Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Defects in gene called RyR2 cause malfunctions in the heart's electrical system

Mayo Clinic researchers have identified defects in a second gene called RyR2 that causes malfunctions in the heart's electrical system and contributes to what were previously unexplained drownings.

2 May 2005

Angiogenesis : Blocking tumor growth and treating infarction - a new target

Our tissues are able to form new blood vessels throughout life. This mechanism, which is called angiogenesis, is essential notably in the case of myocardial infarction, stroke and limb ischemia. The very same mechanism, however, keeps tumors supplied with nutrients and oxygen thus enabling them to continue growing.

27 Apr 2005

Breakthrough technology that identifies molecular markers in early lung cancer

The new technology, created in collaboration with SEQUENOM, developers of genetic analysis products, and Methexis Genomics, uses a DNA analysis technique called methylation profiling to detect cells in the lung that are likely to become cancerous.

23 Apr 2005

Genes influence how heart failure patients respond to drugs

Genes dictate the color of our hair and eyes. They factor into whether we get cancer or heart disease. And, scientists increasingly recognize, they also ensure some patients will benefit from a prescription drug, while others develop adverse reactions or simply fail to respond at all.

21 Apr 2005

Breakthrough technology to detect cancer

Researchers at the University of Liverpool have developed a breakthrough technology that identifies molecular markers in early lung cancer.

20 Apr 2005

Common genetic mutation that increases the risk of inheriting Hirschsprung disease

Gene hunters at Johns Hopkins have discovered a common genetic mutation that increases the risk of inheriting a particular birth defect not by the usual route of disrupting the gene's protein-making instructions, but by altering a regulatory region of the gene. Although the condition, called Hirschsprung disease, is rare, its complex genetics mimics that of more common diseases, such as diabetes and heart disease.

13 Apr 2005

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

A team of scientists from Colombia, the United States and elsewhere has successfully completed a 15-year-plus search for the genetic problems behind the very rare Roberts syndrome, whose physical manifestations often include cleft lip and palate and shortened limbs that resemble those of babies whose mothers took thalidomide during pregnancy.

11 Apr 2005

Researchers set a new standard in the design and engineering of nuclear hormone receptor-based genetic on-off switches

Researchers at the University of Illinois at Urbana-Champaign have set a new standard in the design and engineering of nuclear hormone receptor-based genetic on-off switches, without causing new problems or aggravating existing ones.

7 Apr 2005

Genomics and proteomics to increase the efficiency of drug discovery and development

While the United Sates is still the world leader, Europe is having a good deal of success in the field of advanced genomics and proteomics research. Significant government funding together with the presence of large pharmaceutical companies has made Europe a major competitor in the efforts to deploy genomics and proteomics as vital tools in drug discovery and development.

5 Apr 2005

Researchers show role of Epstein-Barr virus in cancer

Researchers at the University of Toronto have mapped the molecular details that show how a viral protein coded in the Epstein-Barr virus immortalizes cells and causes them to continuously grow, thereby predisposing people to certain types of cancer.

3 Apr 2005

Gene variations explain drug dose required to control seizures

Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London.

28 Mar 2005

Latest findings in male reproduction research

The XVIII North American Testis Workshop, chaired by Population Council senior scientist Matthew Hardy, will be held 30 March - 2 April in Seattle, Washington. Participants will discuss findings from the large body of recent research on male reproduction.

28 Mar 2005

Genetically modified plants are to be used to fight against HIV, tuberculosis, diabetes and rabies

Genetically modified (GM) plants are to be used to grow vaccines for use in the worldwide fight against HIV, tuberculosis, diabetes and rabies thanks to a grant of 12 million euros from the EU’s Sixth Framework Programme (FP6).

21 Mar 2005

New biocentre which will revolutionise the way future medicines are produced

The University of Manchester has been awarded £6m to open a new biocentre which will revolutionise the way future medicines are produced – making them safer and more effective.

From The University of Manchester 14 Mar 2005

Genetic examinations of trauma, burn victims produce consistent results

A genetic tool with the potential to identify which trauma and burn patients are most likely to become seriously ill has worked consistently in a wide range of experimental clinical settings - an important hurdle to overcome before the method is routinely used in emergency rooms and intensive care units.

7 Mar 2005

Air Genome Project to sample air using whole genome shotgun sequencing

The J. Craig Venter Institute is launching a pilot project to better understand the diversity of microbes in urban air. In addition to more deeply characterizing the microbes we breathe every day, researchers anticipate that the results will provide information vital to designing systems that detect potentially dangerous biological substances in the air.

7 Mar 2005

Definitive evidence that TRPV3 is a temperature sensor

The human brain is like a general in a bunker. Floating in its bubble of cerebrospinal fluid, it has no direct window to the outside world, so the only way for the brain to observe, comprehend, and order the body into action is to rely on information it receives.

6 Mar 2005

Project targeting the increasing resistance of some viruses to drugs

A new project targeting the increasing resistance of some viruses to drugs is being funded with the help of nine million euros under the Life Sciences, Genomics and Biotechnology for Health area of the EU’s Framework Programme.

28 Feb 2005

Protein to protein interaction map for a better insight in cancer development

With the completion of the genome sequence of a number of organisms, analysis of the gene products, the proteins, is the on-going challenge.

28 Feb 2005

Cutting edge technology identifies genes that are involved in the development of Alzheimer's disease

Phoenix-Researchers at the Translational Genomics Research Institute (TGen) and Kronos Science Laboratories, an affiliate of Phoenix-based Kronos Optimal Health Company, have initiated a study with unprecedented power to identify genes that are involved in the development of Alzheimer's disease, the most common form of disabling memory and thinking problems in older persons.

24 Feb 2005