular coupling (NVC) is the dynamic regulation of cerebral blood flow in response to neural activity. Specifically, when neurons become active, nearby blood vessels dilate to increase blood supply, thereby meeting the heightened energy demands associated with neural activity.

24 Jul 2025

Study reveals pandemic life made brains age faster, even without catching COVID-19

The COVID-19 pandemic accelerated biological brain aging in older adults by an average of 5.5 months over less than three years, regardless of infection status. Social disruption, age, male sex, and socioeconomic disadvantage heightened vulnerability, while only infected individuals showed measurable declines in executive function.

23 Jul 2025

Oral microbiome changes explain blood pressure reduction from beetroot juice

The blood pressure lowering effect of nitrate-rich beetroot juice in older people may be due to specific changes in their oral microbiome, according to the largest study of its kind.

23 Jul 2025

Intranasal insulin safely and effectively reaches key memory regions of the brain

A groundbreaking brain imaging study from Wake Forest University School of Medicine confirms a vital step toward new Alzheimer's disease treatments: Intranasal insulin, delivered via a simple nasal spray, safely and effectively reaches key memory regions of the brain in older adults.

23 Jul 2025

GLP-1 receptor agonists linked to lower dementia risk in type 2 diabetes

GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of its kind, published in the open access journal BMJ Open Diabetes Research & Care.

22 Jul 2025