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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Can video game–style exercise slow Alzheimer’s risk?

Gamified exercise training improves hippocampal volume and cognitive performance in mild neurocognitive disorders, offering potential for dementia prevention.

10 Sep 2025

Johns Hopkins team develops urine-based test for prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

9 Sep 2025

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

9 Sep 2025

Study highlights potential value of low-dose CT screening for lung cancer among Asian women

Results from the Female Asian Nonsmoker Screening Study (FANSS) highlight the potential value of low-dose CT (LDCT) screening for lung cancer among a growing but underserved population: Asian women with no history of smoking.

9 Sep 2025

Study identifies a reductive uric acid degradation pathway in anaerobic bacteria

Uric acid builds up in the blood when the body cannot excrete it efficiently, leading to painful gout attacks, kidney stones, and other complications.

8 Sep 2025

EEG ‘Fastball’ shows promise for spotting early memory loss in Alzheimer’s

This study introduces Fastball, an EEG method that accurately measures recognition memory in MCI, enhancing early dementia diagnosis and cognitive assessment.

8 Sep 2025

NYU Langone strengthens world-leading GI cancer program with renowned leaders

NYU Langone Health's Perlmutter Cancer Center announces the arrival of acclaimed cancer leaders Anirban Maitra, MD, and Manuel Hidalgo, MD, as co-directors of a new Gastrointestinal (GI) Cancer Center.

5 Sep 2025

Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials

Some of the populations with the highest risk for Alzheimer's disease remain greatly underrepresented in clinical trials-and a new study helps explain why.

5 Sep 2025

How fiber intake shapes your gut microbes’ digestion strategy

A study reveals how gut bacteria shift from fiber to mucus digestion, linking this change to inflammation in healthy adults and introducing the Muc2Plant ratio.

5 Sep 2025

Single hair strand reveals elemental patterns linked to ALS

Researchers at the Icahn School of Medicine at Mount Sinai have shown for the first time that a single strand of hair can reveal unique elemental patterns that distinguish people with amyotrophic lateral sclerosis (ALS) from healthy individuals.

4 Sep 2025

Penn State team develops wearable sensor to track health through minimal sweat

Available on-demand, in abundance and containing multiple biomarkers, sweat is an increasingly appealing medium for monitoring health, according to researchers at Penn State.

3 Sep 2025

Urine test identifies three biomarkers for accurate prostate cancer detection

2 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Tailored risk-based treatment does not improve outcomes in atrial fibrillation

An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

New ESC guidelines introduce unified approach to improve myocarditis and pericarditis care

New ESC Guidelines to improve the diagnosis and care of patients with myocarditis and pericarditis, have been published today at ESC Congress 2025.

30 Aug 2025

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Inflammation marker can help identify heart risk in women without traditional factors

Cardiologists have long known that up to half of all heart attacks and strokes occur among apparently healthy individuals who do not smoke and do not have high blood pressure, high cholesterol, or diabetes, the "standard modifiable risk factors" which doctors often call "SMuRFs."

29 Aug 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

Study brings hope for a more personalized approach to treat ER+ breast cancer

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

28 Aug 2025