G Protein News and Research

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TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure.

23 May 2014

Research findings could lead to new approach to Alzheimer’s prevention

In surprise findings, scientists at The Scripps Research Institute have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer’s disease aggregates when it is produced in the brain. The results suggest that drugs that can boost the protein’s production specifically in neurons could one day help ward off Alzheimer’s disease.

22 May 2014

Acceleron, Celgene to give oral presentations on beta-thalassemia, myelodysplastic syndromes at EHA meeting

Acceleron Pharma Inc., a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of novel protein therapeutics for cancer and rare diseases, today reported that Acceleron, Celgene and investigators in the sotatercept and ACE-536 phase 2 clinical trials will give three oral presentations of interim data from ongoing studies in beta-thalassemia and myelodysplastic syndromes as well as a poster presentation of nonclinical data in sickle cell disease at the 19th Annual Congress of the European Hematology Association (EHA) in Milan, Italy from June 12-15, 2014.

22 May 2014

Agios Pharmaceuticals to present AG-221 Phase 1 study results at EHA meeting

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism (IEMs), today announced that new clinical data from the Phase 1 study of AG-221, an orally available, selective, potent inhibitor of the mutated IDH2 protein, will be highlighted in an oral presentation at the 19th Congress of the European Hematology Association (EHA) taking place June 12 -15, 2014 in Milan, Italy.

22 May 2014

Eisai launches new class of epilepsy treatment Fycompa in France

Fycompa (perampanel), the first in an entirely new class of treatment for partial onset seizures (the most common form of epilepsy), has today received reimbursement approval from the Comité Economique des Produits de Santé.

22 May 2014

New 5-layer flask enhances cell culture production

Porvair Sciences has announced a new 5-layer cell culture flask developed to fulfil the need of the growing number of applications that require large numbers of cells.

From Chromatrap® - Porvair Sciences Ltd 22 May 2014

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

A targeted gene silencing strategy blocks production of the dysfunctional huntingtin (Htt) protein, the cause of Huntington's disease, a fatal, inherited neurodegenerative disorder.

22 May 2014

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

In surprise findings, scientists at The Scripps Research Institute (TSRI) have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer's disease aggregates when it is produced in the brain.

22 May 2014

New project aims at saving lives of mothers, newborns in developing countries

Grand Challenges Canada, funded by the Government of Canada, today announces investments of $12 million in projects worldwide, aimed squarely at improving the health and saving the lives of mothers, newborns and children in developing countries.

22 May 2014

Researchers discover key proteins involved in DNA repair gone awry

Accumulation of DNA damage can cause aggressive forms of cancer and accelerated aging, so the body's DNA repair mechanisms are normally key to good health. However, in some diseases the DNA repair machinery can become harmful.

22 May 2014

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

A team led by a University of Maryland School of Medicine (UM SOM) researcher, working as a grantee from the National Institutes of Health (NIH), has identified a number of existing drugs that could be "repurposed" to fight outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV).

22 May 2014

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Alzheimer's is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans.

22 May 2014

TSRI scientists receives $2M grant to study effects of early nutrition on lifespan and overall health

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $2 million grant from the National Institute on Aging of the National Institutes of Health to study the effects of early nutrition on lifespan and overall health.

22 May 2014

Healthy diet provides lots of health benefits for patients with COPD

Sure, everyone knows a healthy diet provides lots of health benefits for patients with respiratory diseases, but now a new study has shown a direct link between eating fish, fruit and dairy products and improved lung function among patients with chronic obstructive pulmonary disease (COPD).

22 May 2014

New laser method provides a better understanding on how genes are controlled, regulated

Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell.

21 May 2014

Combination of metformin and rapamycin shows potential in treating aging and related diseases

A proven approach to slow the aging process is dietary restriction, but new research in the Linus Pauling Institute at Oregon State University helps explain the action of a drug that appears to mimic that process - rapamycin.

21 May 2014

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

A lean "Supermodel" mouse type has revealed the potentially critical role played by a largely unknown gene that regulates metabolism, findings that could provide new insight into diseases ranging from diabetes to obesity, a new study by UT-Southwestern Medical Center researchers suggests.

21 May 2014

Researchers show how bacteria responsible for strep throat can be used to fight colon cancer

Researchers at Western University (London, Canada) have shown how the bacteria primarily responsible for causing strep throat can be used to fight colon cancer. By engineering a streptococcal bacterial toxin to attach itself to tumour cells, they are forcing the immune system to recognize and attack the cancer.

21 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

Vitamin E-rich oils may increase incidence of asthma, says study

A large new Northwestern Medicine- study upends our understanding of vitamin E and ties the increasing consumption of supposedly healthy vitamin E-rich oils -- canola, soybean and corn - to the rising incidence of lung inflammation and, possibly, asthma.

21 May 2014

G Protein News and Research

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Research findings could lead to new approach to Alzheimer’s prevention

Acceleron, Celgene to give oral presentations on beta-thalassemia, myelodysplastic syndromes at EHA meeting

Agios Pharmaceuticals to present AG-221 Phase 1 study results at EHA meeting

Eisai launches new class of epilepsy treatment Fycompa in France

New 5-layer flask enhances cell culture production

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

New project aims at saving lives of mothers, newborns in developing countries

Researchers discover key proteins involved in DNA repair gone awry

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

TSRI scientists receives $2M grant to study effects of early nutrition on lifespan and overall health

Healthy diet provides lots of health benefits for patients with COPD

New laser method provides a better understanding on how genes are controlled, regulated

Combination of metformin and rapamycin shows potential in treating aging and related diseases

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

Researchers show how bacteria responsible for strep throat can be used to fight colon cancer

New compound restores learning, memory and other symptoms of AD in mice

Vitamin E-rich oils may increase incidence of asthma, says study

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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