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Alcohol alters prefrontal cortex activity through ion channel disruption

The prefrontal cortex (PFC) region of the brain is involved in decision making. New rodent findings show that PFC neuron N-methyl-D-aspartic acid (NMDA) receptors are especially sensitive to concentrations of alcohol achieved during drinking.

4 Apr 2008

Proteolix's Carfilzomib granted orphan drug designation

Proteolix, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to carfilzomib, a selective blocker of proteasome activity for the treatment of multiple myeloma.

3 Apr 2008

Obese pregnant women use more health care services

Obesity during pregnancy is associated with greater use of health care services and longer hospital stays, according to a study from the Centers for Disease Control and Prevention (CDC) and Kaiser Permanente Northwest Center for Health Research.

3 Apr 2008

Fluorodeoxyglucose positron emission tomography to help determine whether cognitive impairment will lead to Alzheimer's

With nearly 10 million baby boomers at risk for developing Alzheimer's disease, researchers are taking a closer look at a condition known as mild cognitive impairment.

3 Apr 2008

Increased risk of myocardial infarction and diabetes in East Germany

More people suffer from overweight, high blood pressure and metabolic disturbances in East Germany than in West Germany.

3 Apr 2008

Genetic variations raise lung cancer risk for smokers and ex-smokers

Two common inherited genetic variations are associated with increased risk of lung cancer for smokers and former smokers, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports April 2 in the online edition of Nature Genetics.

3 Apr 2008

Health effects of drinking tea

Tea drinkers who opt for black, oolong, green or white teas may find that these beverages offer health benefits.

3 Apr 2008

De-marrowing helps bones mend faster

Could you strengthen bones and speed up recovery after fractures and breaks simply by removing some bone marrow with a syringe?

3 Apr 2008

A daily dose of caffeine may help protect against Alzheimer's

A daily dose of caffeine blocks the disruptive effects of high cholesterol that scientists have linked to Alzheimer's disease.

3 Apr 2008

Myth about drinking copius amounts of water debunked

Scientists in the United States say there is little evidence that drinking lots of water improves the health.

3 Apr 2008

Free vascular health checks for the over 40's promises to save 2,000 lives each year

A scheme whereby everyone between the age of 40 to 74 will be given free health screening for vascular diseases is to be introduced in Britain next year.

3 Apr 2008

Cellular grafting procedure helps young patients with knee disorder get active

At 14 years old, Adam Vasser of Los Altos, Calif., was an active kid who loved baseball.

2 Apr 2008

New clues to risk of Hodgkin lymphoma discovered

A long-term study of twins has led University of Southern California (USC) researchers to find potential links between Hodgkin lymphoma and levels of an immune response protein (interleukin-12).

2 Apr 2008

Satoris enters collaboration to validate early Alzheimer's test

Satoris, Inc., a molecular diagnostics company focused on developing blood-based tests for Alzheimer ' s disease, will shortly begin a collaborative study with the Mayo Foundation for Medical Education and Research (Mayo Clinic) to validate the utility of plasma biomarkers for early detection of mild to moderate Alzheimer ' s disease.

2 Apr 2008

Angioplasty and stenting for renal artery lesions

The largest-ever randomized study to evaluate the effectiveness of catheter-based interventions in patients with narrowing of the renal artery has shown that angioplasty and stenting offer no benefit over medical therapy.

2 Apr 2008

Bosentan drugs offers new approach to limiting organ damage in sickle cell disease

Sickle cell disease (SCD) is so called because of the abnormal sickle shape of the red blood cells in individuals with this blood disorder.

2 Apr 2008

Synthetic progestin linked to breast cancer

Millions of post-menopausal women use hormone replacement therapy (HRT) as a method to reduce symptoms associated with menopause.

2 Apr 2008

Rimonabant shows mixed results for slowing progression of coronary disease

The anti-obesity medication rimonabant showed mixed results in slowing progression of coronary artery disease in patients with abdominal obesity and pre-existing coronary disease, according to a new study in the April 2 issue of JAMA.

2 Apr 2008

Potential link found between bacteria found in the human digestive system and obesity

Obesity is more than a cosmetic concern because it increases a person's risk for developing high blood pressure, diabetes and many other serious health problems.

2 Apr 2008

ExoSeal vascular plug gets good reviews in ECLIPSE study

A new bioabsorbable plug that seals the arterial puncture site used for threading catheters into the body during diagnostic angiography and interventional procedures significantly shortens bleeding time and enables patients to get up and walk around far sooner than when manual compression is applied to the groin.

2 Apr 2008