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Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

Phosphatases of regenerating liver (PRLs) are a family of enigmatic proteins involved in cell growth and metabolism present in various species.

15 May 2023

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

University of Arizona Health Sciences researchers are taking the foot off the brake in their quest to improve opioid therapy while decreasing its side effects.

15 May 2023

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor.

15 May 2023

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.

15 May 2023

Humanized mouse model for rare genetic disease developed for the first time

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

15 May 2023

Study finds that caffeine consumption was associated with nicotine use onset among early adolescents

Researchers examined the contribution of caffeine to nicotine use onset during early adolescence.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Pioneering focused ultrasound trial shows promising results for patients with Parkinson’s disease

The findings of a major international trial to test a high-tech, scalpel-free approach to treating movement problems caused by Parkinson’s disease have been published in the prestigious New England Journal of Medicine.

13 May 2023

Former anabolic steroid users more likely to develop heart disease

Anabolic steroids not only can cause serious side effects during use, such as heart failure and depression, but can continue being harmful years after stopping, according to two studies presented at the 25th European Congress of Endocrinology in Istanbul.

13 May 2023

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).

12 May 2023

AI used to build a 3D model of the Commander complex

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

11 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

New antimicrobial coating material effectively kills bacteria and viruses

Researchers have used a common disinfectant and antiseptic to create a new antimicrobial coating material that effectively kills bacteria and viruses, including MRSA and Covid-19.

11 May 2023

Medicines for All Institute at VCU receives $18.7 million grant to improve access to medicines

The Medicines for All Institute at Virginia Commonwealth University will work on 14 new global health projects and expand its capabilities to improve access to medicines around the world thanks to an $18.7 million grant from the Bill & Melinda Gates Foundation.

11 May 2023

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

An important genetic mechanism of drug resistance in one of the deadliest human malaria parasites has been identified in a new study published in Nature Microbiology.

11 May 2023

Drugs News and Research

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Phosphatases of regenerating liver play a unique role in the growth and spread of cancers

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Study reveals how serotonin affects animal behavior at the whole-brain scale

Newly identified genetic variant provides protection from Alzheimer's disease

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

Humanized mouse model for rare genetic disease developed for the first time

Study finds that caffeine consumption was associated with nicotine use onset among early adolescents

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Pioneering focused ultrasound trial shows promising results for patients with Parkinson’s disease

Former anabolic steroid users more likely to develop heart disease

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

AI used to build a 3D model of the Commander complex

Targeting the hemoglobin problem in sickle cell disease using a new drug

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

New antimicrobial coating material effectively kills bacteria and viruses

Medicines for All Institute at VCU receives $18.7 million grant to improve access to medicines

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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