Clinical Trial News and Research

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B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Immune system contribution to tumor heterogeneity may influence liver cancer growth

Researchers at Mount Sinai School of Medicine say the immune system might contribute to the tumor heterogeneity seen in liver cancer that can affect the rate of cancer growth.

15 Jan 2020

Cannabinoids can alleviate some symptoms of endometriosis

Initial results from treating endometriosis in mice with cannabinoids suggest they can alleviate some symptoms of the disease, according to a new study in the open-access journal eLife.

14 Jan 2020

Eating more vegetables provides no extra protection for men with prostate cancer

National guidelines recommend that men with prostate cancer eat a vegetable-rich diet, suggesting it might decrease cancer progression and death.

14 Jan 2020

Probiotic drink could offer novel way to fight antibiotic-resistant bacteria

A probiotic drink could become a promising new weapon in the battle against antibiotic-resistant bacteria, after a team of Birmingham scientists engineered and patented a key genetic element that can tackle the genetic basis of resistance.

14 Jan 2020

Increased Vegetable Intake Fails to Slow Prostate Cancer Progression, Study Finds

Researchers in the United States have conducted a study investigating whether a telephone-based interventional program encouraging an increased intake of vegetables would slow disease progression among patients with early-stage prostate cancer.

14 Jan 2020

UPMC implants first patient in the U.S. with new wireless retinal device

UPMC has implanted the first patient in the United States with a new wireless retinal device as part of a clinical trial aimed at restoring partial sight to patients with advanced age-related macular degeneration, a disease that leads to permanent blindness.

13 Jan 2020

New program reduces abusive behaviors among middle school male athletes toward female peers

Coaching Boys Into Men, a program that seeks to prevent dating violence and sexual assault, reduces abusive behaviors among middle school male athletes toward their female peers, according to clinical trial results published today in JAMA Pediatrics.

13 Jan 2020

Blocking AHR receptor can reverse obesity, study finds

Obesity, a global epidemic, is a known contributor to several cancers, including breast, colon, and pancreatic. Stopping the obesity epidemic could be a critical aid in preventing and treating numerous cancers. Researchers with the laboratory of Craig Tomlinson, PhD, at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center have found a critical target in this cause.

13 Jan 2020

Study uncovers new subtypes of advanced pancreatic cancer

Researchers at the Ontario Institute for Cancer Research and the University Health Network have discovered detailed new information about the subtypes of pancreatic cancer. A better understanding of the disease groups may lead to new treatment options and improved clinical outcomes for this lethal disease.

13 Jan 2020

Sugar content in soft drinks has reduced by 29% in the UK, shows study

Lead researcher Lauren Bandy and her colleagues looked at the nutritional information of a range of soft drinks in the UK, including carbonated drinks, concentrates, 100% juice, juice drinks, energy drinks, sports drinks and bottled water, and combined this with sales data from 2015-2018.

12 Jan 2020

Insilico Medicine to showcase results of generative biology target ID system

Insilico Medicine, a biotechnology company developing end-to-end drug discovery pipelines utilizing the next-generation artificial intelligence, to present new results of its generative biology pipeline resulting in novel targets in liver disease.

12 Jan 2020

MGH surgeons perform first-of-its-kind heart transplant in New England

A team of surgeons and specialists at Massachusetts General Hospital is announcing an achievement in transplant surgery today, having recently performed the largest number of adult heart transplants in the country using what are known as Donation after Circulatory Death donor hearts.

11 Jan 2020

Mohamad Khazaei receives SCTM’s Young Investigator Award

Mohamad Khazaei, Ph.D., scientific associate in Dr. Michael Fehlings' lab at Krembil Research Institute, Toronto, is the latest recipient of STEM CELLS Translational Medicine's (SCTM) Young Investigator Award.

9 Jan 2020

New closed-loop system provides a way to help individuals with post-bariatric hypoglycemia

Gastric bypass vastly improves the health of the patients who elect to receive the surgery. Post-bariatric hypoglycemia, however, can be a severe complication experienced by 10 to 30 percent of patients.

9 Jan 2020

Harnessing biology and technology to develop much-needed treatments for depression

New research into the biology of depression, along with new and evolving technologies, provides the basis for developing the next generation of treatments for major depressive disorder, according to the special January/February issue of Harvard Review of Psychiatry.

9 Jan 2020

Nano-sized copper compounds together with immunotherapy can kill cancer cells

An interdisciplinary team of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina has succeeded in killing tumour cells in mice using nano-sized copper compounds together with immunotherapy. After the therapy, the cancer did not return.

9 Jan 2020

Smoking dormant HIV virus out into the open to develop a cure

Ever since antiretroviral treatments against HIV infection were introduced in 1996, scientists have eagerly been hunting for a cure for the disease.

9 Jan 2020

“Hotspotting” programs have virtually no impact on patient outcomes, indicates study

The new health care practice of "hotspotting" -- in which providers identify very high-cost patients and attempt to reduce their medical spending while improving care -- has virtually no impact on patient outcomes, according to a new study led by MIT economists.

9 Jan 2020

Diabetes drug could be repurposed as new treatment to prevent miscarriage

A drug designed to tackle diabetes could also be repurposed as the first treatment to prevent miscarriage by targeting the lining of the womb itself, according to a clinical trial led by the University of Warwick.

9 Jan 2020

Clinical Trial News and Research

B cell count tells how certain cancers will respond to immunotherapy

Immune system contribution to tumor heterogeneity may influence liver cancer growth

Cannabinoids can alleviate some symptoms of endometriosis

Eating more vegetables provides no extra protection for men with prostate cancer

Probiotic drink could offer novel way to fight antibiotic-resistant bacteria

Increased Vegetable Intake Fails to Slow Prostate Cancer Progression, Study Finds

UPMC implants first patient in the U.S. with new wireless retinal device

New program reduces abusive behaviors among middle school male athletes toward female peers

Blocking AHR receptor can reverse obesity, study finds

Study uncovers new subtypes of advanced pancreatic cancer

Sugar content in soft drinks has reduced by 29% in the UK, shows study

Insilico Medicine to showcase results of generative biology target ID system

MGH surgeons perform first-of-its-kind heart transplant in New England

Mohamad Khazaei receives SCTM’s Young Investigator Award

New closed-loop system provides a way to help individuals with post-bariatric hypoglycemia

Harnessing biology and technology to develop much-needed treatments for depression

Nano-sized copper compounds together with immunotherapy can kill cancer cells

Smoking dormant HIV virus out into the open to develop a cure

“Hotspotting” programs have virtually no impact on patient outcomes, indicates study

Diabetes drug could be repurposed as new treatment to prevent miscarriage

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