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Newly discovered brain pattern could improve the diagnosis of mental health disorders

A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth).

18 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

Researchers to investigate why exercise makes some people healthier than others

Why do some people benefit so much from exercise while others enjoy few health gains or even suffer harm? Does age matter when it comes to exercise's health benefits? Are there "molecular signatures" - sets of genes, proteins and other variables ¬- that reveal the answers?

11 Dec 2020

Skin may help to predict future heart problems

Our skin tells us when we've spent too much time in the sun or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin can also foretell issues unrelated to the protective barrier.

10 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Improved understanding of exposome-drug interactions could help prescribe effective drug doses

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

2 Dec 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

UTHSC and Regeneron partner to advance precision medicine

The University of Tennessee Health Science Center has entered into an agreement with the Regeneron Genetics Center, a subsidiary of Regeneron Pharmaceuticals, Inc., for the company to sequence DNA that has been voluntarily collected and stored as part of a biorepository initiative UTHSC is building in collaboration with its partner teaching hospitals.

18 Nov 2020

Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to severe COVID-19, according to translational research by an international team coordinated by researchers from Karolinska Institutet in Sweden.

16 Nov 2020

New Cambridge Centre aims to transform precision medicine and biomedical discoveries

A new center at the University of Cambridge, in collaboration with AstraZeneca and GSK, aims to use AI to make medical discoveries, accelerate the development of precision medicine and develop new treatments

12 Nov 2020

Researchers identify new prognostic markers for colon cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs).

11 Nov 2020

REGENHU launches its next generation 3D Bioprinter and software, the R-GEN series and SHAPER, in its mission to revolutionize medicine

REGENHU, a leading global bioprinting company, today announced the launch of the R-GEN platform and SHAPER, a new bioprinter and software designed to cover the entire biofabrication process.

From regenHU Ltd. 4 Nov 2020

Global collaboration provides a COVID-19 disease map

A collaboration of researchers from 120 different institutes across 30 countries including France, Germany, Australia, Japan, USA, India, Turkey, Brazil, and Canada initiated an effort to develop a COVID-19 Disease Map - a collection of computational models and diagrams of molecular mechanisms implicated in COVID-19.

2 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin Division 30 Oct 2020

SMART researchers develop novel microcarrier for large-scale cell production

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have developed a novel microcarrier for large-scale cell production and expansion that offers higher yield and cost-effectiveness compared to traditional methods, and reduces steps required in the cell retrieval process.

29 Oct 2020

Researchers use viral signatures to reveal transmission patterns of SARS-CoV-2

The coronavirus, responsible for the COVID-19 pandemic, has one official name--SARS-CoV-2. But according to virologists, mutations lead to hundreds of genetically-distinct versions of the virus.

23 Oct 2020

Biodynamic imaging illuminates ovarian cancer treatments

Scientists estimate that nearly 60% of all cancer patients do not respond effectively to chemotherapy treatments. Even worse - many of those same patients experience toxic and sometimes deadly side effects.

22 Oct 2020