Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

Alexion Pharmaceuticals, Inc. today announced the presentation of final data from the two Phase 2 studies of Soliris as a treatment for patients with atypical hemolytic uremic syndrome.

13 Jun 2011

NIH awards $1.9M grant to Scripps Research scientist for malaria study

A scientist from The Scripps Research Institute has won a four-year, $1.9 million grant from the National Institutes of Health to better understand the parasite that causes malaria, laying the groundwork to develop better drugs to combat the widespread and deadly disease.

10 Jun 2011

IBC now qualified as 'patient-centered medical homes'

Independence Blue Cross (IBC) has reached a significant milestone with 100 primary care practices with more than 1,000 physicians now qualified as "patient-centered medical homes," and announced today that it is stepping up its efforts to support this transformation of primary care.

10 Jun 2011

Metabolomics analysis shows 3IS as early predictive, sensitive biomarker of acute kidney injury

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Metabolomics Analysis Reveals Elevation of 3-Indoxyl Sulfate in Plasma and Brain during Chemically-induced Acute Kidney Injury in Mice: Investigation of Nicotinic Acid Receptor Agonists", in Toxicology and Applied Pharmacology.

9 Jun 2011

Research provides new insights into how cilia are assembled on the cell surface

Body cells detect signals that control their behavior through tiny hairs on the cell surface called cilia. Serious diseases and disorders can result when these cilia do not work properly.

9 Jun 2011

High-fat diet may cause brain nerve cell injury

Obesity among people who eat a high-fat diet may involve injury to neurons, or nerve cells, in a key part of the brain that controls body weight, according to the authors of a new animal study. The results will be presented Tuesday at The Endocrine Society's 93rd Annual Meeting in Boston.

9 Jun 2011

Isotechnika reports consolidated net loss of $2.9 million for first quarter 2011

Isotechnika Pharma Inc. today announced financial and operating results for the three months ended March 31, 2011.

9 Jun 2011

DASH diet comes out on top

DASH diet, often recommended to help adults lower their blood pressure has ranked over more popular options in a ranking of 20 diets by U.S. News & World Report. The DASH diet, the magazine concluded, was the best overall. Government approved DASH standing for Dietary Approaches to Stop Hypertension was chosen by the magazine’s panel of nutrition experts among other things, being nutritious, easy to follow and protecting against heart disease and perhaps diabetes.

8 Jun 2011

Health officials rule out sprouts as source of German E. coli outbreak

Health officials in Germany are continuing to search for the source of an E. coli outbreak after tests on suspected sprouts from a farm in the north of the country came back negative, Deutsche Welle reports. The outbreak has killed 22 people and sickened more than 2,000 (Hallam/Penfold, 6/6).

8 Jun 2011

Avoiding repetitive activities that increase stress on the joints may prevent bursitis

As warm weather arrives and the great outdoors beckons, more and more men and women will be taking to the trails, the beaches, or their yards and gardens, embarking on physical activities that may result in sore, aching, swollen joints.

8 Jun 2011

'Designer' probiotic bacterium neutralises E. coli toxin

A potential life-saving treatment for severe E. coli food poisoning outbreaks - developed more than a decade ago - hasn't gone forward into clinical trials because of lack of commercial interest.

8 Jun 2011

Low phosphate intake can reduce heart disease

Lowering phosphate intake in humans can reduce heart disease, according to research by experts at the University of Sheffield.

8 Jun 2011

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced clinical and preclinical data from its lead program, KAI-4169, at the Endocrine Society's 93rd Annual Meeting (ENDO 2011) taking place in Boston, June 4-7, 2011. KAI-4169 is a novel pharmaceutical agent being developed for the treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD).

7 Jun 2011

Unique clinical trial addresses important questions about treating AIDS-related cancers

As the world marks the 30-year anniversary of the first reporting of HIV/AIDS, now comes the realization of a new challenge for people with the incurable disease. For reasons not yet clear, people with HIV face a higher rate of cancers not usually associated with HIV. This increasing rate of "non-AIDS defining cancers" includes lung, head and neck, liver, kidney, and anal cancers, among others.

7 Jun 2011

Higher than IOM recommended Vitamin D levels required for optimizing osteoporosis, low BMD therapy

To fully optimize a drug therapy for osteoporosis and low bone mineral density (BMD), patients should maintain vitamin D levels above the limits recently recommended by the Institute of Medicine (IOM), according to a new study by researchers from Hospital for Special Surgery in New York. The study will be presented at the Endocrine Society's Annual Meeting in Boston, June 4-7.

7 Jun 2011

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Novartis announced new data today showing a significant improvement in both recurrence-free survival and overall survival for patients taking Gleevec® (imatinib mesylate)* tablets for three years after surgery to remove KIT (CD117)-positive gastrointestinal stromal tumors (KIT+ GIST) compared to one year of treatment. These data will be presented at the 47th American Society of Clinical Oncology (ASCO) plenary session on Sunday, June 5.

6 Jun 2011

New E. coli outbreak alarms Europe

An Escherichia coli (E. coli) outbreak of disease in Germany has left 22 people dead and it is alarming populations across Europe.

5 Jun 2011

Scientists find way to protect kidney from cancer drug toxicity

Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.

4 Jun 2011

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Life Technologies Corporation today announced that preliminary data from DNA sequencing performed in cooperation with the University Hospital Muenster, Germany, on the Ion Personal Genome Machine strongly suggests that the bacterium at the root of the deadly outbreak in Germany is a new hybrid type of pathogenic E. coli strains.

4 Jun 2011

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

For patients with advanced melanoma, which is the most lethal type of skin cancer, the results of a large clinical trial show that a vaccine combined with the immune-boosting drug Interleukin-2 can improve response rate and progression-free survival.

4 Jun 2011

Nephrology News and Research

Further Reading

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

NIH awards $1.9M grant to Scripps Research scientist for malaria study

IBC now qualified as 'patient-centered medical homes'

Metabolomics analysis shows 3IS as early predictive, sensitive biomarker of acute kidney injury

Research provides new insights into how cilia are assembled on the cell surface

High-fat diet may cause brain nerve cell injury

Isotechnika reports consolidated net loss of $2.9 million for first quarter 2011

DASH diet comes out on top

Health officials rule out sprouts as source of German E. coli outbreak

Avoiding repetitive activities that increase stress on the joints may prevent bursitis

'Designer' probiotic bacterium neutralises E. coli toxin

Low phosphate intake can reduce heart disease

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

Unique clinical trial addresses important questions about treating AIDS-related cancers

Higher than IOM recommended Vitamin D levels required for optimizing osteoporosis, low BMD therapy

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

New E. coli outbreak alarms Europe

Scientists find way to protect kidney from cancer drug toxicity

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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