Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

New drug improves kidney function for patients with type 2 diabetes and chronic kidney disease

A new anti-inflammatory drug used by patients with type 2 diabetes improved their kidney function during a year-long study involving researchers from UT Southwestern Medical Center.

24 Jun 2011

EMA CHMP recommends approval of linagliptin for type 2 diabetes

Boehringer Ingelheim and Eli Lilly and Company today received a positive opinion from the European Medicines Agency's (EMA) medicinal committee recommending approval of linagliptin, 5 mg, film-coated tablets (to be marketed under the trade name Trajenta® in Europe) for the treatment of adults with type 2 diabetes.

24 Jun 2011

Bristol-Myers Squibb Foundation awards grants to empower African American women with type 2 diabetes

The Bristol-Myers Squibb Foundation today awarded five grants totaling $1.5 million to organizations that will empower African American women with type 2 diabetes to better manage their disease while also leveraging their standing as leaders in their families and communities to influence the health of those around them.

24 Jun 2011

Epilepsy may arise from complex mixture of altered ion channels

Imagine two flat screen televisions tuned to the same channel and sitting side-by-side. From a distance, their pictures are virtually the same, however up close, you can see subtle variations in the pixels - one blurred here, another dropped out there.

24 Jun 2011

InVasc commences INV-144 Phase IIa trial in chronic kidney disease

InVasc Therapeutics, Inc., announced today that it has initiated a Phase IIa, proof of concept (POC), clinical trial with INV-144, a combination drug of losartan with alpha Lipoic Acid (ALA), to slow the progression of chronic kidney disease (CKD) in hypertensive diabetic patients.

24 Jun 2011

NSBRI expands use of ultrasound during spaceflights and on Earth

The remoteness and resource limitations of spaceflight pose a serious challenge to astronaut health care. One solution is ultrasound.

24 Jun 2011

New York Times examines very rare E. coli strain responsible for German outbreak

The New York Times examines the E. coli strain responsible for the recent outbreak in Germany, saying the bacteria "have a highly unusual combination of two traits and that may be what made the outbreak among the deadliest in recent history, scientists there are reporting."

24 Jun 2011

Lithium can prevent aggregation of toxic proteins and cell loss linked with Parkinson's

Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

24 Jun 2011

Two NJIT researchers receive U.S. Patent for nanoprobe array technique

Reginald C. Farrow and Zafer Iqbal, research professors at NJIT, were awarded a patent today for an improved method of fabricating arrays of nanoscale electrical probes. Their discovery may lead to improved diagnostic tools for measuring the spatial variation of electrical activity inside biological cells.

22 Jun 2011

Frequent nighttime home dialysis more effective for patients with kidney failure

Researchers at St. Michael's Hospital have found more evidence of the benefits of home dialysis for patients with kidney failure.

22 Jun 2011

Study finds high prevalence of diabetic kidney disease in the U.S.

Over the past 2 decades the prevalence of diabetic kidney disease in the U.S. increased in direct proportion to the prevalence of diabetes itself, according to a study in the June 22/29 issue of JAMA.

22 Jun 2011

First Edition: June 21, 2011

In today's headlines, the latest on the debt-reduction talks, the next chapter in the saga surrounding a McKinsey insurance survey and the details of the Obama administration's effort to tout the health law's prreventive care benefits.

22 Jun 2011

Positive results from LCP-Tacro Phase III trial in stable kidney transplant recipients

LifeCycle Pharma A/S today reported that the company's lead product candidate, LCP-Tacro, successfully demonstrated non-inferiority compared to tacrolimus in its Phase III trial, Study 3001.

21 Jun 2011

Concert to advance CTP-499, C-21191 into Phase 2 trials for diabetic nephropathy and spasticity

Concert Pharmaceuticals, Inc. announced today the advancement of two programs from its DCE Platform. CTP-499 is progressing into Phase 2 clinical trials for diabetic nephropathy and C-21191 has been selected as a lead candidate for spasticity.

20 Jun 2011

Alexion begins eculizumab clinical trial in Shiga-toxin producing E. coli hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. and Alexion Pharma International Sàrl (APIS), announced today that the Paul-Ehrlich-Institut, Germany's healthcare regulatory body for biological products, has authorized initiation of an open-label clinical trial to investigate eculizumab as a treatment for patients with Shiga-toxin producing E. coli hemolytic uremic syndrome, which has resulted from infections by Enterohemorrhagic Escherichia coli in an unusually wide outbreak in Germany that began in May.

20 Jun 2011

Study: Dyslexia gene controls cilia in brain neurons

Scientists at Karolinska Institutet in Sweden have discovered that a gene linked to dyslexia has a surprising biological function: it controls cilia, the antenna-like projections that cells use to communicate.

20 Jun 2011

Targeting activity of PKD1 may be beneficial for treatment of polycystic kidney, liver disease

A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics.

20 Jun 2011

MA launches national campaign to raise awareness on meningitis

This Father's Day is a special day for Angels Dads on Meningitis (ADOM). Angel dads from across the country came together in Denver, Colorado to launch a national campaign on meningitis awareness.

20 Jun 2011

FDA approves NULOJIX

Bristol-Myers Squibb Company announced that the U.S. Food and Drug Administration (FDA) approved NULOJIX, the first selective T-cell costimulation blocker indicated for the prophylaxis of organ rejection in adult patients receiving a kidney transplant, in combination with basiliximab induction, mycophenolate mofetil (MMF), and corticosteroids.

18 Jun 2011

High rates of type 1 diabetes in Australian children

According to a new report the rate of Type 1 diabetes in Australian children will leap by 10 per cent in the five years to 2013, cementing Australia's position in the top 10 OECD nations for the condition's prevalence. Currently the prevalence of diabetes in Australia ranks seventh-highest among the 30 OECD nations.

17 Jun 2011

Nephrology News and Research

Further Reading

New drug improves kidney function for patients with type 2 diabetes and chronic kidney disease

EMA CHMP recommends approval of linagliptin for type 2 diabetes

Bristol-Myers Squibb Foundation awards grants to empower African American women with type 2 diabetes

Epilepsy may arise from complex mixture of altered ion channels

InVasc commences INV-144 Phase IIa trial in chronic kidney disease

NSBRI expands use of ultrasound during spaceflights and on Earth

New York Times examines very rare E. coli strain responsible for German outbreak

Lithium can prevent aggregation of toxic proteins and cell loss linked with Parkinson's

Two NJIT researchers receive U.S. Patent for nanoprobe array technique

Frequent nighttime home dialysis more effective for patients with kidney failure

Study finds high prevalence of diabetic kidney disease in the U.S.

First Edition: June 21, 2011

Positive results from LCP-Tacro Phase III trial in stable kidney transplant recipients

Concert to advance CTP-499, C-21191 into Phase 2 trials for diabetic nephropathy and spasticity

Alexion begins eculizumab clinical trial in Shiga-toxin producing E. coli hemolytic uremic syndrome

Study: Dyslexia gene controls cilia in brain neurons

Targeting activity of PKD1 may be beneficial for treatment of polycystic kidney, liver disease

MA launches national campaign to raise awareness on meningitis

FDA approves NULOJIX

High rates of type 1 diabetes in Australian children

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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