Efficacy News and Research

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Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The efficacy and safety of a DNA-based vaccine are investigated, finding that the unique vaccine imparts a robust and long-lasting immunogenic response.

15 Oct 2021

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The results of a phase 2 clinical trial featuring a SARS-CoV-2 recombinant protein vaccine developed by GlaxoSmithKline are reported, demonstrating a favorable immune response amongst both naïve and non-naïve adults with an acceptable safety profile.

15 Oct 2021

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study.

15 Oct 2021

Nasal photodisinfection therapy for COVID-19 patients may reduce the severity of lower tract respiratory disease

Research on the efficacy of nasal photodisinfection therapy for treating asymptomatic and early stage COVID-19 patients has found that it may reduce the severity of lower tract respiratory disease.

15 Oct 2021

Experts review progress in using photobiomodulation therapy to treat diverse brain disorders

Photobiomodulation (PBM) offers exciting opportunities for improving the life of patients with a diverse range of brain disorders.

14 Oct 2021

Brief interventions delivered in doctors' offices can lead to reductions in drinking

A new systematic review and meta-analysis has found that alcohol-targeted brief interventions (short, structured, one-to-one conversations about drinking designed to motivate changes in risky behavior) delivered in doctors' offices and similar medical settings can produce small but useful reductions in drinking.

14 Oct 2021

Study reveals a highly effective COVID-19 screening system utilizing a live cell-based assay

A new study reports a cell-based assay that involved the isolation and quantification of SARS-CoV-2 Mpro in human cells in the absence of other proteins.

14 Oct 2021

Study finds relatively low rate of COVID-19 infection following full vaccination in North Carolina

A recent study seeks to investigate the characteristics of individuals with breakthrough infections post-vaccination in North Carolina, USA.

14 Oct 2021

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

13 Oct 2021

Scientists suggest a new approach to mitigating the collateral damage from antibiotics

Antibiotics help us to treat bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in our gut, weakening one of our body's first lines of defense against pathogens and compromising the multiple beneficial effects our microbiota has for our health.

13 Oct 2021

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Scientists have characterized T-cell, B-cell, and IgG responses to S antigenic sequences to evaluate vaccine effectiveness.

13 Oct 2021

Researchers identify how estrogens can influence the growth of melanoma

The link between estrogens and breast cancer has long been defined, but a Duke-led research team has identified how these hormones can also influence the growth of other cancers, notably melanoma.

12 Oct 2021

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

Researchers review diverse computational methods for drug/inhibitor design and enzymes as potential targets for inhibitors to treat coronaviruses diseases.

12 Oct 2021

Typhoid vaccine found to be 84% effective in preventing the disease in children

A vaccine has proved safe and effective in protecting children against typhoid, raising hopes of fighting the disease in Sub-Saharan Africa, a study says.

12 Oct 2021

Novel vaccine demonstrates high efficacy for prevention of COVID-19

The clinical trial studied the efficacy of Novavax’s COVID-19 vaccine, NVX-CoV2373, and found it highly effective in preventing mild, moderate, and severe COVID-19 after full vaccination.

12 Oct 2021

Research provides insights on colorectal cancers’ immunotherapy resistance

Immune checkpoint inhibitors, which unleash the immune response against tumor cells, have revolutionized cancer treatment; however, the medications aren't effective in a large number of patients, including those with colorectal cancer.

11 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Researchers addressed the question of using reporter particles pseudotyped with the S protein of SARS-CoV-2, which are suitable tools to examine SARS-CoV-2 neutralization antibodies.

11 Oct 2021

Sero-epidemiological insights into pathways to COVID-19 immunity

A new study posted to the medRxiv* server attempts to utilize serology as a tool to identify disparities in infection rates and vaccination coverage.

10 Oct 2021

Research finds different antibody responses following COVID vaccination and natural infection

A new study published in the journal Nature attempted to investigate memory B cell evolution 5 months after vaccination with mRNA vaccines such as Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) in SARS-CoV-2 naïve individuals. The study explored various aspects of memory B cell antibody response like neutralizing response, affinity, epitope targeting, and neutralizing breadth.

10 Oct 2021

Efficacy News and Research

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

Nasal photodisinfection therapy for COVID-19 patients may reduce the severity of lower tract respiratory disease

Experts review progress in using photobiomodulation therapy to treat diverse brain disorders

Brief interventions delivered in doctors' offices can lead to reductions in drinking

Study reveals a highly effective COVID-19 screening system utilizing a live cell-based assay

Study finds relatively low rate of COVID-19 infection following full vaccination in North Carolina

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

Scientists suggest a new approach to mitigating the collateral damage from antibiotics

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Researchers identify how estrogens can influence the growth of melanoma

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

Typhoid vaccine found to be 84% effective in preventing the disease in children

Novel vaccine demonstrates high efficacy for prevention of COVID-19

Research provides insights on colorectal cancers’ immunotherapy resistance

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Sero-epidemiological insights into pathways to COVID-19 immunity

Research finds different antibody responses following COVID vaccination and natural infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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