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Diltiazem reduces cocaine cravings in a rat model

Researchers from Boston University School of Medicine and Harvard Medical School have found that diltiazem, a drug used in the treatment of high blood pressure, reduces cocaine cravings in a rat model.

28 Feb 2008

New blood biomarker accurately predicts spread of prostate cancer to regional lymph nodes

Researchers report finding a new blood biomarker that enables close to 98 percent accuracy in predicting the spread of prostate cancer to regional lymph nodes.

28 Feb 2008

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.

28 Feb 2008

New view of human brainstem

A team of scientists from Princeton University has devised a new experimental technique that produces some of the best functional images ever taken of the human brainstem, the most primitive area of the brain.

28 Feb 2008

Ginkgo biloba and dementia

Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems, according to a study published in the February 27, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Feb 2008

Are cataract rates on the decline?

Should glaucoma patients seeking alternative therapies trust what they find online? Are seatbelts still important to protect eyes in auto accidents, now that most cars have airbags? What's the connection between hearing loss and one form of glaucoma? These are among the topics explored in the March 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

28 Feb 2008

Hormones produced by the heart eliminate pancreatic cancer in mice

Hormones produced by the heart eliminated human pancreatic cancer in more than three-quarters of the mice treated with the hormones and eliminated human breast cancer in two-thirds of the mice, according to researcher David Vesely, a doctor at the James A. Haley Veterans Hospital in Tampa and a professor at the University of South Florida (USF).

27 Feb 2008

Risks of CVD for COX-2 inhibitors lower than previously reported

In an article published in the March issue of the Journal of Cardiovascular Pharmacology and Therapeutics, researchers from Florida Atlantic University (FAU) assess the totality of evidence, including strengths and limitations of different types of evidence contributing to the debate about cardiovascular disease (CVD) risks of cyclooxygenase-2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

27 Feb 2008

RFID technology to secure donor blood supply

Radio frequency identification technology, or RFID, has inspired many novel applications of late, including efforts to study magazine reader patterns, access restricted areas, locate stolen vehicles and track luggage at major airports.

27 Feb 2008

Protein that stimulates blood vessel growth worsens ovarian cancer

A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

27 Feb 2008

New understanding of structure and behavior of collagen

The structure and behavior of one of the most common proteins in our bodies has been resolved at a level of detail never before seen, thanks to new research performed at the Advanced Photon Source (APS) at the U.S. Department of Energy's (DOE) Argonne National Laboratory.

27 Feb 2008

New Alzheimer's patent by Affiris

Affiris GmbH has secured another Europe-wide patent for an innovative method of treating Alzheimer's disease. This new blood-cleansing method is similar to dialysis and is designed to reduce the amount of harmful protein deposits in the brain. It is based on the AFFITOME technology established by Affiris, which was patented in October 2007 for an Alzheimer's vaccine.

27 Feb 2008

Minimally invasive fibroid treatment fares well in multicenter trial

A new multicenter trial found that uterine artery embolization (UAE) is a good alternative to hysterectomy in women with symptomatic fibroids.

27 Feb 2008

IRIS International completes study of 85 post-prostatectomy patients using investigational NADiA PSA assay

IRIS International Inc. has announced that its Iris Molecular Diagnostics (IMD) group has successfully completed a retrospective study of stored leftover serum of 85 post-prostatectomy patients, men who had their prostate removed due to prostate cancer, using its investigational NADiA (Nucleic Acid Detection ImmunoAssay) PSA Assay.

27 Feb 2008

Drug for anemic cancer patients raises risk of death

Millions of cancer patients take drugs to boost their red blood cells and health when they become anemic after chemotherapy.

27 Feb 2008

Anemia drug linked to blood clots, death in cancer patients

Treating anemia with a class of drugs known as erythropoiesis-stimulating agents (ESAs) is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs) and death among patients with cancer, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases

A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Adding therapy helps adolescents with depression not responding to SSRIs

For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications, according to a study in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Tenofovir gel safe for daily use over an extended period

A vaginal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel.

27 Feb 2008

Spinal cord injury may not increase risk of heart disease

Americans who live with spinal cord injury do not appear to be at greater risk of developing carbohydrate and lipid disorders such as insulin resistance, diabetes, impaired glucose tolerance, and high or low blood cholesterol levels - risk factors for heart disease - than able-bodied persons, according to a new evidence review by HHS' Agency for Healthcare Research and Quality.

27 Feb 2008