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Scientists develop new drug to outflank cancer resistance

A new drug has shown promising results against breast and prostate cancer cells and tumours that are resistant to conventional hormone-based treatments, according to research published in the British Journal of Cancer.

12 Dec 2007

Better health outcomes in hospitals using information technology

Patients are more likely to have better health outcomes if they are treated at hospitals using information technology (IT) systems, according to a comprehensive new Florida State University study.

12 Dec 2007

Exercise testing to predict mitral regurgitation

In as many as one in five people over age 55, when the heart contracts to send blood around the body, some degree of backward leakage occurs across the mitral valve, a condition known as mitral regurgitation (MR).

12 Dec 2007

Human hormone shows potential as new antidepressant agent

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains.

12 Dec 2007

Epigenomic test that could improve treatment for specific gastric cancers

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center in a recent issue of Journal of Clinical Oncology identifies activation of the enzyme COX-2 in gastric cancer tumors as a prognostic indicator for poor outcome.

12 Dec 2007

Exercise testing may help predict seriousness of mitral regurgitation

12 Dec 2007

Bosutinib safe, effective for chronic myelogenous leukemia

A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology.

12 Dec 2007

Data confirm Dasatinib's effectiveness in resistant chronic myelogenous leukemia

Updated clinical trial results show that the drug dasatinib (Sprycel) continues to be highly effective in patients with chronic myelogenous leukemia who were unable to tolerate Gleevec or who developed resistance to it, reports a team led by researchers at Dana-Farber Cancer Institute.

12 Dec 2007

Addition of antibiotics to MS therapy could slow down progression of the disease

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

11 Dec 2007

The key to a long and healthy life - Mediterranean diet plus regular exercise

Researchers have produced even more evidence of the benefits of a Mediterranean-style diet and regular physical activity.

11 Dec 2007

Need for education for primary care physicians on rarely seen cancers

Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates.

10 Dec 2007

Bacteria in cows' milk may cause Crohn's disease

Scientists at the University of Liverpool have found how a bacterium, known to cause illness in cattle, may cause Crohn’s disease in humans.

10 Dec 2007

Researchers uncover delicate protein balance behind the immune system response

A team of researchers from the University of Pennsylvania School of Veterinary Medicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok and attacks friendly tissue.

10 Dec 2007

Guideline for management of postmeal glucose

Christmas time is full of food when most of us simply have to worry about our expanding waist lines but new research led by the University of Warwick’s Medical School says that people with diabetes need to pay attention to the dangers of a neglected post meal peak in blood glucose.

10 Dec 2007

Patients without advance care plans more likely to die

Researchers at the University of Nebraska Medical Center (UNMC) in Omaha and the Fred Hutchinson Cancer Research Center in Seattle found only half of patients undergoing stem cell transplantation had advance care plans - documents such as living wills, power of attorney for health care, or life-support instructions - and those without plans were three times more likely to die during or after surgery.

10 Dec 2007

New therapeutic options for newly diagnosed multiple myeloma patients

Mayo Clinic researchers presented results of a phase II trial of myeloma induction therapy -- a first step therapy designed to reduce cancer cells numbers -- with cyclophosphamide, bortezomib, and dexamethasone (Cybor-D) showing an improved response over the traditional lenalidomide-dexamethasone (L-Dex) therapy.

10 Dec 2007

New technique reveals insights into lung disease

Doctors at the Universities of Leicester and Nottingham are collaborating to use a magnetic resonance technique to image and quantify the air spaces inside the lungs.

10 Dec 2007

Most adults with conditions that increase cardiovascular disease risk have hypertension

Nearly three-fourths of American adults with conditions such as coronary heart disease, stroke, diabetes or others that raise their risk for cardiovascular complications also have hypertension (high blood pressure), according to a report in the December 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Dec 2007

Hypertension associated with risk for mild cognitive impairment

High blood pressure appears to be associated with an increased risk for mild cognitive impairment, a condition that involves difficulties with thinking and learning, according to a report in the December issue of Archives of Neurology.

10 Dec 2007

Being in good shape after 40 reduces risk of stroke

People who have good physical function after the age of 40 may lower their risk of stroke by as much as 50 percent compared to people who are not able to climb stairs, kneel, bend, or lift as well, according to research published in the December 11, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

10 Dec 2007