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Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

New tests based on biomarkers may improve diagnosis and treatment of acute kidney injury

Hospital inpatients who develop an acute kidney injury (AKI) generally fare poorly after being discharged, and have few options for effective treatment.

24 May 2023

Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Research investigates the effectiveness of oral antiviral medications, Molnupiravir and Nirmatrelvir-Ritonavir, in treating patients with type 2 diabetes and mild to moderate COVID-19. The study aims to determine the efficacy of these medications in reducing adverse outcomes in this specific population.

24 May 2023

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Chronic obstructive pulmonary disease patients newly prescribed non-benzodiazepine benzodiazepine receptor agonists (NBZRAs) such as zolpidem (Ambien, Intermezzo and other brands), a class of hypnotic drugs prescribed for insomnia, did not have an increased risk of exacerbations requiring hospitalizations or of death than those prescribed other types of hypnotics, according to research published at the ATS 2023 International Conference.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

Cannabis use, emotions, and mental health: Unraveling the young adult connection

Emotion dysregulation mediates the association between cannabis use and mental health in young adults, with sex-dependent effects observed in female users. Interventions targeting emotion dysregulation are crucial for improving mental health outcomes in female, young adult cannabis users.

23 May 2023

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

An international clinical trial co-led by UCL (University College London) researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis.

23 May 2023

New intervention program can help reduce opioid use for chronic pain

Researchers at the University of Warwick and The James Cook University Hospital, Middlesbrough have led a clinical trial, funded by the National Institute for Health and Care Research (NIHR), on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain.

23 May 2023

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

To commemorate World Schizophrenia Awareness Day, we spoke to three researchers from the Queensland Brain Institiute about their research, and why it is so important to raise awareness around Schizophrenia

23 May 2023

Academic paper: AI is advantageous in all aspects of new drug research and development

Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded.

23 May 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

California’s fentanyl problem is getting worse

California has allocated more than $1 billion in recent years to combat its opioid crisis. Much of the money has been used to distribute fentanyl test strips and the overdose reversal drug naloxone, as well as deliver medical care to people who are homeless.

23 May 2023

Modified version of anti-nausea drug can enter into cells and provide long-lasting pain relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

22 May 2023

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

research paper presents a perspective on tackling the healthcare challenge of Alzheimer's disease (AD) by shifting focus to pre-dementia stages and advocating for personalized medicine through improved diagnosis, prediction, and prevention strategies, empowering patients to actively manage their health and delay the onset of dementia.

22 May 2023

Cannabis users' cognitive abilities compared: Flower vs. concentrate - surprising findings revealed!

Study compares the cognitive test performance of chronic cannabis flower users, concentrate users, and non-users, revealing that both flower and concentrate users exhibit poorer performance in certain cognitive tasks compared to non-users. However, there were no significant differences in cognitive test results between flower and concentrate users, suggesting similar cognitive impacts under sober conditions.

22 May 2023

Study examines the role of hydrocortisone in the management of adult patients with septic shock

Sepsis is a global health priority affecting 55 million patients worldwide and causing 11 million deaths annually. Treatment for sepsis may include prompt recognition, source control, antibiotics, fluids, vasopressors, and adjunctive therapies.

22 May 2023

Drugs News and Research

Combination of genetic and environmental factors increases the risk of cleft lip

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

New tests based on biomarkers may improve diagnosis and treatment of acute kidney injury

Oral antivirals Molnupiravir and Nirmatrelvir-Ritonavir lower COVID-19 risks in type 2 diabetes patients

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Looking at cancer drugs to help put the brakes on classic indicators of aging

The antimicrobial potential of nanoparticles

Cannabis use, emotions, and mental health: Unraveling the young adult connection

International clinical trial to evaluate new combinations of generic antibiotics for treating neonatal sepsis

New intervention program can help reduce opioid use for chronic pain

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

Academic paper: AI is advantageous in all aspects of new drug research and development

Study findings offer hope for the development of novel treatments for leishmaniasis

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

California’s fentanyl problem is getting worse

Modified version of anti-nausea drug can enter into cells and provide long-lasting pain relief

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

Cannabis users' cognitive abilities compared: Flower vs. concentrate - surprising findings revealed!

Study examines the role of hydrocortisone in the management of adult patients with septic shock

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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