Oxygen News and Research

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New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

Removing of carotid body appears to be effective for high blood pressure

Removing one of the tiniest organs in the body has shown to provide effective treatment for high blood pressure. The discovery, made by University of Bristol researchers and published in Nature Communications, could revolutionise treatment of the world's biggest silent killer.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Omecamtiv mecarbil, a cardiac myosin-activator, did not achieve its primary efficacy endpoint in reducing dyspnoea (shortness of breath) in patients with acute heart failure, according to the results of the phase II ATOMIC-AHF (Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure) study.

3 Sep 2013

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Dr Laukkanen said: "Sudden cardiac death (SCD) accounts for approximately 50% of deaths from coronary heart disease. SCD typically occurs shortly after the onset of symptoms, leaving little time for effective medical interventions, and most cases occur outside hospital with few or no early warning signs. Finding ways to identify individuals at elevated risk of SCD would allow early interventions on risk factors to be implemented."

2 Sep 2013

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

A drug proven effective for treatment of adults and children with sickle cell anemia reduced hospitalizations and cut annual estimated medical costs by 21 percent for affected infants and toddlers, according to an analysis led by St. Jude Children's Research Hospital. The report appears today in the advance online edition of the journal Pediatrics.

2 Sep 2013

Women may need to exercise one day a week to improve strength

A study by researchers at the University of Alabama at Birmingham (UAB) reveals that women over age 60 may need to exercise only one day a week to significantly improve strength and endurance.

31 Aug 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

Findings lead to new drugs that block cancers from spreading to bone

When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system.

30 Aug 2013

UT finds way to blend passion for chemistry with ideals of environmental sustainability

A University of Texas at Arlington junior who found a way to blend a passion for chemistry with ideals of environmental sustainability is getting help from the U.S. Environmental Protection Agency to further his education and his research.

29 Aug 2013

Scientists develop complex human brain tissue in 3D culture system

Complex human brain tissue has been successfully developed in a three-dimensional culture system established in an Austrian laboratory. The method described in the current issue of NATURE allows pluripotent stem cells to develop into cerebral organoids - or "mini brains" - that consist of several discrete brain regions.

29 Aug 2013

WPI researchers receive NIH grant to develop cell therapies for healing cardiac muscle

The National Institutes of Health (NIH) has awarded a five-year, $1.94 million grant to a biomedical research team at Worcester Polytechnic Institute (WPI) working at the forefront of cell therapies for healing cardiac muscle damaged by heart attack or chronic disease.

29 Aug 2013

Testosterone improves exercise capacity in men with COPD

A systematic review and meta-analysis confirms that testosterone therapy improves exercise capacity in men with chronic obstructive pulmonary disease.

28 Aug 2013

High intensity interval training offers maximum benefits to women

Interval training is a well-known way to get the maximum benefits of exercise in the shortest amount of time. New research shows that when it comes to running, women may get more out of high intensity interval training (HIIT) than their male counterparts.

28 Aug 2013

'Helper cells' improve survival rate of transplanted stem cells, finds study

Like volunteers handing out cups of energy drinks to marathon runners, specially engineered "helper cells" transplanted along with stem cells can dole out growth factors to increase the stem cells' endurance, at least briefly, Johns Hopkins researchers report.

28 Aug 2013

Oxygen-generating compound could preserve muscle tissue after severe injury

The same compound in a common household clothes detergent shows promise as a treatment to preserve muscle tissue after severe injury. Researchers at the Wake Forest Baptist Medical Center's Institute for Regenerative Medicine hope the oxygen-generating compound could one day aid in saving and repairing limbs and tissue.

27 Aug 2013

Levels of mercury in Pacific Ocean fish likely to increase in coming decades

University of Michigan researchers and their University of Hawaii colleagues say they've solved the longstanding mystery of how mercury gets into open-ocean fish, and their findings suggest that levels of the toxin in Pacific Ocean fish will likely rise in coming decades.

26 Aug 2013

Scanning technique reveals how brain tumor responds to drug administered

A new scanning technique developed by Danish and US researchers reveals how susceptible patients with aggressive brain cancer are to the drugs they receive. The research behind the ground-breaking technique has just been published in Nature Medicine.

26 Aug 2013

Innovation that speeds up pure oxygen production wins 2013 Curtin Commercial Innovation Awards

An innovation that speeds up pure oxygen production, a medical device that treats neck pain and technology that regenerates tissue in ulcers are the winners of the 2013 Curtin Commercial Innovation Awards.

23 Aug 2013

Oxygen News and Research

New mechanism operates specific protein in brain to bring delay in aging

Removing of carotid body appears to be effective for high blood pressure

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Leisure-time physical activity might reduce risk of SCD among men with low CRF

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

Women may need to exercise one day a week to improve strength

New angle for developing drugs to prevent thrombosis and heart attack

Findings lead to new drugs that block cancers from spreading to bone

UT finds way to blend passion for chemistry with ideals of environmental sustainability

Scientists develop complex human brain tissue in 3D culture system

WPI researchers receive NIH grant to develop cell therapies for healing cardiac muscle

Testosterone improves exercise capacity in men with COPD

High intensity interval training offers maximum benefits to women

'Helper cells' improve survival rate of transplanted stem cells, finds study

Oxygen-generating compound could preserve muscle tissue after severe injury

Levels of mercury in Pacific Ocean fish likely to increase in coming decades

Scanning technique reveals how brain tumor responds to drug administered

Innovation that speeds up pure oxygen production wins 2013 Curtin Commercial Innovation Awards

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