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XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Prebiotic inulin may ease muscle loss in burn victims, study suggests

Inulin supplementation was found to mitigate gut microbiota dysbiosis and skeletal muscle atrophy in rats with severe burns, suggesting a promising approach for improving burn recovery outcomes.

30 Jan 2024

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

Dr. Jeannine Gerhardt, an assistant professor of stem cell biology in obstetrics and gynecology and in reproductive medicine at Weill Cornell Medicine, has received a five-year, $2.1 million grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, for the study of repetitive DNA and RNA sequences and the mechanisms by which they cause cell dysfunction and diseases.

30 Jan 2024

Vegan and keto diets trigger distinct immune system changes in just two weeks

Researchers at the National Institutes of Health observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (also called keto) diet.

30 Jan 2024

Gut microbiome may hold key to fighting common respiratory viruses

The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

30 Jan 2024

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

30 Jan 2024

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

30 Jan 2024

Resin ingredient strongly decreases coronavirus infectivity on plastic surfaces

Researchers at the University of Jyväskylä, Finland, are currently developing anti-viral surfaces to decrease the spread of infectious diseases.

30 Jan 2024

Cambridge scientists discover how fasting turns up the body's natural inflammation fighter

Cambridge scientists may have discovered a new way in which fasting helps reduce inflammation – a potentially damaging side-effect of the body's immune system that underlies a number of chronic diseases.

30 Jan 2024

Nature walk enhances certain executive control processes in the brain

New research from University of Utah psychology researchers is helping prove what American authors John Muir and Henry David Thoreau tried to teach more than 150 years ago: Time spent in nature is good for the heart and soul.

30 Jan 2024

Genetic blueprint revealed: New insights into thyroid cancer's resistance and transformation

A new research perspective was published in Oncotarget's Volume 15 on January 24, 2024, entitled, "Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation."

30 Jan 2024

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

There are many lingering mysteries from the COVID-19 pandemic. For instance, why does SARS-CoV-2, the virus behind the disease, cause severe symptoms in some patients, while many other coronaviruses don't? And what causes strange symptoms to persist even after the infection has been cleared from a person's system?

30 Jan 2024

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.

30 Jan 2024

New drug kills tumor cells by triggering a deadly calcium storm

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Hydroxyurea treatment can greatly benefit children with sickle cell anemia, study reveals

Clinical research led by Indiana University School of Medicine investigators and their collaborators in Uganda has revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia.

29 Jan 2024

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs.

29 Jan 2024

Gene variant linked to increased miscarriage risk through disrupted chromosome pairing

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

29 Jan 2024

Blood chip could offer early insights into cancer treatment effectiveness

Using a chip to process blood samples, doctors can monitor the amount of cancer cells in a patient’s blood to determine how well a treatment is working by the fourth week, according to a new University of Michigan study.

29 Jan 2024

B Cell News and Research

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

Prebiotic inulin may ease muscle loss in burn victims, study suggests

Weill Cornell Medicine researcher wins $2.1 million grant to study repetitive DNA and RNA sequences

Vegan and keto diets trigger distinct immune system changes in just two weeks

Gut microbiome may hold key to fighting common respiratory viruses

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Resin ingredient strongly decreases coronavirus infectivity on plastic surfaces

Cambridge scientists discover how fasting turns up the body's natural inflammation fighter

Nature walk enhances certain executive control processes in the brain

Genetic blueprint revealed: New insights into thyroid cancer's resistance and transformation

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

New drug kills tumor cells by triggering a deadly calcium storm

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Hydroxyurea treatment can greatly benefit children with sickle cell anemia, study reveals

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Gene variant linked to increased miscarriage risk through disrupted chromosome pairing

Blood chip could offer early insights into cancer treatment effectiveness

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