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How does the nasal cavity's immune system combat SARS-CoV-2?

Researchers discovered that CD4+ and CD8+ T cells play a crucial role in clearing COVID-19 infection in the nasal cavity but have limited impact on lung infections, with implications for understanding and treating the virus.

28 Jan 2024

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

New brain implant records neuron activity for months

Recording the activity of large populations of single neurons in the brain over long periods of time is crucial to further our understanding of neural circuits, to enable novel medical device-based therapies and, in the future, for brain–computer interfaces requiring high-resolution electrophysiological information.

27 Jan 2024

Exploring pharmacological, non-pharmacological, and stem cell therapies for treatment of autism spectrum disorders

A research study, led by Maurizio Battino and Francesca Giampieri, with a group of researchers from the Universidad Europea del Atlántico (European University of the Atlantic, UNEATLANTICO), published in the journal "Pharmacological Research", studies various pharmacological, non-pharmacological, and stem cell therapies for the treatment of autism spectrum disorders.

27 Jan 2024

Gene activity plays key role in immune cell production, study shows

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19.

27 Jan 2024

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

Scientists at La Jolla Institute for Immunology (LJI) have found direct evidence that exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2. In fact, prior exposure to a common cold coronavirus appears to partially protect mice from lung damage during a subsequent SARS-CoV-2 infection.

27 Jan 2024

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

27 Jan 2024

Research upends understanding of circadian clock in melanoma

A Ludwig Cancer Research study has found that the circadian clock - which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive - in fact has a contextually variable role in cancer.

27 Jan 2024

New study of daylight vision using canine model offers critical insight into restoring cone function

In the retinas of human eyes, the cones are photoreceptor cells responsible for color vision, daylight vision, and the perception of small details.

27 Jan 2024

Female reproductive characteristics may be overlooked as risk factors for later metabolic dysfunction

A new review of available evidence led by researchers at the Harvard Pilgrim Health Care Institute suggests that female reproductive characteristics may be overlooked as risk factors that contribute to later metabolic dysfunction.

27 Jan 2024

HIV virus found to possess hidden transport ability

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system's ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

27 Jan 2024

Mutation butterfly effect: Study reveals how single change triggers autism gene network

Researchers in the RIKEN Center for Brain Science (CBS) examined the genetics of autism spectrum disorder (ASD) by analyzing mutations in the genomes of individuals and their families.

27 Jan 2024

Growing meat with built-in growth factors cuts costs

Cellular agriculture – the production of meat from cells grown in bioreactors rather than harvested from farm animals – is taking leaps in technology that are making it a more viable option for the food industry.

27 Jan 2024

Low-dose radiation shows promise as treatment for brain injury and stroke

Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.

27 Jan 2024

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

27 Jan 2024

Mapping the neural pathways of thirst and salt satiety

Staying hydrated and consuming appropriate amounts of salt is essential for the survival of terrestrial animals, including humans.

27 Jan 2024

Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.

26 Jan 2024

Study offers insights into who's at risk for long COVID among immunocompromised patients

Early in the pandemic, clinicians noticed that certain immunocompromised patients were experiencing persistent SARS-CoV-2 infections, some lasting weeks to months at a time.

26 Jan 2024

Johns Hopkins scientists unravel mystery of retinal cell communication

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

25 Jan 2024

B Cell News and Research

How does the nasal cavity's immune system combat SARS-CoV-2?

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

New brain implant records neuron activity for months

Exploring pharmacological, non-pharmacological, and stem cell therapies for treatment of autism spectrum disorders

Gene activity plays key role in immune cell production, study shows

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

Research upends understanding of circadian clock in melanoma

New study of daylight vision using canine model offers critical insight into restoring cone function

Female reproductive characteristics may be overlooked as risk factors for later metabolic dysfunction

HIV virus found to possess hidden transport ability

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Mutation butterfly effect: Study reveals how single change triggers autism gene network

Growing meat with built-in growth factors cuts costs

Low-dose radiation shows promise as treatment for brain injury and stroke

Prime editing takes gene therapy to the next level

Mapping the neural pathways of thirst and salt satiety

Sclerostin may protect against heart disease in patients with type 2 diabetes

Study offers insights into who's at risk for long COVID among immunocompromised patients

Johns Hopkins scientists unravel mystery of retinal cell communication

Using single B cell screening to boost antibody discovery eBook

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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