Efficacy News and Research

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Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

A team of researchers conducted a randomized, placebo-controlled, adaptive platform trial to evaluate the efficacy of fluvoxamine to prevent COVID-19 progression and hospitalization.

29 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

More strategic COVID-19 testing can reduce reliance on costly preventative interventions

Strategically increasing testing capacity, either by making diagnostic tests faster or more available, can reduce reliance on costly preventative interventions, such as distancing and shutdowns, according to a team of researchers led by Penn State.

28 Oct 2021

Breakthrough COVID infections in Northeast Italy showing waning vaccine protection

Researchers analyze an outbreak of breakthrough infections in a small nursing home in Northerneastern Italy.

28 Oct 2021

Study unravels how cells protect against influenza A viruses

Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature Microbiology.

28 Oct 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

Importance of boosters after priming with J&J Ad26.COV2.S COVID-19 vaccine

A new study compares healthcare workers who underwent homologous Ad26.COV2.S booster vaccination to those who underwent heterologous boosting.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

28 Oct 2021

Study offers hope for a new therapeutic option for patients with severe asthma

A new monoclonal antibody therapy shows promise in offering an alternative treatment for patients suffering from moderate-to-severe asthma. Research led by Michael E. Wechsler, MD, MMSc, director of the National Jewish Health Cohen Family Asthma Institute, found that itepekimab was safe and effective in a phase 2 trial published online today in the New England Journal of Medicine.

28 Oct 2021

Study suggests third dose of the Pfizer vaccine could reduce SARS-CoV-2 transmission

A new study examined protection against symptomatic coronavirus disease 2019 (COVID-19) from non-Delta variants using data from randomized control trials.

28 Oct 2021

Using fluvoxamine to treat COVID-19 patients reduces the need for prolonged hospitalization, trial shows

The results of a new randomized clinical trial, published in The Lancet Global Health, have demonstrated that using fluvoxamine to treat high-risk outpatients with early-diagnosed COVID-19 reduced the need for prolonged observation in an emergency setting or hospitalization, compared to a control group who received a placebo.

28 Oct 2021

Japanese study on SARS-CoV-2 breakthrough infections

Researchers evaluated SARS-CoV-2 incidence in Japan regarding the timing of the vaccination program and surge in COVID-19 cases among the staff of a large referral hospital in Tokyo. This study is posted to the medRxiv* preprint server.

28 Oct 2021

COVID vaccines deployed in US highly effective at reducing hospitalizations and deaths

Researchers in the United States have conducted a large-scale study showing that the two-dose regimen vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) appear to be highly effective and durable in reducing the risk of hospitalizations and deaths following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers emphasize that an effective vaccine should induce mucosal immunity and prevent the nasal entry of SARS-CoV-2.

27 Oct 2021

Researchers use a mathematical model to better understand the immune response to vaccines

When it comes to the design of a novel vaccine against viral infection, vaccine developers have to make several major decisions. One of them is the choice of what type of immune response they wish to induce.

27 Oct 2021

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

The heterologous ChAd/BNT combination confers better protection against SARS-CoV-2 infection than the homologous BNT/BNT combination in a real-world observational study of healthcare workers.

27 Oct 2021

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Researchers in the United States have conducted a study showing that Moderna’s coronavirus disease 2019 (COVID-19) vaccine provided durable protection against the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques.

26 Oct 2021

Efficacy News and Research

Study finds early fluvoxamine treatment among COVID-19 patients reduces hospitalization

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

More strategic COVID-19 testing can reduce reliance on costly preventative interventions

Breakthrough COVID infections in Northeast Italy showing waning vaccine protection

Study unravels how cells protect against influenza A viruses

How long does natural or vaccine-induced immunity to COVID last?

Importance of boosters after priming with J&J Ad26.COV2.S COVID-19 vaccine

A novel approach to improve the stability of Remdesivir

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Study offers hope for a new therapeutic option for patients with severe asthma

Study suggests third dose of the Pfizer vaccine could reduce SARS-CoV-2 transmission

Using fluvoxamine to treat COVID-19 patients reduces the need for prolonged hospitalization, trial shows

Japanese study on SARS-CoV-2 breakthrough infections

COVID vaccines deployed in US highly effective at reducing hospitalizations and deaths

New mechanisms for treating impregnable KRAS mutant cancers with statins

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers use a mathematical model to better understand the immune response to vaccines

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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