Kidney News and Research

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Modifiable risk factors could double global kidney cancer cases by 2050

Modifiable risk factors such as obesity, smoking, lack of exercise, diabetes and hypertension are projected to be one of the main drivers of a steep rise in kidney cancer cases, doubling the amount worldwide over the next 25 years, according to a new study recently published in European Urology.

26 Sep 2025

Big loopholes in hospital charity care programs mean patients still get stuck with the tab

Quinn Cochran-Zipp went to the emergency room three times with severe abdominal pain before doctors figured out she had early-stage cancer in the germ cells of her right ovary.

25 Sep 2025

Stem cell treatment could help millions of people with end-stage kidney disease

More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood.

24 Sep 2025

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

24 Sep 2025

Researchers explore blueberries as a tool to support microbiota in early life

Researchers tested blueberry powder as one of the first complementary foods in human milk-fed infants. The trial found exploratory evidence that blueberries may support healthier gut microbiota development during early life.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

High levels of albumin in the urine linked to increased risk of dementia

A study shows that people with higher levels of the protein albumin in their urine are at increased risk of developing dementia. The study, led by researchers at Karolinska Institutet, is published in the scientific journal Journal of Internal Medicine.

24 Sep 2025

Uncontrolled hypertension claims more than 10 million lives every year

The World Health Organization (WHO) today released its second Global hypertension report, showing that 1.4 billion people lived with hypertension in 2024, yet just over one in five have it under control either through medication or addressing modifiable health risks.

24 Sep 2025

Misaligned perceptions lead to pediatric antibiotic overprescribing

Researchers from USC and Duke report that the persistent "know-do gap" - where clinicians know guidelines but practice differently - is the primary driver of antibiotic overprescribing for pediatric diarrhea in India's private sector, not lack of knowledge, point-of-sale profits, or stockouts of clinically recommended treatments such as oral rehydration salts (ORS).

23 Sep 2025

Fat distribution appears to influence cancer risk

How fat is distributed in people's bodies could make a difference to their risk of certain cancers, according to new research led by the University of Bristol. The international study is published in the Journal of the National Cancer Institute (JNCI) today [24 September].

23 Sep 2025

"Light-touch" diabetes intervention can be successfully integrated into clinical workflows

This study tested whether a referral order inside the Epic electronic health record (EHR) could help primary care clinicians refer patients to community-based diabetes prevention programs (DPPs), an important public health strategy to reduce incident type 2 diabetes, and whether patients enrolled after referral.

23 Sep 2025

Regular phone support after losing weight helps people to keep the pounds off

People who receive regular phone support after losing weight are more likely to keep the pounds off - but getting extra calls when at risk for regaining weight doesn't provide additional benefit, according to a new study led by Kathryn M. Ross, Ph.D., M.P.H., senior research scientist at Advocate Aurora Research Institute and associate professor in the Department of Social Sciences and Health Policy at Wake Forest University School of Medicine.

23 Sep 2025

A single drug stabilizes nearly all mutations of key kidney protein

A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilize nearly all mutated versions of a human protein, regardless of where the mutation is in the sequence.

23 Sep 2025

Orforglipron pill improves heart and metabolic risk factors in trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase 3 clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions.

22 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

New dialysis filter shows promise for improving survival and health in kidney failure patients

Researchers at London Health Sciences Centre Research Institute (LHSCRI) and Western University's Schulich School of Medicine & Dentistry have launched a clinical trial that is evaluating a new type of dialysis filter called Elisio HX that may significantly improve outcomes for people living with kidney failure across Canada.

22 Sep 2025

PRMT5 inhibition induces ferroptosis and enhances immunotherapy efficacy in renal cell carcinoma

Ferroptosis, a regulated cell death mechanism, is emerging as a promising target for cancer therapy. The process is mediated by the activity of acyl-CoA synthetase family member 4 (ACSL4) protein.

22 Sep 2025

New cryopreservation technique reduces cracking risk in organ freezing

Cryopreservation, or preserving biological tissue by cooling it to subzero temperatures, may bring to mind works of science fiction.

19 Sep 2025

Oral GLP-1 drug orforglipron achieves significant weight loss in global trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase III clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions

18 Sep 2025