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New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Study explains why men are more at risk for neurodevelopmental disorders

A new study has shed light on the reason why males are more at risk than females for neurodevelopmental disorders such as autism, schizophrenia and ADHD.

4 Jul 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Research scientists from The Feinstein Institute for Medical Research and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, NY, in conjunction with their colleagues at Rockefeller University in New York City, have developed a new understanding of how certain psychiatric diseases - those that involve uncontrollable reactions to stimuli such as the high and low experiences attributed to bi-polar disorder, the impulsivity of an individual suffering from attention deficit hyperactivity disorder, and even suicidality - manifest and potentially can be treated. These findings were published today in Proceedings of the National Academy of Sciences.

3 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Novel sensing technology enables live and super-sensitive monitoring of biomarkers

The human body is an extremely complex molecular machine, the details of which can be followed through certain substances; so-called biomarkers.

2 Jul 2018

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today announced that U.S. researchers published scientific findings recommending development of anti-Liver Cancer Drugs based on a mechanism of action utilized by Namodenoson.

2 Jul 2018

Researchers find new marker for better prognosis in gastric and esophageal cancer

Tumors that develop at the transition of the stomach to the esophagus, so-called adenocarcinomas of the gastroesophageal transition, are still difficult to treat and the chances of recovery are still low.

2 Jul 2018

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

Bolstering the notion that RNA should be considered an important drug-discovery target, scientists at Scripps Research have found that several existing, FDA-approved anti-cancer drugs may work, in part, by binding tightly to RNA, the regulators of the basic activities of life within cells.

30 Jun 2018

Researchers discover novel function of fibroblast growth factor 2 for spermatogonial stem cell

A research team found a novel function of fibroblast growth factor 2, a self-renewal factor for spermatogonial stem cell which is the origin of the sperm production.

30 Jun 2018

Researchers discover inhibitory peptides to target central components in autophagy pathway

Autophagy, meaning "self-eating" in Greek, is a general metabolic mechanism adopted by nearly all the eukaryotic species, from the single cell yeast to humans.

30 Jun 2018

New therapeutic may help drug addicts avoid future drug use

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use.

30 Jun 2018

Glucose-based dietary supplement increases muscle-force in Duchenne muscular dystrophy mouse

A dietary supplement derived from glucose increases muscle-force production in the Duchenne muscular dystrophy mouse model by 50% in ten days, according to a study conducted by researchers from Université Laval's Faculty of Medicine and Centre hospitalier universitaire de Québec Research Centre-Université Laval.

30 Jun 2018

Molecule News and Research

New small molecules offer promising new way to treat autoinflammatory diseases

Study explains why men are more at risk for neurodevelopmental disorders

Seeing the Unexpected: Regulatory T Cells and Basophils

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Novel sensing technology enables live and super-sensitive monitoring of biomarkers

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Researchers find new marker for better prognosis in gastric and esophageal cancer

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

Researchers discover novel function of fibroblast growth factor 2 for spermatogonial stem cell

Researchers discover inhibitory peptides to target central components in autophagy pathway

New therapeutic may help drug addicts avoid future drug use

Glucose-based dietary supplement increases muscle-force in Duchenne muscular dystrophy mouse

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

Enzyme TLK2 could serve as potential therapies for breast cancer, brain condition

Scientists discover how the flu virus resets its trap

Bruker introduces innovative Sierra SPR-32 system at European SLAS 2018 meeting

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Hearing partially restored in deaf lab mice using novel therapy

A small molecule can inhibit chemotherapy resistance of certain tumors

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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