Infectious Diseases News and Research

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Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection.

20 Dec 2016

AMP publishes joint guidelines for interpretation, reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global, non-profit molecular diagnostics professional society, today published guideline recommendations for both clinical laboratory professionals and oncologists that assess the status of next-generation sequencing (NGS)-based cancer tests and establish standardized classification, annotation, interpretation, and reporting conventions for somatic sequence variants.

17 Dec 2016

Scientists discover mechanism that hijacks immune system's response to tuberculosis

Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target for the disease that kills more than 1 million people each year.

17 Dec 2016

Zika-linked abnormalities in fetuses more extensive and severe than previously thought

New UCLA-led research finds that Zika-linked abnormalities that occur in human fetuses are more extensive — and severe — than previously thought, with 46 percent of 125 pregnancies among Zika-infected women resulting in birth defects in newborns or ending in fetal death.

16 Dec 2016

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, as well as reduces body fat in an animal model.

16 Dec 2016

DuPont research project aims to enable global access for protein-based biologic medications

DuPont Industrial Biosciences today announced receipt of a grant from the Bill & Melinda Gates Foundation to support a new area of research. The research project, which commences immediately, aims to create new production systems to enable affordable, protein-based biologic medications, such as antibodies.

16 Dec 2016

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Dr. Irmela Jeremias from Helmholtz Zentrum München and her colleagues have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease.

15 Dec 2016

Childhood diarrhea from pathogens more common than previously thought?

The number of cases of childhood diarrhea, and its mortality toll of 500,000 per year, has not changed. Now, however, we can explain ~90% of the cases to specific pathogens. We can assign responsibility.

15 Dec 2016

Scientists develop first functional biological pacemaker from human stem cells

Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy.

15 Dec 2016

ECDC highlights need for increased efforts to prevent carbapenem-resistant A. baumannii outbreaks

Acinetobacter baumannii is the cause of difficult-to-treat infections in healthcare settings in Europe due to its increasing resistance to antimicrobial agents, in particular the carbapenems.

15 Dec 2016

NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

National Institutes of Healthscientists have established in mice a way to study potentially life-threatening meningitis caused by Salmonella.

9 Dec 2016

Researchers identify protein that degrades and inhibits infectious biofilms

Many infectious pathogens are difficult to treat because they develop into biofilms, layers of metabolically active but slowly growing bacteria embedded in a protective layer of slime, which are inherently more resistant to antibiotics.

9 Dec 2016

Rensselaer receives additional support to address childhood stunting in developing nations

Rensselaer Polytechnic Institute has received a grant of $993,384 from the Bill & Melinda Gates Foundation for continuing work on a novel data visualization platform that will harness and accelerate the analysis of vast amounts of data for the foundation's Healthy Birth, Growth, and Development Knowledge Integration initiative.

8 Dec 2016

Vaxine’s unique adjuvants boost effectiveness of vaccines for battling against infectious diseases

SUGAR-based adjuvants from Australia are boosting the effectiveness of vaccines to target some of the world’s deadliest diseases.

7 Dec 2016

New UTMB study sheds light on how Ebola effectively disables immune system

A new study at The University of Texas Medical Branch in Galveston sheds light on how Ebola so effectively disables the human immune system.

6 Dec 2016

Researchers develop new compound that can take down defenses in M. tuberculosis

Part of the reason tuberculosis-causing bacteria are so good at colonizing the human body is that they have defenses against the body's immune system.

6 Dec 2016

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and occasional pandemics.

5 Dec 2016

New UGA research finds pathogen's motility activates immune response

Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response.

1 Dec 2016

Researchers develop efficient computational method to create new drugs

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs.

1 Dec 2016

MDR-TB infection rates higher among migrants than general population, study finds

Multidrug-resistant tuberculosis (MDR-TB) is widespread globally with almost half a million cases documented in 2014.

1 Dec 2016

Infectious Diseases News and Research

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

AMP publishes joint guidelines for interpretation, reporting of sequence variants in cancer

Scientists discover mechanism that hijacks immune system's response to tuberculosis

Zika-linked abnormalities in fetuses more extensive and severe than previously thought

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

DuPont research project aims to enable global access for protein-based biologic medications

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Childhood diarrhea from pathogens more common than previously thought?

Scientists develop first functional biological pacemaker from human stem cells

ECDC highlights need for increased efforts to prevent carbapenem-resistant A. baumannii outbreaks

NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

Researchers identify protein that degrades and inhibits infectious biofilms

Rensselaer receives additional support to address childhood stunting in developing nations

Vaxine’s unique adjuvants boost effectiveness of vaccines for battling against infectious diseases

New UTMB study sheds light on how Ebola effectively disables immune system

Researchers develop new compound that can take down defenses in M. tuberculosis

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

New UGA research finds pathogen's motility activates immune response

Researchers develop efficient computational method to create new drugs

MDR-TB infection rates higher among migrants than general population, study finds

eBook: Advancing infectious disease vaccine development eBook

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