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Specialists in infectious disease and global health convene at Philadelphia meeting

Nearly 2,500 physicians and scientists from institutions around the world such as the World Health Organization, the Centers for Disease Control and the National Institutes of Health will meet at the 56th American Society of Tropical Medicine and Hygiene's Annual Meeting on Nov. 4-8, in Philadelphia to discuss the latest research on infectious diseases and bioterrorist and global health threats.

24 Oct 2007

Role of cholesteryl ester hydrolase in reducing heart disease identified

Virginia Commonwealth University researchers have identified the role of a key enzyme called CEH in reducing heart disease, paving the way for new target therapies to reduce plaques in the arteries and perhaps in the future, help predict a patient's susceptibility to heart disease.

24 Oct 2007

Grape seed supplement studied for cardiovascular health benefits

Could some of the natural chemicals found in plants be powerful enough to improve cardiovascular health?

24 Oct 2007

Recent colds influence adverse respiratory events after surgery in children

For children undergoing general anesthesia for surgery or other procedures, the risks of several adverse respiratory (breathing-related) events are greater if the child has recently had a cold or other upper respiratory infection (URI).

24 Oct 2007

Uvulopalatopharyngoplasty may help those with obstructive sleep apnea

A procedure known as uvulopalatopharyngoplasty (UPPP) may help some patients improve or even eliminate their obstructive sleep apnea (OSA), according to a new study.

24 Oct 2007

Positive results for novel anti-cancer drug ECO-4601

Researchers report positive results from a Phase I/II clinical trial of a novel anti-cancer drug which offers two modes of action.

24 Oct 2007

Cannabis reduces pain only within a narrow dose range

Although smoking "moderate" doses of cannabis helps reduce pain in healthy research volunteers, pain is actually increased at high doses.

24 Oct 2007

New type of biodegradable nanoparticle for drug delivery

The spherical structures can encapsulate various fat-soluble medicines, which makes it easier to target tumour tissue. These nanoballs are highly promising carriers for the controlled release of anticancer drugs. Rijcken recently gained her doctorate for this research from Utrecht University.

24 Oct 2007

HIV combination antiretroviral drug therapy key to saving the lives of African children

Letting nurses and other trained health care workers deliver that therapy and monitor patients, especially when doctors are in short supply, is just as important to saving lives, according to a new study by the University of Alabama at Birmingham (UAB).

24 Oct 2007

How Rhesus Macaques and Humans have conquered the world

When it comes to their social behavior, people sometimes act like monkeys, or more specifically, like rhesus macaques, a type of monkey that shares with humans strong tendencies for nepotism and political maneuvering, according to research by Dario Maestripieri, an expert on primate behavior and an Associate Professor in Comparative Human Development and Evolutionary Biology at the University of Chicago.

24 Oct 2007

Combination targets offer new hope in fight against cancer

While some targeted therapies - drugs developed to attack specific molecules in the critical chemical pathways occurring within cancer cells - work well by themselves, increasingly researchers are finding that they work better when teamed with other targeted and conventional therapies.

24 Oct 2007

Simple blood test may accurately detect thoracic aneurysm disease

Yale scientists have discovered a way to use a simple blood test that may accurately detect thoracic aneurysm disease (TAA), which gives little warning and is almost always fatal if untreated.

24 Oct 2007

75% of hospital patients suffer from malnutrition regardless of their pathology

A study of 817 patients conducted in the Department of Nutrition and Bromatology at the University of Granada (UGR), in collaboration with the Unit of Nutrition and Dietetics at the hospital Virgen de las Nieves (Granada, Spain) of 817 patients, showed that 75% of hospitalised patients suffer from malnutrition regardless of their pathology.

24 Oct 2007

Shock-proof blood pressure meter

Blood pressure meters are more sensitive than you might think. Dropping them damages their mechanics and often leads to false readings.

24 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Review of percutaneous valve therapy

Researchers at TCT 2007, the annual scientific symposium of the Cardiovascular Research Foundation (CRF), will present new studies evaluating a rapidly advancing field within interventional cardiology: percutaneous procedures to repair and replace defective heart valves.

24 Oct 2007

Firing clay in unvented kilns could be a significant source of dioxins

The results came out of follow-up interviews with subjects who participated in the University of Michigan Dioxin Exposure Study, which measured dioxin levels in residents in Midland and the Tittabawassee River flood plain between Midland and Saginaw.

24 Oct 2007

SPIRIT III trial shows fewer major adverse cardiac events

Late breaking results from the SPIRIT III trial, presented at TCT 2007, the annual scientific symposium of the Cardiovascular Research Foundation, show that after 12 months, there were significantly fewer major adverse cardiac events (MACE) such as heart attacks, deaths from cardiac causes or repeat procedures (angioplasty or surgery) to clear the original vessel blockage after using a Xience V everolimus-eluting coronary stent than a Taxus paclitaxel-eluting stent.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007