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University of Sheffield and Pfizer launch new consortium to accelerate development of ATMPs

The University of Sheffield and Pfizer have today (23 November 2020) launched a new consortium which aims to standardize and accelerate the development of Advanced Therapy Medicinal Products (ATMPs), allowing potentially transformative treatments to reach patients sooner.

23 Nov 2020

Early, late stages of neurodegeneration are distinct, finds study

Rice University biochemists Michael Stern and James McNew have studied how neurodegeneration kills cells.

23 Nov 2020

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly their hunter toxin may hold answers to better control of chronic pain.

23 Nov 2020

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Nearly a year since the world first learned of the novel coronavirus disease 2019, COVID-19, many questions remain about SARS-CoV-2, the virus behind this pandemic: Where did it come from, how did it spread so widely and rapidly, and how can we stop similar outbreaks in the future?

23 Nov 2020

Understanding biomolecular frustration could help design better drugs

Knowing precisely where proteins are frustrated could go a long way toward making better drugs.

23 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

Reprogramming T cells into highly active 'super immune cells' can improve immunotherapy benefits

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

23 Nov 2020

UNC scientists find brain cells that help drive arousal responses to strong emotions

Strong emotions such as fear and anxiety tend to be accompanied and reinforced by measurable bodily changes including increased blood pressure, heart rate and respiration, and dilation of the eyes' pupils. These so-called "physiological arousal responses" are often abnormally high or low in psychiatric illnesses such as anxiety disorders and depression.

23 Nov 2020

New algorithm accurately predicts outcomes for COVID-19 patients

With communities across the nation experiencing a wave of COVID-19 infections, clinicians need effective tools that will enable them to aggressively and accurately treat each patient based on their specific disease presentation, health history, and medical risks.

23 Nov 2020

Study: High blood sugar may worsen COVID-19 outcomes and mortality rates for non-diabetics

Abnormally high blood sugar may worsen outcomes and mortality rates for COVID-19 patients, including those without diabetes, according to major research published in the peer-reviewed open access journal Annals of Medicine.

23 Nov 2020

Women have better survival rates after lung cancer surgery than men, study shows

There are known differences in the survival rates of women and men with lung cancer. Researchers at Karolinska Institutet in Sweden set out to investigate potential reasons behind this disparity, such as the presence of other underlying diseases and smoking status.

23 Nov 2020

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Researchers in Brazil have reported two cases of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding infectious virus for a significantly longer period than has previously been reported.

23 Nov 2020

Repeat infection following COVID-19 recovery may not pose risk to close contacts

Researchers in China have conducted a study suggesting that people who have recovered from coronavirus disease 2019 (COVID-19) may not pose a risk to close contacts if they become reinfected with the causative agent severe acute respiratory syndrome coronavirus (SARS-CoV-2).

23 Nov 2020

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Excessive calcium contributes to harmful inflammation in ischemic stroke, and targeting it may provide doctors with a new way to improve patient outcomes, new research from the University of Virginia School of Medicine suggests.

23 Nov 2020

Leptin plays a strong role in controlling the body weight of children

Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin.

23 Nov 2020

Medicaid expansion may lead to earlier diagnosis, improved care for colon cancer patients

The Affordable Care Act's Medicaid expansion for low-income people appears to lead to earlier diagnosis of colon cancer, enhanced access to care, and improved surgical care for patients with this common cancer, researchers report in a new study.

23 Nov 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Fish odor syndrome (trimethylaminuria) is a debilitating disease, in which the liver cannot break down the smelly chemical trimethylamine which is produced by enzymes from bacteria residing in the gut leaving people with a fish like odor.

23 Nov 2020

Nasal dryness could be an early warning sign of COVID-19

A new study published by an international team of researchers on the preprint medRxiv* server in November 2020 details the nasal symptoms that are associated with anosmia and ageusia (loss of smell and taste) in coronavirus disease 2019 (COVID-19), including the early warning signs of infection.

23 Nov 2020

COVID-19 cases likely to increase to 20 million in the U.S. by end of January 2021

President-elect Joe Biden has signaled that fighting the COVID-19 pandemic will be an immediate priority for his administration. He recently announced a coronavirus advisory board of infectious disease researchers and former public health advisers along with an updated strategy that will include increases in testing and contact tracing, as well as transparent communication.

23 Nov 2020

Research News and Research

University of Sheffield and Pfizer launch new consortium to accelerate development of ATMPs

Early, late stages of neurodegeneration are distinct, finds study

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Understanding biomolecular frustration could help design better drugs

FDA expands approved indication for influenza treatment to include post-exposure prevention

Reprogramming T cells into highly active 'super immune cells' can improve immunotherapy benefits

UNC scientists find brain cells that help drive arousal responses to strong emotions

New algorithm accurately predicts outcomes for COVID-19 patients

Study: High blood sugar may worsen COVID-19 outcomes and mortality rates for non-diabetics

Women have better survival rates after lung cancer surgery than men, study shows

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Repeat infection following COVID-19 recovery may not pose risk to close contacts

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Leptin plays a strong role in controlling the body weight of children

Medicaid expansion may lead to earlier diagnosis, improved care for colon cancer patients

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Scientists make breakthrough in studying the enzyme involved in fish odor syndrome

Nasal dryness could be an early warning sign of COVID-19

COVID-19 cases likely to increase to 20 million in the U.S. by end of January 2021

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